ARL6IP5 and ARL6

Number of citations of the paper that reports this interaction (PMID 10508919)
7

Data Source:
HPRD (two hybrid)

		ARL6IP5	ARL6
Gene Name		ADP-ribosylation factor-like 6 interacting protein 5	ADP-ribosylation factor-like 6
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Cytoplasm Cytosol Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat BBSome Ciliary Membrane Extracellular Vesicular Exosome Primary Cilium
	Molecular Function	Molecular_function Protein C-terminus Binding	Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Negative Regulation Of Mitochondrial Membrane Potential L-glutamate Transport Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Apoptotic Process Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Transport	Protein Targeting To Membrane Organelle Organization Small GTPase Mediated Signal Transduction Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Melanosome Transport Cilium Assembly Fat Cell Differentiation Intermembrane Transport Protein Polymerization Protein Localization To Cilium
Pathways			Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS			Male infertility ( 19478329)
Protein-Protein Interactions		7 interactors: ARL6 CCR5 CLN8 PRAF2 RNF185 SLC1A1 VKORC1	6 interactors: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B
Entrez ID		10550	84100
HPRD ID		09303	10588
Ensembl ID		ENSG00000144746	ENSG00000113966
Uniprot IDs		O75915	Q9H0F7
PDB IDs			2H57
Enriched GO Terms of Interacting Partners?		L-glutamate Transport Dicarboxylic Acid Transport L-glutamate Import Amino Acid Import Amino Acid Transport Carboxylic Acid Transport Organic Acid Transport Organic Anion Transport Cysteine Transport Intermembrane Transport L-glutamate Uptake Involved In Synaptic Transmission Anion Transport D-aspartate Import Ion Transport Retina Development In Camera-type Eye Visual Perception Sensory Perception Of Light Stimulus Age-dependent Response To Oxidative Stress Vitamin K Metabolic Process Somatic Motor Neuron Differentiation Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Aspartate Transport Sarcoplasmic Reticulum Calcium Ion Transport Neurotransmitter Uptake Protein Localization To Cilium Peptidyl-glutamic Acid Carboxylation Dendritic Cell Chemotaxis Neurofilament Cytoskeleton Organization Camera-type Eye Development Neuromuscular Process Controlling Posture Eye Development L-glutamate Transmembrane Transport Transport Response To Cholesterol Dendritic Cell Migration Retina Layer Formation Photoreceptor Cell Maintenance Melanosome Transport Release Of Sequestered Calcium Ion Into Cytosol Pigment Granule Transport Establishment Of Melanosome Localization Quinone Metabolic Process Drug Metabolic Process Regulation Of Sequestering Of Calcium Ion Sensory Organ Development Social Behavior Intermediate Filament Cytoskeleton Organization Melanosome Localization Entry Into Host Cell Intermediate Filament-based Process	Cotranslational Protein Targeting To Membrane Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Negative Regulation Of Mitochondrial Membrane Potential Retrograde Protein Transport, ER To Cytosol
Tagcloud ?		abundantly acceptor adp belongs calmodulin ccaat chop delta2 enhances exocytic expresses histomorphometric hormones insufficiency knock knocked mineral osteoblast osteoblastic osteoblasts osteoclast osteoclastogenesis precursors prenylated rab rankl resorption ribosylation trabecular
Tagcloud (Difference) ?		abundantly acceptor adp belongs calmodulin ccaat chop delta2 enhances exocytic expresses histomorphometric hormones insufficiency knock knocked mineral osteoblast osteoblastic osteoblasts osteoclast osteoclastogenesis precursors prenylated rab rankl resorption ribosylation trabecular
Tagcloud (Intersection) ?