RHOH and FAM90A1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RHOH	FAM90A1
Description		ras homolog family member H	family with sequence similarity 90 member A1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Immunological Synapse Cytoplasm Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding GTPase Activity GTPase Inhibitor Activity Protein Binding GTP Binding Kinase Inhibitor Activity Protein Kinase Binding Small GTPase Binding	Protein Binding
	Biological Process	Regulation Of DNA-templated Transcription Actin Filament Organization Signal Transduction Small GTPase-mediated Signal Transduction T Cell Differentiation Negative Regulation Of Canonical NF-kappaB Signal Transduction Mast Cell Activation Positive Regulation Of T Cell Differentiation
Pathways		RHOH GTPase cycle
Drugs
Diseases
GWAS		Graves' disease ( 21841780) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Metabolite levels ( 23823483) Multiple sclerosis ( 31604244) Pre-treatment viral load in HIV-1 infection ( 31219150)	Gut microbiota (functional units) ( 27694959)
Interacting Genes		23 interacting genes: ARHGDIA ARHGDIB ARHGDIG BANP CCNH FAM90A1 GDI1 IQUB ITGB1BP1 KANK2 KCNH2 LRIF1 MBLAC1 MTX2 PLEKHA7 RIPPLY1 SCNM1 SORL1 SUOX TCF19 TGFBR1 UTP14A XPNPEP1	162 interacting genes: ABI2 ACTN3 AKAP9 AMOTL2 ANKRD23 ANKRD29 AP2M1 APP ARHGEF9 ARRDC3 BANP BCAR1 BEGAIN BLZF1 CADPS CALCOCO2 CARD9 CCDC13 CCDC57 CCN3 CCNC CCNL2 CDR2 CEP55 CEP70 CEP72 CEP76 CHRDL2 COG6 CYSRT1 DTX3 DVL2 DVL3 EFEMP2 ENKD1 EXOSC8 FAM228A FHL3 FLACC1 FLOT1 FOSB FSD2 FXR1 FXR2 FYN GABPB1 GCSAML GNPTAB GOLGA2 GOPC GPRASP3 GPSM1 GRIPAP1 HAND2 HMBOX1 HOMER3 HOMEZ HOOK2 HSF2BP ISY1 KANK2 KASH5 KIFC3 KLHL12 KPNA6 KRT31 KRT34 KRT38 KRT40 KRTAP1-1 KRTAP10-8 LDOC1 LHX6 LIMS1 LMO2 LNX1 LRP2BP LRRK2 LZTS1 LZTS2 MAD1L1 MDFI MEIS3 MID2 MIPOL1 MLH1 MORN3 MSS51 MTUS2 MYOG NBPF19 NDUFB7 NOTCH2NLA NUDT21 OVOL1 PBX1 PBX2 PDLIM7 PFDN5 PICK1 PIH1D1 PLAGL2 POF1B PPARA PPP1R13B PRDM6 PRKAR1B PRR23B PSME3 PSTPIP1 RAB11FIP2 RABEP1 RBM48 REL RHOH RINT1 ROPN1 RPRD1A SH2B2 SIAH1 SMAD3 SMARCB1 SNW1 SPRED1 SRPK2 STAC3 STMN2 STX11 TAX1BP1 TEPSIN TFIP11 TLE5 TMCC2 TRAF2 TRAF4 TRIB3 TRIM23 TRIM27 TRIM42 TRIM54 TRIM55 TRIM69 TRIM9 TRIML2 VRTN VWC2 ZBTB14 ZBTB16 ZBTB7B ZBTB8A ZC2HC1C ZMYND12 ZNF143 ZNF212 ZNF343 ZNF526 ZNF581 ZNF655 ZNF688 ZNF76 ZRANB1 ZWINT
Entrez ID		399	55138
HPRD ID		03616	07672
Ensembl ID		ENSG00000168421	ENSG00000171847
Uniprot IDs		Q15669 Q6ICP4	Q86YD7
PDB IDs
Enriched GO Terms of Interacting Partners?		Rho GDP-dissociation Inhibitor Activity GDP-dissociation Inhibitor Activity Negative Regulation Of Protein Targeting To Membrane Rho Protein Signal Transduction	Protein Binding Identical Protein Binding Zinc Ion Binding Cytoplasm Cytoskeleton Organization Regulation Of Intracellular Signal Transduction Supramolecular Fiber Organization DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Organelle Organization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Ubiquitin Protein Ligase Activity Sequence-specific DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Signal Transduction TORC1 Complex Assembly Cytoskeleton Signaling Adaptor Activity Protein Homodimerization Activity Positive Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Protein Ubiquitination Keratin Filament Positive Regulation Of Glucose Mediated Signaling Pathway Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Transcription By RNA Polymerase II Protein Kinase Binding
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