TRMT2A and RCC1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		TRMT2A	RCC1
Description		tRNA methyltransferase 2A	regulator of chromosome condensation 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol	Chromatin Condensed Nuclear Chromosome Nucleus Nucleoplasm Chromosome Cytoplasm Protein-containing Complex
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Methyltransferase Activity C-methyltransferase Activity RNA Methyltransferase Activity Transferase Activity TRNA (uracil(54)-C5)-methyltransferase Activity, S-adenosyl Methionine-dependent	DNA Binding Chromatin Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding Small GTPase Binding Nucleosome Binding Nucleosomal DNA Binding Histone Binding Sulfate Binding Protein Heterodimerization Activity
	Biological Process	RNA Processing MRNA Processing TRNA Processing Methylation	G1/S Transition Of Mitotic Cell Cycle Mitotic Spindle Organization Chromosome Segregation Mitotic Nuclear Membrane Reassembly Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Cell Cycle Viral Process Spindle Assembly Cell Division Regulation Of Mitotic Spindle Assembly
Pathways			Rev-mediated nuclear export of HIV RNA Nuclear import of Rev protein Postmitotic nuclear pore complex (NPC) reformation
Drugs
Diseases
GWAS			Night sleep phenotypes ( 27126917) Systolic blood pressure ( 30578418)
Interacting Genes		22 interacting genes: AIMP2 ANXA7 APP APPBP2 ATP1B1 CDK4 CDKN1A GADD45G MCC MEOX2 MESD PICK1 PIK3R3 PIN1 RASA1 RCC1 SMN1 TK1 TLE5 TNFSF11 UBC ZNF837	50 interacting genes: ACTB APLP1 BAG6 CCT7 CDK1 CDK2AP2 CEBPA CHGB CHKA CSAD CSNK1A1 DDAH2 DYNC1I1 ERCC6 FAF1 FBXO7 FLAD1 GNB2 H2AC18 H2AC20 H2BC21 H3C1 HADHB HMGA1 HOXD8 KMT2B KPNA3 LRIF1 NGFR NTMT1 NUDT21 NUP98 OGT PDHB PKM PTMA RAN RANBP1 RANBP3 SDF4 SPRED1 SUMO2 TLE1 TRMT2A TUBB3 UNC119 USP4 WIZ XPO1 ZNF135
Entrez ID		27037	1104
HPRD ID		13719	01559
Ensembl ID		ENSG00000099899	ENSG00000180198
Uniprot IDs		F2Z2W7 Q8IZ69	A0A0S2Z3I4 A0A0S2Z404 P18754 Q5T081
PDB IDs		7NTN 7NTO	1A12 1I2M 5E1B 5E1D 5E1M 5E1O 5E2A 5E2B 5TBK 6DUB 8UX1
Enriched GO Terms of Interacting Partners?		Regulation Of Wnt Signaling Pathway Positive Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Regulation Of Anoikis Positive Regulation Of Apoptotic Process Regulation Of Canonical Wnt Signaling Pathway Response To Phorbol 13-acetate 12-myristate Cytoplasm Low-density Lipoprotein Particle Receptor Binding Intracellular Signaling Cassette Positive Regulation Of JNK Cascade Molecular Function Activator Activity Protein Serine/threonine Kinase Binding Regulation Of Mitotic Cell Cycle Positive Regulation Of Receptor Internalization Cell Cycle G1/S Phase Transition G1/S Transition Of Mitotic Cell Cycle	Chromatin Organization Nucleoplasm Nucleus Chromatin Remodeling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Structural Constituent Of Chromatin Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleosome Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Kinetochore Positive Regulation Of Protein Metabolic Process Regulation Of Protein Catabolic Process Protein Heterodimerization Activity Nuclear Transport Nucleocytoplasmic Transport Nuclear Pore Protein Export From Nucleus Ribosomal Large Subunit Export From Nucleus Chromosome Positive Regulation Of DNA Metabolic Process Ribosomal Small Subunit Export From Nucleus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of DNA Replication Cytosol Positive Regulation Of Proteolysis Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Nuclear Envelope Ribosomal Subunit Export From Nucleus Extracellular Exosome Nuclear Export Nuclear Export Signal Receptor Activity Protein Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Proteolysis TORC1 Signaling Positive Regulation Of TORC1 Signaling Positive Regulation Of Biosynthetic Process Nuclear Retinoic Acid Receptor Binding Pyruvate Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Protein Metabolic Process Regulation Of Protein Localization To Nucleus MRNA Cleavage And Polyadenylation Specificity Factor Complex
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