ARL6 and ARL6IP1

Number of citations of the paper that reports this interaction (PMID 10508919)
7

Data Source:
HPRD (two hybrid)

		ARL6	ARL6IP1
Gene Name		ADP-ribosylation factor-like 6	ADP-ribosylation factor-like 6 interacting protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat BBSome Ciliary Membrane Extracellular Vesicular Exosome Primary Cilium	Sec61 Translocon Complex Cytosol Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	Protein Binding
	Biological Process	Protein Targeting To Membrane Organelle Organization Small GTPase Mediated Signal Transduction Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Melanosome Transport Cilium Assembly Fat Cell Differentiation Intermembrane Transport Protein Polymerization Protein Localization To Cilium	Cotranslational Protein Targeting To Membrane
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Male infertility ( 19478329)
Protein-Protein Interactions		6 interactors: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B	40 interactors: ACSF2 ARL4D ARL6 C12orf10 COL4A3BP DIABLO FAM134C FBXW7 FDFT1 FXR2 GAD2 GOLPH3 GORASP2 HGS HMGCL INPP5K MTERF3 NAPB NDRG4 NUDT3 PAM16 PBX3 RAB33A RTN4 SENP2 SHMT2 SNX1 SNX10 SNX11 SNX12 SNX15 SNX3 SNX4 SPG21 SUCLA2 TFAM TUFM WIPI2 ZFYVE21 ZNF391
Entrez ID		84100	23204
HPRD ID		10588	09641
Ensembl ID		ENSG00000113966	ENSG00000170540
Uniprot IDs		Q9H0F7	B7Z6S5 F5GXP4 Q15041
PDB IDs		2H57
Enriched GO Terms of Interacting Partners?		Cotranslational Protein Targeting To Membrane Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Negative Regulation Of Mitochondrial Membrane Potential Retrograde Protein Transport, ER To Cytosol	Protein Transport Establishment Of Protein Localization Protein Localization Cellular Localization Vesicle Organization Establishment Of Localization In Cell Intracellular Transport Organelle Organization Cellular Protein Localization Intracellular Protein Transport Negative Regulation Of Early Endosome To Late Endosome Transport Mitochondrion Organization Regulation Of DNA Endoreduplication Succinate Metabolic Process Regulation Of Early Endosome To Late Endosome Transport Transport Protein Localization To Cilium Regulation Of Protein Catabolic Process Membrane Invagination Endomembrane System Organization Negative Regulation Of Intracellular Transport Cell Projection Assembly Protein Localization To Organelle Vesicle-mediated Transport Negative Regulation Of SREBP Signaling Pathway Succinyl-CoA Pathway Diphosphoinositol Polyphosphate Catabolic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Positive Regulation Of Renal Water Transport Diadenosine Polyphosphate Catabolic Process Intralumenal Vesicle Formation Membrane Organization Localization Within Membrane Protein Localization To Membrane Endoplasmic Reticulum Organization Regulation Of Vesicle-mediated Transport Inositol Phosphate Metabolic Process Negative Regulation Of Protein Transport Lamellipodium Organization Alcohol Catabolic Process Glutamate Decarboxylation To Succinate Negative Regulation Of Triglyceride Biosynthetic Process ER To Golgi Ceramide Transport Uroporphyrinogen III Biosynthetic Process Cell Adhesion Molecule Production Intermembrane Transport Endosomal Transport Protein Targeting Biosynthetic Process
Tagcloud ?			1a 2b 3c 4c cisternae elaborate elucidated envelope er exogenously harboring homology interconnected localizes organelle potency reticulon reticulons shaped shaping sheet sheets suppress suppresses tmem33 transmembrane tubular tubulation tubules
Tagcloud (Difference) ?			1a 2b 3c 4c cisternae elaborate elucidated envelope er exogenously harboring homology interconnected localizes organelle potency reticulon reticulons shaped shaping sheet sheets suppress suppresses tmem33 transmembrane tubular tubulation tubules
Tagcloud (Intersection) ?