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GLRX3 and PRKD2
Number of citations of the paper that reports this interaction (PMID
15231748
)
65
Data Source:
BioGRID
(two hybrid)
GLRX3
PRKD2
Gene Name
glutaredoxin 3
protein kinase D2
Image
Gene Ontology Annotations
Cellular Component
Cell Cortex
Z Disc
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Golgi Apparatus
Plasma Membrane
Molecular Function
Protein Kinase C Binding
Protein Binding
Electron Carrier Activity
Protein Disulfide Oxidoreductase Activity
Poly(A) RNA Binding
Metal Ion Binding
Iron-sulfur Cluster Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Kinase C Activity
Protein Binding
ATP Binding
Metal Ion Binding
Biological Process
Regulation Of The Force Of Heart Contraction
Negative Regulation Of Cardiac Muscle Hypertrophy
Cell Redox Homeostasis
Oxidation-reduction Process
Angiogenesis
Positive Regulation Of Endothelial Cell Proliferation
Protein Phosphorylation
Cell Adhesion
Cell Death
Positive Regulation Of Endothelial Cell Migration
Peptidyl-serine Phosphorylation
Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of CREB Transcription Factor Activity
Positive Regulation Of Peptidyl-serine Phosphorylation
Intracellular Signal Transduction
Cellular Response To Vascular Endothelial Growth Factor Stimulus
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Positive Regulation Of Blood Vessel Endothelial Cell Migration
Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Positive Regulation Of Angiogenesis
Positive Regulation Of Cell Adhesion
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Protein Autophosphorylation
Vascular Endothelial Growth Factor Receptor Signaling Pathway
T Cell Receptor Signaling Pathway
Positive Regulation Of T Cell Receptor Signaling Pathway
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Endothelial Tube Morphogenesis
Positive Regulation Of ERK1 And ERK2 Cascade
Protein Kinase D Signaling
Positive Regulation Of Histone Deacetylase Activity
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of DNA Biosynthetic Process
Positive Regulation Of Endothelial Cell Chemotaxis
Pathways
Drugs
Diseases
GWAS
HIV-1 susceptibility (
21160409
)
Chronic lymphocytic leukemia (
18758461
)
Protein-Protein Interactions
57 interactors:
ADAMTSL4
ALKBH3
BOLA1
CBLB
CGGBP1
CIAPIN1
EFEMP2
FAM118A
FRA10AC1
GMCL1
GRN
HEXDC
IKZF1
KRT31
KRT38
KRTAP10-1
KRTAP10-11
KRTAP10-3
KRTAP10-5
KRTAP10-8
KRTAP10-9
KRTAP13-1
KRTAP4-11
KRTAP4-12
KRTAP4-2
KRTAP4-7
KRTAP5-6
KRTAP5-9
KRTAP9-2
LCE2D
MAP3K3
MAPK6
MAPKBP1
MOXD1
NADK
NOTCH2NL
OLFM3
PCSK5
PFDN5
PLSCR1
PRKCQ
PRKCZ
PRKD2
RGS20
SOX7
STAU1
TCF4
TMEM25
TRAF1
TRIM36
TRIM42
UGP2
ZBTB44
ZNF148
ZNF426
ZNF512B
ZNF544
17 interactors:
CASK
DST
GLRX3
GORASP1
GRIP1
HDAC7
HEY1
IFNAR1
MTF2
PDLIM7
PFDN1
PSG3
RARB
RRBP1
RXRA
SNRNP70
TGOLN2
Entrez ID
10539
25865
HPRD ID
10153
09523
Ensembl ID
ENSG00000108010
ENSG00000105287
Uniprot IDs
O76003
M0QZW1
M0R2R2
Q8NCK8
Q9BZL6
PDB IDs
2DIY
2WZ9
2YAN
3ZYW
2COA
3BGM
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of NF-kappaB Transcription Factor Activity
Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Developmental Process
Positive Regulation Of Interleukin-4 Production
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of Gene Expression
Regulation Of RNA Metabolic Process
Regulation Of Interleukin-4 Production
Positive Regulation Of CD4-positive, Alpha-beta T Cell Activation
Regulation Of Cell Activation
Regulation Of T Cell Activation
Cell Death
Death
Multicellular Organismal Development
Positive Regulation Of Interleukin-2 Production
