PRKD2 and PSG3

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
BioGRID (two hybrid)

		PRKD2	PSG3
Description		protein kinase D2	pregnancy specific beta-1-glycoprotein 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane	Extracellular Region
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Protein Kinase C Binding Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Adaptive Immune Response Immune System Process Protein Phosphorylation Cell Adhesion Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Migration Sphingolipid Biosynthetic Process Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-8 Production Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription By RNA Polymerase II Vascular Endothelial Growth Factor Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Endothelial Tube Morphogenesis Regulation Of T Cell Apoptotic Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis	Defense Response Female Pregnancy
Pathways		Sphingolipid de novo biosynthesis	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Coronary artery disease ( 29212778) Eosinophil count ( 32888494) Heel bone mineral density ( 30598549) Post bronchodilator FEV1 ( 26634245) Primary sclerosing cholangitis ( 23603763 27992413)
Interacting Genes		17 interacting genes: CASK DST GORASP1 GRIP1 HDAC7 HEY1 IFNAR1 MTF2 PDLIM7 PFDN1 PSG3 RARB RRBP1 RXRA SNRNP70 TGOLN2 VPS26C	5 interacting genes: ATF7IP NLGN3 PRKD2 SKIL TENT5A
Entrez ID		25865	5671
HPRD ID		09523	08892
Ensembl ID		ENSG00000105287	ENSG00000221826
Uniprot IDs		Q9BZL6	Q16557
PDB IDs		2COA 3BGM 4NNX 4NNY
Enriched GO Terms of Interacting Partners?			Regulation Of Multicellular Organismal Development Positive Regulation Of Developmental Process
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