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SEPT9 and HIF1A
Number of citations of the paper that reports this interaction (PMID
16424018
)
12
Data Source:
HPRD
(in vitro, in vivo)
SEPT9
HIF1A
Gene Name
septin 9
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Stress Fiber
Cytoplasm
Microtubule
Actin Cytoskeleton
Perinuclear Region Of Cytoplasm
Nucleus
Nucleoplasm
Transcription Factor Complex
Nucleolus
Cytoplasm
Cytosol
Motile Cilium
RNA Polymerase II Transcription Factor Complex
Molecular Function
GTPase Activity
Protein Binding
GTP Binding
Transcription Factor Binding Transcription Factor Activity
RNA Polymerase II Transcription Factor Binding Transcription Factor Activity
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Sequence-specific DNA Binding Transcription Factor Activity
RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Activity
Signal Transducer Activity
Protein Binding
Transcription Factor Binding
Enzyme Binding
Protein Kinase Binding
Ubiquitin Protein Ligase Binding
Histone Acetyltransferase Binding
Nuclear Hormone Receptor Binding
Histone Deacetylase Binding
Sequence-specific DNA Binding
Protein Heterodimerization Activity
Hsp90 Protein Binding
Biological Process
Cell Cycle
Metabolic Process
Protein Heterooligomerization
Cell Division
Angiogenesis
Response To Hypoxia
Neural Crest Cell Migration
Epithelial To Mesenchymal Transition
Embryonic Placenta Development
B-1 B Cell Homeostasis
Positive Regulation Of Endothelial Cell Proliferation
Heart Looping
Positive Regulation Of Neuroblast Proliferation
Connective Tissue Replacement Involved In Inflammatory Response Wound Healing
Outflow Tract Morphogenesis
Cardiac Ventricle Morphogenesis
Lactate Metabolic Process
Regulation Of Transcription, DNA-templated
Cellular Iron Ion Homeostasis
Signal Transduction
Notch Signaling Pathway
Lactation
Visual Learning
Regulation Of Gene Expression
Vascular Endothelial Growth Factor Production
Positive Regulation Vascular Endothelial Growth Factor Production
Positive Regulation Of Epithelial Cell Migration
Positive Regulation Of Receptor Biosynthetic Process
Response To Muscle Activity
Axon Transport Of Mitochondrion
Neural Fold Elevation Formation
Cerebral Cortex Development
Negative Regulation Of Bone Mineralization
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Negative Regulation Of TOR Signaling
Oxygen Homeostasis
Positive Regulation Of Chemokine Production
Regulation Of Transforming Growth Factor Beta2 Production
Collagen Metabolic Process
Embryonic Hemopoiesis
Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Hemoglobin Biosynthetic Process
Glucose Homeostasis
MRNA Transcription From RNA Polymerase II Promoter
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Oxidative Stress
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Angiogenesis
Positive Regulation Of Glycolytic Process
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Growth
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Muscle Cell Cellular Homeostasis
Positive Regulation Of Hormone Biosynthetic Process
Digestive Tract Morphogenesis
Positive Regulation Of Nitric-oxide Synthase Activity
Cartilage Development
Elastin Metabolic Process
Intestinal Epithelial Cell Maturation
Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development
Retina Vasculature Development In Camera-type Eye
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of Chemokine-mediated Signaling Pathway
Negative Regulation Of Thymocyte Apoptotic Process
Cellular Response To Interleukin-1
Cellular Response To Hypoxia
Dopaminergic Neuron Differentiation
Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways
Signaling by NOTCH1 HD Domain Mutants in Cancer
Cellular response to hypoxia
Regulation of Hypoxia-inducible Factor (HIF) by oxygen
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Signaling by NOTCH
Regulation of gene expression by Hypoxia-inducible Factor
Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant
NOTCH1 Intracellular Domain Regulates Transcription
Oxygen-dependent asparagine hydroxylation of Hypoxia-inducible Factor Alpha
Signaling by NOTCH1
Signaling by NOTCH1 PEST Domain Mutants in Cancer
Signaling by NOTCH1 in Cancer
FBXW7 Mutants and NOTCH1 in Cancer
Drugs
Diseases
GWAS
Airflow obstruction (
22837378
)
Body mass index (
20966902
)
Protein-Protein Interactions
10 interactors:
APP
HIF1A
HNRNPD
IKBKG
NEDD4
RAB10
SEPT11
SEPT2
SEPT6
SEPT7
67 interactors:
APEX1
AR
ARNT
ARNT2
ARNTL
ATM
CDC34
CDKN2A
CITED2
COPS5
CREBBP
CSNK2A1
CTNNB1
DAP3
EGLN1
EGLN2
EGLN3
EP300
FHL2
GNB2L1
HDAC1
HDAC2
HDAC5
HIF1AN
HIF3A
HSP90AA1
HSP90AB1
JUN
MAFG
MAFK
MAPK1
MAPK3
MAX
MCM7
MDM2
MTA1
NAA10
NAA11
NCOA1
NCOA2
NDN
NR4A1
OS9
PER1
PGK1
PKM
PLD1
PSMA7
RB1
RUNX2
RWDD3
SAT1
SEPT9
SP1
SSX4
STAT3
STUB1
SUMO1
SUMO2
TP53
TRAF6
TSGA10
UBE2D1
USP19
USP20
VHL
VHLL
Entrez ID
10801
3091
HPRD ID
10360
04517
Ensembl ID
ENSG00000184640
ENSG00000100644
Uniprot IDs
Q9UHD8
A8MYV6
D0VY79
Q16665
PDB IDs
1D7G
1H2K
1H2L
1H2M
1L3E
1L8C
1LM8
1LQB
2ILM
3HQR
3HQU
4AJY
4H6J
Enriched GO Terms of Interacting Partners
?
