AP4B1 and ZNF576

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		AP4B1	ZNF576
Gene Name		adaptor-related protein complex 4, beta 1 subunit	zinc finger protein 576
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Trans-Golgi Network Coated Pit Clathrin Adaptor Complex	Nucleus
	Molecular Function	Transporter Activity Protein Transporter Activity	Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity DNA Binding Metal Ion Binding
	Biological Process	Intracellular Protein Transport Vesicle-mediated Transport	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		Golgi Associated Vesicle Biogenesis trans-Golgi Network Vesicle Budding Clathrin derived vesicle budding
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: AP4E1 AP4M1 BUB1 BUB1B ZNF576	7 interactors: AES AP4B1 KRT15 MAPKAPK5 RARG SH3GLB1 SUOX
Entrez ID		10717	79177
HPRD ID		06259	15855
Ensembl ID		ENSG00000134262
Uniprot IDs		B4DTG3 Q9Y6B7	Q9H609
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitotic Spindle Assembly Checkpoint Spindle Assembly Checkpoint Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Spindle Checkpoint Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Regulation Of Mitotic Metaphase/anaphase Transition Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Cellular Protein Catabolic Process Negative Regulation Of Cell Division Regulation Of Chromosome Segregation Negative Regulation Of Chromosome Organization Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Nuclear Division Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Mitotic Cell Cycle Checkpoint Regulation Of Proteasomal Protein Catabolic Process Regulation Of Chromosome Organization Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Regulation Of Cell Division Cellular Protein Localization Mitotic Nuclear Division Metaphase/anaphase Transition Of Mitotic Cell Cycle Protein Localization To Kinetochore Negative Regulation Of Proteolysis Protein Localization To Chromosome, Centromeric Region Negative Regulation Of Protein Processing Regulation Of Protein Catabolic Process Regulation Of Protein Processing Regulation Of Mitotic Cell Cycle Cell Division Negative Regulation Of Cell Cycle Regulation Of Sister Chromatid Cohesion Golgi To Endosome Transport Regulation Of Cell Cycle Process Protein Localization Protein Localization To Chromosome Regulation Of Proteolysis Mitotic Cell Cycle Process Cell Proliferation Cellular Localization Mitotic Cell Cycle Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle	Growth Plate Cartilage Chondrocyte Growth Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy Positive Regulation Of Anoikis Sulfide Oxidation, Using Sulfide:quinone Oxidoreductase Growth Plate Cartilage Chondrocyte Differentiation
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