Positive Regulation Of Alpha-beta T Cell Differentiation
Positive Regulation Of Epithelial Cell Proliferation
Anatomical Structure Development
Positive Regulation Of Neutrophil Differentiation
Renin Secretion Into Blood Stream
Regulation Of Nitrogen Compound Metabolic Process
Negative Regulation Of Insulin Receptor Signaling Pathway
Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway
Regulation Of Cellular Process
Transcription, DNA-templated
Regulation Of T Cell Receptor Signaling Pathway
Embryonic Digestive Tract Development
Positive Regulation Of Immune System Process
Regulation Of Cell-cell Adhesion
Positive Regulation Of Cell Adhesion
Regulation Of Cell Adhesion
Positive Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
RNA Biosynthetic Process
Regulation Of Lymphocyte Activation
Protein Kinase D Signaling
Positive Regulation Of T-helper 2 Cell Activation
Oxidative Single-stranded DNA Demethylation
Positive Regulation Of Interleukin-13 Secretion
Positive Regulation Of Interleukin-5 Secretion
Catenin Import Into Nucleus
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition
Renal Response To Blood Flow Involved In Circulatory Renin-angiotensin Regulation Of Systemic Arterial Blood Pressure
Platelet Activation
Regulation Of Insulin Receptor Signaling Pathway
Apoptotic Process
Positive Regulation Of T Cell Activation
Positive Regulation Of Gene Expression
Regulation Of Osteoblast Differentiation
Cell Differentiation
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Cardiac Chamber Development
Developmental Process
Positive Regulation Of Transcription, DNA-templated
Retinoic Acid Receptor Signaling Pathway
Ventricular Cardiac Muscle Cell Differentiation
Cellular Response To Steroid Hormone Stimulus
Multicellular Organismal Development
Cardiac Muscle Tissue Development
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Ossification
Intracellular Receptor Signaling Pathway
Heart Development
Regulation Of Cell Differentiation
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Heart Morphogenesis
Ventricular Cardiac Muscle Tissue Morphogenesis
Glandular Epithelial Cell Differentiation
Cellular Response To Hormone Stimulus
Negative Regulation Of Transcription, DNA-templated
Ventricular Cardiac Muscle Tissue Development
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Cardiac Muscle Tissue Morphogenesis
Cardiac Septum Morphogenesis
Positive Regulation Of Cellular Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Ossification
Regulation Of RNA Metabolic Process
Muscle Tissue Morphogenesis
Muscle Organ Morphogenesis
Cardiac Ventricle Morphogenesis
Positive Regulation Of Osteoblast Differentiation
Striated Muscle Tissue Development
Negative Regulation Of Cell Differentiation
Muscle Cell Differentiation
Negative Regulation Of Gene Expression
Muscle Tissue Development
Negative Regulation Of Biosynthetic Process
Positive Regulation Of Translational Initiation By Iron
Cardiac Septum Development
Regulation Of Gene Expression
Anatomical Structure Development
Regulation Of Nitrogen Compound Metabolic Process
Vasculogenesis
Positive Regulation Of Ossification
Tagcloud
?
a172
cdk2
crt0066101
dismal
e2f1
gbm
gbm2
gli25
glioblastoma
glioma
gliomagenesis
gm133
hallmarks
hypophosphorylation
mer
multiforme
mut
p15
pkb
pkc
prb
profoundly
retinoblastoma
senescence
silencing
t98g
u251
u87mg
Tagcloud (Difference)
?
a172
cdk2
crt0066101
dismal
e2f1
gbm
gbm2
gli25
glioblastoma
glioma
gliomagenesis
gm133
hallmarks
hypophosphorylation
mer
multiforme
mut
p15
pkb
pkc
prb
profoundly
retinoblastoma
senescence
silencing
t98g
u251
u87mg
Tagcloud (Intersection)
?