TTF2 and NVL

Number of citations of the paper that reports this interaction (PMID 12927788)
7

Data Source:
BioGRID (two hybrid)

		TTF2	NVL
Gene Name		transcription termination factor, RNA polymerase II	nuclear VCP-like
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Spliceosomal Complex Cytoplasm Transcription Elongation Factor Complex	Nucleus Nucleolus Cytoplasm Mitochondrion Plasma Membrane Membrane
	Molecular Function	DNA Binding Protein Binding ATP Binding ATP-dependent Helicase Activity DNA-dependent ATPase Activity Zinc Ion Binding	ATP Binding Poly(A) RNA Binding
	Biological Process	DNA-templated Transcription, Termination Regulation Of Transcription, DNA-templated Termination Of RNA Polymerase II Transcription MRNA Processing RNA Splicing
Pathways
Drugs
Diseases
GWAS			Major depressive disorder ( 21042317)
Protein-Protein Interactions		22 interactors: CDC5L CDKL3 CLPB DCP1A DR1 DRAP1 HINFP HNRNPA1 HNRNPA2B1 KIF4A MATR3 MYB MYBL2 NVL PDCD6IP PRDX4 SKIL SMAD1 SMAD7 TACC3 TNIP1 ZSCAN1	4 interactors: CRMP1 OSGEP RPL5 TTF2
Entrez ID		8458	4931
HPRD ID		05280	03887
Ensembl ID			ENSG00000143748
Uniprot IDs		Q9UNY4	B4DF43 O15381
PDB IDs			2X8A
Enriched GO Terms of Interacting Partners?		Gene Expression Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Heterocycle Metabolic Process Transcription, DNA-templated Negative Regulation Of Gene Expression RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cell Cycle Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Cell Cycle Regulation Of Cell Cycle Regulation Of Gene Expression Cellular Metabolic Process Mitotic Spindle Assembly Regulation Of Nitrogen Compound Metabolic Process Spindle Organization Negative Regulation Of Cellular Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Dendrite Morphogenesis Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Positive Regulation Of Transcription, DNA-templated Regulation Of Cell Morphogenesis Biosynthetic Process Mitotic Spindle Organization Positive Regulation Of Neuron Projection Development MRNA Metabolic Process MRNA Splicing, Via Spliceosome Negative Regulation Of Male Germ Cell Proliferation Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Stress RNA Splicing, Via Transesterification Reactions Positive Regulation Of Dendrite Development Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway	Threonylcarbamoyladenosine Biosynthetic Process Pharynx Development Threonylcarbamoyladenosine Metabolic Process Soft Palate Development Pyrimidine Nucleobase Catabolic Process Nucleobase-containing Compound Metabolic Process Hard Palate Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process NcRNA Metabolic Process Adenosine Metabolic Process MRNA Metabolic Process Nitrogen Compound Metabolic Process Thyroid Hormone Generation Ribosomal Large Subunit Biogenesis Nucleobase-containing Small Molecule Metabolic Process Thyroid Hormone Metabolic Process Thyroid Gland Development Hair Follicle Morphogenesis Pyrimidine Nucleobase Metabolic Process Termination Of RNA Polymerase II Transcription Epidermis Morphogenesis
Tagcloud ?		away bidirectional coimmunoprecipitate cotranscriptional dcp1a dcp2 decapping edc3 elongation ends exonuclease facilitates localize nascent pause paused peaks pol premature productive redistribution seq shifted spt5 termination torpedo tss tsss xrn2	amyotrophic bioinformatics complementary converging destabilizing differently fate frontotemporal fus grn lobar localize motoneuron motoneuronal mrnas neurodegeneration nsc progranulin recognize ribonucleoprotein sets taf15 tdp ug ultimately utr utrs vegfa vps54
Tagcloud (Difference) ?		away bidirectional coimmunoprecipitate cotranscriptional dcp1a dcp2 decapping edc3 elongation ends exonuclease facilitates nascent pause paused peaks pol premature productive redistribution seq shifted spt5 termination torpedo tss tsss xrn2	amyotrophic bioinformatics complementary converging destabilizing differently fate frontotemporal fus grn lobar motoneuron motoneuronal mrnas neurodegeneration nsc progranulin recognize ribonucleoprotein sets taf15 tdp ug ultimately utr utrs vegfa vps54
Tagcloud (Intersection) ?		localize