NAA10 and NAA50

Number of citations of the paper that reports this interaction (PubMedID 29754825)
64

Data Source:
BioGRID (pull down)

		NAA10	NAA50
Description		N-alpha-acetyltransferase 10, NatA catalytic subunit	N-alpha-acetyltransferase 50, NatE catalytic subunit
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex	Nucleus Nucleolus Cytoplasm Cytosol NatA Complex Extracellular Exosome
	Molecular Function	Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Binding N-acetyltransferase Activity Protein-N-terminal-alanine Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Ribosome Binding Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity	Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Binding Histone H4 Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Protein-lysine-acetyltransferase Activity Protein N-terminal-methionine Acetyltransferase Activity
	Biological Process	Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation Chromosome Organization Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Chromatin Remodeling N-terminal Protein Amino Acid Acetylation Mitotic Sister Chromatid Cohesion Establishment Of Mitotic Sister Chromatid Cohesion Post-translational Protein Modification Mitotic Sister Chromatid Cohesion, Centromeric
Pathways
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 26502338)	Prostate cancer ( 23535732)
Interacting Genes		59 interacting genes: ACOT12 BAALC BCOR CALCOCO2 CASP8AP2 CCDC106 CCDC174 CDC25A CEBPA CEP44 CFTR CREB3 CREBRF CTNNB1 DDIT4L DHX57 EHMT2 FIP1L1 GPATCH2L H4C1 HIF1A HIF1AN HSPA4 HYPK KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 MCRS1 MDM4 MEOX2 MKRN1 MRPS11 NAA15 NAA16 NAA50 NAT1 NAT2 NOXA1 PDE4DIP PGK1 PLSCR3 PPP2R3B PSME2 RAB3IP RBCK1 RCN3 RIMBP2 RPL26 SEMA3B SNX33 SSX2IP TAF7L TSEN54 UBC ZBTB14 ZNF202 ZNF655	6 interacting genes: BHLHE40 CEBPA JMJD6 NAA10 NAA15 OTX2
Entrez ID		8260	80218
HPRD ID		02056	14350
Ensembl ID		ENSG00000102030	ENSG00000121579
Uniprot IDs		B7Z9N2 P41227	E7EQ69 Q9GZZ1
PDB IDs		6C95 6C9M 6PPL 6PW9 9F1B 9F1C 9F1D 9FPZ 9FQ0	2OB0 2PSW 3TFY 4X5K 6PPL 6PW9 6WF3 6WF5 6WFG 6WFK 6WFN 6WFO 9F1B 9F1C 9F1D
Enriched GO Terms of Interacting Partners?		Acetyltransferase Activity NatA Complex Cytosol N-terminal Protein Amino Acid Acetylation Protein Binding Arylamine N-acetyltransferase Activity Nucleus Protein Acetylation	NatA Complex Lung Development N-terminal Protein Amino Acid Acetylation Acetyltransferase Activity Protein Acetylation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Ribosome Binding Histone H4R3 Demethylase Activity Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Peptidyl-lysine 5-dioxygenase Activity Histone H3R2 Demethylase Activity Oxidative RNA Demethylation Determination Of Stomach Left/right Asymmetry Determination Of Intestine Left/right Asymmetry Response To Vitamin B2 C/EBP Complex Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity CHOP-C/EBP Complex Protein N-terminal-serine Acetyltransferase Activity Negative Regulation Of Protein Homooligomerization Ciliary Inversin Compartment White Fat Cell Proliferation Oxidative RNA Demethylase Activity Protein Demethylase Activity P-TEFb Complex Binding Negative Regulation Of Protein Oligomerization Maintenance Of Animal Organ Identity DNA-binding Transcription Factor Activity Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion MRF Binding Kidney Development Determination Of Pancreatic Left/right Asymmetry Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Protein-N-terminal Amino-acid Acetyltransferase Activity Recognition Of Apoptotic Cell Convergent Extension Involved In Gastrulation Determination Of Liver Left/right Asymmetry RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of DNA-templated Transcription Response To Phenylpropanoid Regulation Of RNA Biosynthetic Process Fat Cell Proliferation Eukaryotic Initiation Factor 4E Binding Anatomical Structure Formation Involved In Morphogenesis
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