SEPTIN9 and SEPTIN6

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (in vivo)

		SEPTIN9	SEPTIN6
Description		septin 9	septin 6
Image
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytoskeleton Microtubule Cilium Axoneme Septin Ring Actin Cytoskeleton Microtubule Cytoskeleton Septin Complex Cell Division Site Intercellular Bridge Perinuclear Region Of Cytoplasm Non-motile Cilium	Chromosome, Centromeric Region Kinetochore Chromosome Cytoplasm Spindle Cytoskeleton Cilium Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Motile Cilium Cell Division Site Cleavage Furrow Septin Collar Cell Projection Axon Terminus Sperm Annulus Presynapse
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Cadherin Binding Molecular Adaptor Activity	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Intracellular Protein Localization Actin Cytoskeleton Organization Septin Cytoskeleton Organization Cell Division Cytoskeleton-dependent Cytokinesis Positive Regulation Of Non-motile Cilium Assembly	Mitotic Cytokinesis Spermatogenesis Intracellular Protein Localization Cell Differentiation Cell Division Cytoskeleton-dependent Cytokinesis
Pathways
Drugs
Diseases		Hereditary neuralgic amyotrophy (HNA); Hereditary brachial plexus neuropathy
GWAS
Interacting Genes		21 interacting genes: APP CEBPA HIF1A HNRNPD HSF2BP IKBKG LINC00839 LINC01554 MYO1C MYO6 NEDD4 PIN1 PLK1 PTPRF RAB10 SEPTIN1 SEPTIN11 SEPTIN2 SEPTIN6 SEPTIN7 STK11	15 interacting genes: CDC42EP2 CDC42EP3 CEBPA CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1
Entrez ID		10801	23157
HPRD ID		10360	06716
Ensembl ID		ENSG00000184640	ENSG00000125354
Uniprot IDs		A0A0S2Z5A5 Q9UHD8	B1AMS2 Q14141 Q541S4 Q548C9
PDB IDs		4YQF 5CYO 5CYP	2QAG 6UPA 6WBP 7M6J
Enriched GO Terms of Interacting Partners?		Septin Ring Septin Complex Cell Division Site Cytoskeleton-dependent Cytokinesis Midbody Sperm Annulus Positive Regulation Of Catabolic Process Microtubule Cytoskeleton GTPase Activity Intracellular Protein Localization Molecular Adaptor Activity Positive Regulation Of Protein Metabolic Process GTP Binding Phosphothreonine Residue Binding Cellular Response To Stress Nucleotide Binding Cell Division Organelle Localization Phosphoserine Residue Binding Unconventional Myosin Complex Cytoskeletal Motor Activity Regulation Of Protein Metabolic Process Regulation Of Protein Localization To Nucleus Cleavage Furrow Response To Metal Ion Chromosome, Centromeric Region Kinetochore Cell Cortex Cell Projection Regulation Of Protein Localization Regulation Of Protein Catabolic Process Anoikis Positive Regulation Of Proteolysis Reproductive Process Positive Regulation Of Protein Catabolic Process Motile Cilium Intracellular Signal Transduction Protein Domain Specific Binding Stress Fiber Spindle Cellular Developmental Process Cytoplasm Cell Projection Organization Protein-containing Complex Spermatogenesis Male Gamete Generation Establishment Of Localization In Cell Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Establishment Of Organelle Localization DNA Damage Response	Regulation Of Cell Shape Cell Division Site Septin Ring Septin Complex Regulation Of Cell Morphogenesis Organelle Organization Cytoskeleton-dependent Cytokinesis Microtubule Cytoskeleton Positive Regulation Of Pseudopodium Assembly Actin Cytoskeleton Cytoskeleton Organization GTPase Activity Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Plasma Membrane Bounded Cell Projection Organization Actin Cytoskeleton Organization Regulation Of Cell Projection Organization GTP Binding Positive Regulation Of Cell Projection Organization Non-motile Cilium Actin Filament-based Process Molecular Adaptor Activity Regulation Of Anatomical Structure Morphogenesis RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Actin Filament Polymerization Cytoskeletal Regulatory Protein Binding Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Cytoskeleton Regulation Of Cell Projection Assembly Response To Vitamin B2 C/EBP Complex Helper T Cell Diapedesis Protein Phosphorylated Amino Acid Binding Response To Cholecystokinin Meiotic Metaphase Chromosome Alignment Thymidine Kinase Activity Endomembrane System Rho Protein Signal Transduction Regulation Of Cellular Component Size Actin Filament Organization Small GTPase-mediated Signal Transduction Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity CHOP-C/EBP Complex Regulation Of Stem Cell Proliferation Identical Protein Binding Regulation Of Developmental Process Cerebral Cortex Development Cerebellar Neuron Development Epithelial To Mesenchymal Transition
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