NAA10 and ACOT12

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NAA10	ACOT12
Description		N-alpha-acetyltransferase 10, NatA catalytic subunit	acyl-CoA thioesterase 12
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GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Membrane NatA Complex	Nucleoplasm Cytoplasm Cytosol Intercellular Bridge
	Molecular Function	Protein-N-terminal Amino-acid Acetyltransferase Activity Protein Binding N-acetyltransferase Activity Protein-N-terminal-alanine Acetyltransferase Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Ribosome Binding Protein N-terminal-serine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity	Acetyl-CoA Hydrolase Activity Protein Binding ATP Binding Lipid Binding Hydrolase Activity Thiolester Hydrolase Activity Identical Protein Binding Carboxylic Ester Hydrolase Activity
	Biological Process	Protein Acetylation N-terminal Protein Amino Acid Acetylation Internal Protein Amino Acid Acetylation Chromosome Organization Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric	Acetyl-CoA Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Acyl-CoA Metabolic Process
Pathways			Mitochondrial Fatty Acid Beta-Oxidation
Drugs
Diseases
GWAS		Systemic lupus erythematosus ( 26502338)	Bipolar disorder ( 31043756)
Interacting Genes		59 interacting genes: ACOT12 BAALC BCOR CALCOCO2 CASP8AP2 CCDC106 CCDC174 CDC25A CEBPA CEP44 CFTR CREB3 CREBRF CTNNB1 DDIT4L DHX57 EHMT2 FIP1L1 GPATCH2L H4C1 HIF1A HIF1AN HSPA4 HYPK KIFAP3 KRTAP10-3 KRTAP10-5 KRTAP10-6 KRTAP10-7 MCRS1 MDM4 MEOX2 MKRN1 MRPS11 NAA15 NAA16 NAA50 NAT1 NAT2 NOXA1 PDE4DIP PGK1 PLSCR3 PPP2R3B PSME2 RAB3IP RBCK1 RCN3 RIMBP2 RPL26 SEMA3B SNX33 SSX2IP TAF7L TSEN54 UBC ZBTB14 ZNF202 ZNF655	9 interacting genes: ACOT7 MEOX1 MEOX2 NAA10 NAA11 PAX5 PAX6 REL ZBTB8A
Entrez ID		8260	134526
HPRD ID		02056	16680
Ensembl ID		ENSG00000102030	ENSG00000172497
Uniprot IDs		B7Z9N2 P41227	Q8WYK0
PDB IDs		6C95 6C9M 6PPL 6PW9 9F1B 9F1C 9F1D 9FPZ 9FQ0	3B7K 4MOB 4MOC
Enriched GO Terms of Interacting Partners?		Acetyltransferase Activity NatA Complex Cytosol N-terminal Protein Amino Acid Acetylation Protein Binding Arylamine N-acetyltransferase Activity Nucleus Protein Acetylation	Protein-N-terminal-alanine Acetyltransferase Activity Protein-N-terminal-glutamate Acetyltransferase Activity Protein N-terminal-serine Acetyltransferase Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Somite Specification RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding NatA Complex Protein-N-terminal Amino-acid Acetyltransferase Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity HMG Box Domain Binding N-terminal Protein Amino Acid Acetylation Segment Specification Somite Development Sequence-specific DNA Binding Chromatin Protein Acetylation Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Embryonic Pattern Specification Regulation Of Transcription By RNA Polymerase II Forebrain-midbrain Boundary Formation Pancreatic A Cell Development Negative Regulation Of Maintenance Of Mitotic Sister Chromatid Cohesion, Centromeric Long-chain Fatty-acyl-CoA Catabolic Process Palmitic Acid Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Cerebral Cortex Development Pattern Specification Process Positive Regulation Of RNA Metabolic Process Sclerotome Development Habenula Development Pallium Development Medium-chain Fatty Acid Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Embryonic Organ Morphogenesis Regulation Of Asymmetric Cell Division Oligodendrocyte Cell Fate Specification NF-kappaB Complex Long-chain Fatty Acyl-CoA Binding Medium-chain Fatty-acyl-CoA Metabolic Process Nucleus Forebrain Dorsal/ventral Pattern Formation Regulation Of Centromeric Sister Chromatid Cohesion Negative Regulation Of Sister Chromatid Cohesion
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