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AP4B1 and BUB1
Number of citations of the paper that reports this interaction (PMID
12419313
)
4
Data Source:
HPRD
(two hybrid)
AP4B1
BUB1
Gene Name
adaptor-related protein complex 4, beta 1 subunit
BUB1 mitotic checkpoint serine/threonine kinase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Trans-Golgi Network
Coated Pit
Clathrin Adaptor Complex
Kinetochore
Condensed Chromosome Kinetochore
Condensed Nuclear Chromosome, Centromeric Region
Nucleoplasm
Cytoplasm
Cytosol
Membrane
Molecular Function
Transporter Activity
Protein Transporter Activity
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Biological Process
Intracellular Protein Transport
Vesicle-mediated Transport
Mitotic Cell Cycle
Protein Phosphorylation
Apoptotic Process
Chromosome Segregation
Regulation Of Sister Chromatid Cohesion
Mitotic Nuclear Division
Mitotic Cell Cycle Checkpoint
Mitotic Spindle Assembly Checkpoint
Cell Proliferation
Viral Process
Cell Division
Regulation Of Chromosome Segregation
Spindle Assembly Checkpoint
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Golgi Associated Vesicle Biogenesis
trans-Golgi Network Vesicle Budding
Clathrin derived vesicle budding
Mitotic Prometaphase
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Mitotic Anaphase
Mitotic Metaphase and Anaphase
Cell Cycle, Mitotic
M Phase
Drugs
Diseases
GWAS
Breast cancer (
23535729
)
Obesity-related traits (
23251661
)
Protein-Protein Interactions
5 interactors:
AP4E1
AP4M1
BUB1
BUB1B
ZNF576
18 interactors:
AP1B1
AP2B1
AP3B1
AP4B1
APC
ARIH2
BUB1B
BUB3
CASC5
CDC20
CDK1
CRK
EIF4EBP1
HDAC1
PLK1
RAE1
RDH12
SVIL
Entrez ID
10717
699
HPRD ID
06259
03907
Ensembl ID
ENSG00000134262
ENSG00000169679
Uniprot IDs
B4DTG3
Q9Y6B7
B4DYG2
E9PC26
F5GXI5
O43683
PDB IDs
2LAH
3E7E
4A1G
Enriched GO Terms of Interacting Partners
?
Mitotic Spindle Assembly Checkpoint
Spindle Assembly Checkpoint
Mitotic Spindle Checkpoint
Negative Regulation Of Chromosome Segregation
Spindle Checkpoint
Regulation Of Mitotic Sister Chromatid Separation
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Metaphase/anaphase Transition
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of Cellular Protein Catabolic Process
Negative Regulation Of Cell Division
Regulation Of Chromosome Segregation
Negative Regulation Of Chromosome Organization
Negative Regulation Of Protein Catabolic Process
Regulation Of Mitotic Nuclear Division
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Mitotic Cell Cycle Checkpoint
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Chromosome Organization
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Cell Cycle Phase Transition
Cell Cycle Checkpoint
Regulation Of Cell Division
Cellular Protein Localization
Mitotic Nuclear Division
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Protein Localization To Kinetochore
Negative Regulation Of Proteolysis
Protein Localization To Chromosome, Centromeric Region
Negative Regulation Of Protein Processing
Regulation Of Protein Catabolic Process
Regulation Of Protein Processing
Regulation Of Mitotic Cell Cycle
Cell Division
Negative Regulation Of Cell Cycle
Regulation Of Sister Chromatid Cohesion
Golgi To Endosome Transport
Regulation Of Cell Cycle Process
Protein Localization
Protein Localization To Chromosome
Regulation Of Proteolysis
Mitotic Cell Cycle Process
Cell Proliferation
Cellular Localization
Mitotic Cell Cycle
Negative Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Spindle Assembly Checkpoint
Spindle Checkpoint
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic Cell Cycle
Mitotic Spindle Assembly Checkpoint
Mitotic Spindle Checkpoint
Negative Regulation Of Chromosome Segregation
Regulation Of Mitotic Sister Chromatid Separation
Cell Cycle Checkpoint
Negative Regulation Of Mitotic Nuclear Division
Regulation Of Mitotic Metaphase/anaphase Transition
Mitotic Cell Cycle Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Proteasomal Protein Catabolic Process
Mitotic Cell Cycle Checkpoint
Mitotic Nuclear Division
Negative Regulation Of Cellular Protein Catabolic Process
Regulation Of Chromosome Segregation
Negative Regulation Of Cell Division
Regulation Of Ubiquitin-protein Transferase Activity
Protein Localization To Chromosome
Negative Regulation Of Chromosome Organization
Regulation Of Cell Cycle
Cell Cycle
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Negative Regulation Of Mitotic Cell Cycle
Regulation Of Mitotic Cell Cycle
Cell Division
Cell Cycle Process
Negative Regulation Of Cell Cycle
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cell Division
Negative Regulation Of Protein Catabolic Process
Proteasomal Protein Catabolic Process
Regulation Of Mitotic Nuclear Division
Protein Localization To Kinetochore
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Protein Localization To Chromosome, Centromeric Region
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Cellular Protein Localization
Protein Catabolic Process
Regulation Of Protein Catabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Chromosome Organization
Regulation Of Protein Ubiquitination
Tagcloud
?
aneuploidy
apocrine
arp2
beta1
biomarker
box
broad
cytokinesis
exploring
forkhead
foxm1
inside
integrin
luminal
m1
microtubule
mitosis
mitotic
notable
partners
pip
polymerization
prolactin
proteomic
rationale
signature
silencing
talin
tubulin
Tagcloud (Difference)
?
aneuploidy
apocrine
arp2
beta1
biomarker
box
broad
cytokinesis
exploring
forkhead
foxm1
inside
integrin
luminal
m1
microtubule
mitosis
mitotic
notable
partners
pip
polymerization
prolactin
proteomic
rationale
signature
silencing
talin
tubulin
Tagcloud (Intersection)
?