TRMT2A and AIMP2

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TRMT2A	AIMP2
Gene Name		tRNA methyltransferase 2 homolog A (S. cerevisiae)	aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Cytosol Membrane
	Molecular Function	Nucleotide Binding RNA Methyltransferase Activity Poly(A) RNA Binding	Protein Binding
	Biological Process	RNA Methylation RNA Processing	TRNA Aminoacylation For Protein Translation Apoptotic Process Negative Regulation Of Cell Proliferation Gene Expression Positive Regulation Of Protein Ubiquitination Type II Pneumocyte Differentiation
Pathways			Cytosolic tRNA aminoacylation tRNA Aminoacylation
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AIMP2 ANXA7 APP ATP1B1 CDK4 CDKN1A GADD45G PIK3R3 PIN1 RASA1 RCC1 SMN1 TK1 TNFSF11	48 interactors: ACTB AIMP1 APP BCAS2 BLOC1S4 BYSL C19orf57 CEP170P1 CHD3 DARS DARS2 DEAF1 DSN1 EPRS EPS8 FGB FHL3 FUBP1 GYS1 ICE1 KARS KDR KIAA1377 KLC2 LMO2 LMO3 LNX1 LUC7L2 MATR3 MCF2L MIS18A NDEL1 NECAB2 NGFRAP1 PARK2 PCMT1 PLEKHF2 PPP2R1A PRKAA2 PSME1 TANK TERF2IP TFIP11 TP53 TRAF2 TRMT2A ZC3H12A ZGPAT
Entrez ID		27037	7965
HPRD ID		13719	02915
Ensembl ID		ENSG00000099899	ENSG00000106305
Uniprot IDs		Q8IZ69	A8MU58 Q13155
PDB IDs			4DPG
Enriched GO Terms of Interacting Partners?		Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Calcium Ion Homeostasis Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Response To Hyperoxia Positive Regulation Of Protein Modification Process Metal Ion Homeostasis Response To Toxic Substance Developmental Process Positive Regulation Of Hydrolase Activity Response To Stress Positive Regulation Of Transferase Activity Ion Homeostasis Response To Organic Substance Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Positive Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Multicellular Organismal Development Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Calcium Ion Homeostasis Positive Regulation Of Corticotropin-releasing Hormone Secretion Fetal Process Involved In Parturition Positive Regulation Of Protein Phosphorylation Positive Regulation Of Fibroblast Proliferation	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Component Assembly TRNA Aminoacylation For Protein Translation Axon Cargo Transport TRNA Aminoacylation Cell Cycle Process NcRNA Metabolic Process Mitotic Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Autophagy Mitotic Cell Cycle Apoptotic Process Platelet Aggregation Negative Regulation Of Reactive Oxygen Species Metabolic Process Programmed Cell Death Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Mitochondrion Degradation Protein Complex Assembly Microtubule-based Transport Immune System Process Cell Death Death TRNA Metabolic Process Cellular Response To Organic Substance Cytoskeleton-dependent Intracellular Transport Blood Coagulation Cell Cycle Cellular Macromolecule Biosynthetic Process Hemostasis Positive Regulation Of Peptidase Activity Macromolecule Biosynthetic Process Cellular Process Cellular Amino Acid Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Proteolysis Positive Regulation Of Metabolic Process Regulation Of Intracellular Signal Transduction Regulation Of Apoptotic Process Cellular Metabolic Process Response To Wounding Regulation Of Signaling Regulation Of Cellular Ketone Metabolic Process
Tagcloud ?			4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Difference) ?			4x20 abl abrogated bbb c57 compacts dopaminergic e3 easily endothelium inno irreversible microvessel mitigated mptp nanomolar neurodegeneration neuroprotective nigra nitrative parkin pars pd pharmacokinetic striatum substantia th translated ubiquitously
Tagcloud (Intersection) ?