NAA10 and NAA16

Number of citations of the paper that reports this interaction (PubMedID 19480662)
38

Data Source:
HPRD (in vivo)

		NAA10	NAA16
Description		N-alpha-acetyltransferase 10, NatA catalytic subunit	N-alpha-acetyltransferase 16, NatA auxiliary subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex	Nucleus Transcription Regulator Complex Cytoplasm Cytosol NatA Complex Extracellular Exosome
	Molecular Function	Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Binding N-acetyltransferase Activity Protein-N-terminal-alanine Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Ribosome Binding Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity	Protein Binding Acetyltransferase Activator Activity Acetyltransferase Activity Ribosome Binding
	Biological Process	Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation Chromosome Organization Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	N-terminal Protein Amino Acid Acetylation Negative Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Protein Stabilization
Pathways
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 26502338)	Keratoconus ( 33649486) Systolic blood pressure ( 30224653)
Interacting Genes		59 interacting genes: ACOT12 BAALC BCOR CALCOCO2 CASP8AP2 CCDC106 CCDC174 CDC25A CEBPA CEP44 CFTR CREB3 CREBRF CTNNB1 DDIT4L DHX57 EHMT2 FIP1L1 GPATCH2L H4C1 HIF1A HIF1AN HSPA4 HYPK KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 MCRS1 MDM4 MEOX2 MKRN1 MRPS11 NAA15 NAA16 NAA50 NAT1 NAT2 NOXA1 PDE4DIP PGK1 PLSCR3 PPP2R3B PSME2 RAB3IP RBCK1 RCN3 RIMBP2 RPL26 SEMA3B SNX33 SSX2IP TAF7L TSEN54 UBC ZBTB14 ZNF202 ZNF655	5 interacting genes: NAA10 NAA11 RPL26 SH2D2A SMURF1
Entrez ID		8260	79612
HPRD ID		02056	07977
Ensembl ID		ENSG00000102030	ENSG00000172766
Uniprot IDs		B7Z9N2 P41227	A4FU51 Q6N069
PDB IDs		6C95 6C9M 6PPL 6PW9 9F1B 9F1C 9F1D 9FPZ 9FQ0
Enriched GO Terms of Interacting Partners?		Acetyltransferase Activity NatA Complex Cytosol N-terminal Protein Amino Acid Acetylation Protein Binding Arylamine N-acetyltransferase Activity Nucleus Protein Acetylation	Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein N-terminal-serine Acetyltransferase Activity NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity N-terminal Protein Amino Acid Acetylation Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Regulation Of Translation Involved In Cellular Response To UV Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Engulfment Of Target By Autophagosome Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Ultradian Rhythm Acyltransferase Activity Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion Activin Receptor Binding Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Substrate Localization To Autophagosome Internal Protein Amino Acid Acetylation NADH Dehydrogenase Activity Positive Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Maturation N-acetyltransferase Activity I-SMAD Binding Protein Targeting To Vacuole Involved In Autophagy Ectoderm Development Negative Regulation Of Activin Receptor Signaling Pathway Transforming Growth Factor Beta Receptor Binding
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