ARL6 and ATL2

Number of citations of the paper that reports this interaction (PMID 10508919)
7

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ARL6	ATL2
Gene Name		ADP-ribosylation factor-like 6	atlastin GTPase 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Axonemal Microtubule Plasma Membrane Cilium Axoneme Membrane Membrane Coat BBSome Ciliary Membrane Extracellular Vesicular Exosome Primary Cilium	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane
	Molecular Function	Protein Binding GTP Binding Phospholipid Binding Metal Ion Binding	GTPase Activity Protein Binding GTP Binding Identical Protein Binding
	Biological Process	Protein Targeting To Membrane Organelle Organization Small GTPase Mediated Signal Transduction Determination Of Left/right Symmetry Brain Development Visual Perception Regulation Of Smoothened Signaling Pathway Retina Layer Formation Wnt Signaling Pathway Melanosome Transport Cilium Assembly Fat Cell Differentiation Intermembrane Transport Protein Polymerization Protein Localization To Cilium	ER To Golgi Vesicle-mediated Transport Endoplasmic Reticulum Organization Golgi Organization Metabolic Process Protein Homooligomerization
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS		Male infertility ( 19478329)
Protein-Protein Interactions		6 interactors: ARL6IP1 ARL6IP4 ARL6IP5 ARL6IP6 ATL2 SEC61B	1 interactors: ARL6
Entrez ID		84100	64225
HPRD ID		10588	10662
Ensembl ID		ENSG00000113966	ENSG00000119787
Uniprot IDs		Q9H0F7	Q8NHH9
PDB IDs		2H57
Enriched GO Terms of Interacting Partners?		Cotranslational Protein Targeting To Membrane Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Negative Regulation Of Mitochondrial Membrane Potential Retrograde Protein Transport, ER To Cytosol	Intermembrane Transport Protein Localization To Cilium Retina Layer Formation Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Neural Retina Development Retina Morphogenesis In Camera-type Eye Cellular Pigmentation Regulation Of Smoothened Signaling Pathway Protein Polymerization Determination Of Left/right Symmetry Determination Of Bilateral Symmetry Pigmentation Fat Cell Differentiation Camera-type Eye Morphogenesis Protein Targeting To Membrane Eye Morphogenesis Retina Development In Camera-type Eye Visual Perception Sensory Perception Of Light Stimulus Cilium Assembly Cilium Organization Establishment Of Vesicle Localization Vesicle Localization Cilium Morphogenesis Establishment Of Protein Localization To Membrane Wnt Signaling Pathway Cell Projection Assembly Establishment Of Organelle Localization Cellular Protein Complex Assembly Camera-type Eye Development Protein Localization To Membrane Eye Development Organelle Localization Protein Targeting Organelle Assembly Pattern Specification Process
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