TRMT2A and RCC1

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		TRMT2A	RCC1
Gene Name		tRNA methyltransferase 2 homolog A (S. cerevisiae)	regulator of chromosome condensation 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nuclear Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Cytoplasm Nuclear Membrane
	Molecular Function	Nucleotide Binding RNA Methyltransferase Activity Poly(A) RNA Binding	Chromatin Binding Ran Guanyl-nucleotide Exchange Factor Activity Protein Binding Nucleosomal DNA Binding Histone Binding
	Biological Process	RNA Methylation RNA Processing	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Division Regulation Of Mitotic Nuclear Division Viral Process Positive Regulation Of Ran GTPase Activity Spindle Assembly Cell Division
Pathways			HIV Life Cycle Rev-mediated nuclear export of HIV RNA HIV Infection Nuclear import of Rev protein Rev-mediated nuclear export of HIV RNA Host Interactions of HIV factors Interactions of Rev with host cellular proteins Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		14 interactors: AIMP2 ANXA7 APP ATP1B1 CDK4 CDKN1A GADD45G PIK3R3 PIN1 RASA1 RCC1 SMN1 TK1 TNFSF11	50 interactors: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 FAF1 FLAD1 GNB2 HADHB HIST1H3A HIST1H4A HIST2H2AA3 HIST2H2AC HIST2H2BE HMGA1 HOXD8 KMT2B KPNA3 KPNA4 KPNB1 LRIF1 NGFR NTMT1 NUDT21 NUP98 PDHB PKM PTMA RAN RANBP1 RANBP3 RPA1 SDF4 SPRED1 TLE1 TP53 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		27037	1104
HPRD ID		13719	01559
Ensembl ID		ENSG00000099899	ENSG00000180198
Uniprot IDs		Q8IZ69	P18754 Q5T081
PDB IDs			1A12 1I2M
Enriched GO Terms of Interacting Partners?		Regulation Of Catalytic Activity Positive Regulation Of Catalytic Activity Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Protein Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Kinase Activity Regulation Of Phosphorylation Regulation Of Cell Cycle Process Regulation Of Cell Cycle Regulation Of Phosphorus Metabolic Process Regulation Of Protein Phosphorylation Calcium Ion Homeostasis Regulation Of Metabolic Process Regulation Of Protein Kinase Activity Regulation Of Cellular Protein Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Protein Metabolic Process G1/S Transition Of Mitotic Cell Cycle Response To Hyperoxia Positive Regulation Of Protein Modification Process Metal Ion Homeostasis Response To Toxic Substance Developmental Process Positive Regulation Of Hydrolase Activity Response To Stress Positive Regulation Of Transferase Activity Ion Homeostasis Response To Organic Substance Regulation Of Mitotic Cell Cycle Phase Transition Response To Abiotic Stimulus Positive Regulation Of Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Phase Transition Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Multicellular Organismal Development Phosphorylation Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Anatomical Structure Development Positive Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Process Positive Regulation Of Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Cellular Calcium Ion Homeostasis Positive Regulation Of Corticotropin-releasing Hormone Secretion Fetal Process Involved In Parturition Positive Regulation Of Protein Phosphorylation Positive Regulation Of Fibroblast Proliferation	Protein Localization To Nucleus Protein Import Into Nucleus Nuclear Import Intracellular Transport Of Virus Protein Localization To Organelle Protein Import Nucleocytoplasmic Transport Nuclear Transport Cell Cycle Mitotic Cell Cycle DNA Packaging Cellular Component Assembly Protein Complex Assembly Cell Cycle Process Chromatin Assembly Cellular Localization Cellular Protein Localization Chromatin Organization NLS-bearing Protein Import Into Nucleus Viral Process Protein Localization Ribosomal Small Subunit Export From Nucleus Chromatin Assembly Or Disassembly DNA Conformation Change Cellular Nitrogen Compound Metabolic Process Chromosome Organization Viral Life Cycle Mitotic Cell Cycle Process Cellular Metabolic Process Positive Regulation Of Cell Aging Establishment Of Protein Localization To Organelle Organelle Organization Establishment Of Protein Localization Ribosomal Large Subunit Export From Nucleus Nitrogen Compound Metabolic Process Intracellular Transport Ribosomal Subunit Export From Nucleus DNA Replication-dependent Nucleosome Assembly Protein Targeting Nucleosome Organization DNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process 'de Novo' Posttranslational Protein Folding Cellular Macromolecular Complex Assembly 'de Novo' Protein Folding Base-excision Repair DNA Methylation On Cytosine Protein Transport Protein-DNA Complex Assembly
Tagcloud ?			almost cellulose chromosome column condensation consistently cytoplasm digestion dispersed dnase eluted encode kd located locates maturation mitotic nacl nuclei onset p45 prepared presumably putative regulating regulator released sequential synthetic
Tagcloud (Difference) ?			almost cellulose chromosome column condensation consistently cytoplasm digestion dispersed dnase eluted encode kd located locates maturation mitotic nacl nuclei onset p45 prepared presumably putative regulating regulator released sequential synthetic
Tagcloud (Intersection) ?