ABI3BP

Description		ABI family member 3 binding protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix
	Molecular Function	Extracellular Matrix Structural Constituent
	Biological Process	Positive Regulation Of Cell-substrate Adhesion Extracellular Matrix Organization
Pathways
Drugs
Diseases
GWAS		Acute urticaria and angioedema (non-steroidal anti-inflammatory drug-induced) ( 24236485) Alcohol dependence ( 26365420) Asthma (childhood onset) ( 23829686) Carotid plaque burden ( 28282560) Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444) Gut microbiota relative abundance (Faecalibacterium) ( 33208821) Joint mobility (Beighton score) ( 27182965) Multiple sclerosis ( 31604244) Optic disc area ( 25631615 28073927) Optic disc size ( 31809533) Post bronchodilator FEV1 in COPD ( 26634245) Refractive error ( 32231278) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
Interacting Genes		6 interacting genes: ABI3 CBX1 FZD5 GOT1 GRB2 MBNL1
Entrez ID		25890
HPRD ID		09380
Ensembl ID		ENSG00000154175
Uniprot IDs		D3YTG3 F6R962 H7C556 Q7Z7G0
PDB IDs
Enriched GO Terms of Interacting Partners?		Branching Involved In Labyrinthine Layer Morphogenesis L-cysteine Transaminase Activity L-glutamate Catabolic Process To Aspartate L-aspartate:2-oxoglutarate Aminotransferase Activity Aspartate Biosynthetic Process Phosphatidylserine Decarboxylase Activity L-glutamate Biosynthetic Process Embryonic Morphogenesis Guanyl-nucleotide Exchange Factor Adaptor Activity Anatomical Structure Morphogenesis Grb2-EGFR Complex Oxaloacetate Metabolic Process Transdifferentiation Carboxylic Acid Binding L-aspartate Catabolic Process Glutamate Biosynthetic Process L-glutamate Catabolic Process Malate-aspartate Shuttle Response To Transition Metal Nanoparticle Glycerol Biosynthetic Process Negative Regulation Of Mitochondrial Depolarization Aspartate Metabolic Process Morphogenesis Of A Branching Structure Morphogenesis Of A Branching Epithelium Regulation Of Lymphocyte Mediated Immunity Neurotrophin TRKA Receptor Binding Chorionic Trophoblast Cell Differentiation Regulation Of Chorionic Trophoblast Cell Proliferation Intestinal Epithelial Cell Maturation Glandular Epithelial Cell Maturation Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Spemann Organizer Formation Post-embryonic Camera-type Eye Development Male Pronucleus Actin-based Cell Projection Negative Regulation Of Lamellipodium Assembly Negative Regulation Of Ruffle Assembly Regulation Of Cell Junction Assembly Anterior/posterior Axis Specification, Embryo Columnar/cuboidal Epithelial Cell Maturation Synapse Organization Female Pronucleus Defense Response To Tumor Cell Negative Regulation Of Collagen Biosynthetic Process Negative Regulation Of Cytosolic Calcium Ion Concentration Glycerol Metabolic Process Cell Differentiation Morphogenesis Of An Epithelium Insulin Receptor Substrate Binding Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
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