TRMT2A and ATP1B1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TRMT2A	ATP1B1
Gene Name		tRNA methyltransferase 2 homolog A (S. cerevisiae)	ATPase, Na+/K+ transporting, beta 1 polypeptide
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Intercalated Disc Basolateral Plasma Membrane Apical Plasma Membrane Vesicle Sarcolemma Extracellular Vesicular Exosome
	Molecular Function	Nucleotide Binding RNA Methyltransferase Activity Poly(A) RNA Binding	ATPase Activator Activity Sodium:potassium-exchanging ATPase Activity Protein Binding MHC Class II Protein Complex Binding ATPase Binding
	Biological Process	RNA Methylation RNA Processing	Response To Hypoxia Cellular Calcium Ion Homeostasis Cellular Sodium Ion Homeostasis Cell Adhesion Blood Coagulation Potassium Ion Import Regulation Of Gene Expression Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Export From Cell Protein Transport Into Plasma Membrane Raft Protein Stabilization Leukocyte Migration Transmembrane Transport Relaxation Of Cardiac Muscle Cardiac Muscle Contraction Protein Localization To Plasma Membrane Membrane Repolarization Membrane Repolarization During Cardiac Muscle Cell Action Potential Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export From Cell Positive Regulation Of Calcium:sodium Antiporter Activity Positive Regulation Of Potassium Ion Import
Pathways			Ion transport by P-type ATPases Ion channel transport Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS			QT interval ( 23166209 19305409)
Protein-Protein Interactions		14 interactors: AIMP2 ANXA7 APP ATP1B1 CDK4 CDKN1A GADD45G PIK3R3 PIN1 RASA1 RCC1 SMN1 TK1 TNFSF11	17 interactors: BACE1 BARD1 BRCA1 CRIP2 DDAH2 EGFR EZH2 FXYD1 FXYD7 GCH1 KMT2B LRIF1 NDRG2 PAXIP1 PSME1 TRMT2A USP4
Entrez ID		27037	481
HPRD ID		13719	01663
Ensembl ID		ENSG00000099899	ENSG00000143153
Uniprot IDs		Q8IZ69	A3KLL5 A6NGH2 P05026
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Calcium Ion Homeostasis Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Response To Hyperoxia Positive Regulation Of Protein Modification Process Metal Ion Homeostasis Response To Toxic Substance Developmental Process Positive Regulation Of Hydrolase Activity Response To Stress Positive Regulation Of Transferase Activity Ion Homeostasis Response To Organic Substance Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Positive Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Multicellular Organismal Development Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Calcium Ion Homeostasis Positive Regulation Of Corticotropin-releasing Hormone Secretion Fetal Process Involved In Parturition Positive Regulation Of Protein Phosphorylation Positive Regulation Of Fibroblast Proliferation	Regulation Of Histone H3-K4 Methylation Regulation Of Histone Methylation Regulation Of Protein Ubiquitination Protein K6-linked Ubiquitination Negative Regulation Of Cell Cycle Cellular Nitrogen Compound Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Histone H3-K4 Methylation Histone Lysine Methylation Signal Transduction In Response To DNA Damage Peptidyl-lysine Methylation Nitrogen Compound Metabolic Process Nitric Oxide Biosynthetic Process Regulation Of Protein Metabolic Process Reactive Oxygen Species Metabolic Process Signal Transduction By P53 Class Mediator Positive Regulation Of Histone Acetylation Histone Methylation Regulation Of Histone Modification Positive Regulation Of Peptidyl-lysine Acetylation Positive Regulation Of Protein Acetylation Positive Regulation Of Protein Ubiquitination Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Regulation Of Cellular Amino Acid Metabolic Process Positive Regulation Of DNA Metabolic Process Regulation Of Reactive Oxygen Species Metabolic Process Methylation Nitric Oxide Metabolic Process Positive Regulation Of Metabolic Process Reactive Nitrogen Species Metabolic Process Regulation Of Cellular Protein Metabolic Process Protein Polyubiquitination Histone H3-K4 Methylation Protein Methylation Positive Regulation Of Histone Methylation Positive Regulation Of DNA Repair Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Protein Modification Process Negative Regulation Of Apoptotic Process Regulation Of Cellular Ketone Metabolic Process Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Programmed Cell Death Regulation Of Cell Cycle Regulation Of Chromosome Organization Regulation Of Gene Expression, Epigenetic Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Regulation Of Histone Acetylation Negative Regulation Of Cell Death
Tagcloud ?			activin belongs bip caps elusive folding grp78 homeobox hspa5 hspa5mo knock lhx1 lim malformation morphants morpholino mos multifunctional oligonucleotides participates pax2 pronephric pronephros rescued residing serves specification unfolded xenopus
Tagcloud (Difference) ?			activin belongs bip caps elusive folding grp78 homeobox hspa5 hspa5mo knock lhx1 lim malformation morphants morpholino mos multifunctional oligonucleotides participates pax2 pronephric pronephros rescued residing serves specification unfolded xenopus
Tagcloud (Intersection) ?