Cell Division
Cell Morphogenesis
Neuron Differentiation
Cell Projection Organization
Intracellular Receptor Signaling Pathway
Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
B Cell Homeostasis
Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Anatomical Structure Morphogenesis
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Axon Cargo Transport
Neuromuscular Junction Development
Generation Of Neurons
Neuron Projection Development
Regulation Of DNA-templated Transcription In Response To Stress
Cell Projection Morphogenesis
Cell Part Morphogenesis
Visual Learning
Outflow Tract Morphogenesis
Neurogenesis
Response To Light Stimulus
Visual Behavior
Lymphocyte Homeostasis
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage
Neural Fold Elevation Formation
Transmission Of Virus
Basolateral Protein Localization
Development Involved In Symbiotic Interaction
Neuron Development
Cell Development
Associative Learning
Leukocyte Homeostasis
Regulation Of Synapse Structure Or Activity
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Response To Radiation
Establishment Of Localization In Cell
Synaptic Growth At Neuromuscular Junction
Elastin Metabolic Process
Regulation Of Embryonic Cell Shape
Cytokinesis
Immune System Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Establishment Of Neuroblast Polarity
Positive Regulation Of Chemokine-mediated Signaling Pathway
Vascular Endothelial Growth Factor Production
Collateral Sprouting In Absence Of Injury
Establishment Of Protein Localization To Endoplasmic Reticulum Membrane
Viral Process
Nervous System Development
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Stress
Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Positive Regulation Of Metabolic Process
Regulation Of Nitrogen Compound Metabolic Process
RNA Biosynthetic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Regulation Of Gene Expression
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Response To Stress
Cellular Metabolic Process
Cellular Response To Hypoxia
Regulation Of RNA Metabolic Process
Cellular Response To Decreased Oxygen Levels
Positive Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Cellular Biosynthetic Process
Negative Regulation Of Cellular Metabolic Process
Regulation Of Metabolic Process
Heterocycle Metabolic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cellular Response To Oxygen Levels
Gene Expression
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Gene Expression
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Macromolecule Biosynthetic Process
Cellular Response To Stimulus
Nucleobase-containing Compound Metabolic Process
Response To Abiotic Stimulus
Biosynthetic Process
Response To Organic Substance
Cellular Nitrogen Compound Metabolic Process
Response To Hypoxia
Cellular Aromatic Compound Metabolic Process
Regulation Of Signal Transduction
Negative Regulation Of Gene Expression
Response To Stimulus
Negative Regulation Of Transcription, DNA-templated
Regulation Of Protein Metabolic Process
Response To Growth Factor
Tagcloud
?
actual
ahr
analytic
atf4
becomes
datasets
hepato
lists
mechanistically
mining
modulation
nephro
nrf2
omic
ppar
precision
promise
publicly
seq
signatures
tcx
tf
tfs
thorough
toxicological
toxins
tracked
transcriptomics
xbp1
Tagcloud (Difference)
?
actual
ahr
analytic
atf4
becomes
datasets
hepato
lists
mechanistically
mining
modulation
nephro
nrf2
omic
ppar
precision
promise
publicly
seq
signatures
tcx
tf
tfs
thorough
toxicological
toxins
tracked
transcriptomics
xbp1
Tagcloud (Intersection)
?