PRKD2 and GORASP1

Number of citations of the paper that reports this interaction (PubMedID 15231748)
54

Data Source:
BioGRID (two hybrid)

		PRKD2	GORASP1
Description		protein kinase D2	golgi reassembly stacking protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Plasma Membrane Membrane	Golgi Membrane Golgi Apparatus Cis-Golgi Network Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Diacylglycerol-dependent Serine/threonine Kinase Activity Protein Kinase C Binding Protein Binding ATP Binding Zinc Ion Binding Kinase Activity Transferase Activity Metal Ion Binding Protein Serine Kinase Activity	Protein Binding Metal Ion Binding
	Biological Process	Angiogenesis Positive Regulation Of Endothelial Cell Proliferation Adaptive Immune Response Immune System Process Protein Phosphorylation Cell Adhesion Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Endothelial Cell Migration Sphingolipid Biosynthetic Process Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Interleukin-2 Production Positive Regulation Of Interleukin-8 Production Intracellular Signal Transduction Cellular Response To Vascular Endothelial Growth Factor Stimulus Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Angiogenesis Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription By RNA Polymerase II Vascular Endothelial Growth Factor Receptor Signaling Pathway T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Endothelial Tube Morphogenesis Regulation Of T Cell Apoptotic Process Positive Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of DNA Biosynthetic Process Positive Regulation Of Endothelial Cell Chemotaxis	Protein N-linked Glycosylation Golgi Organization Protein Transport Negative Regulation Of Dendrite Morphogenesis Establishment Of Protein Localization To Plasma Membrane Golgi Ribbon Formation
Pathways		Sphingolipid de novo biosynthesis	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport
Drugs
Diseases
GWAS		Aspartate aminotransferase levels ( 33547301) Chronic lymphocytic leukemia ( 18758461 28165464) Coronary artery disease ( 29212778) Eosinophil count ( 32888494) Heel bone mineral density ( 30598549) Post bronchodilator FEV1 ( 26634245) Primary sclerosing cholangitis ( 23603763 27992413)	Social communication problems ( 24564958)
Interacting Genes		17 interacting genes: CASK DST GORASP1 GRIP1 HDAC7 HEY1 IFNAR1 MTF2 PDLIM7 PFDN1 PSG3 RARB RRBP1 RXRA SNRNP70 TGOLN2 VPS26C	17 interacting genes: AGPS CASP3 CASP7 CDK1 GOLGA2 HIPK3 LONRF1 MAPK6 NEFL PLK1 PRKD2 RPS6KA1 SCRN1 TGFA TMED2 TMED3 TRAF4
Entrez ID		25865	64689
HPRD ID		09523	06038
Ensembl ID		ENSG00000105287	ENSG00000114745
Uniprot IDs		Q9BZL6	A0A8Q3SHU6 A0A8Q3WL08 B3KPY8 B4E1H8 Q9BQQ3
PDB IDs		2COA 3BGM 4NNX 4NNY	4REY 6G8T 6G8W
Enriched GO Terms of Interacting Partners?			Protein Serine Kinase Activity Golgi Organization Protein Phosphorylation Phosphorylation Protein Serine/threonine Kinase Activity Regulation Of Synaptic Vesicle Cycle Protein Kinase Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Kinase Activity Protein Modification Process Cellular Response To Staurosporine COPII-coated ER To Golgi Transport Vesicle Regulation Of Apoptotic Process Golgi Disassembly Regulation Of Programmed Cell Death Centrosome Cycle Hepatocyte Proliferation G2/M Transition Of Mitotic Cell Cycle Protein Metabolic Process Cell Cycle G2/M Phase Transition Potassium Channel Inhibitor Activity Golgi Cisterna Membrane Fibroblast Apoptotic Process Mitotic Nuclear Membrane Disassembly Transferase Activity Intracellular Signal Transduction Nuclear Membrane Disassembly Microtubule Organizing Center Organization Membrane Disassembly COPI-coated Vesicle Membrane Protein Kinase Binding Cytoplasm Protein Poly-ADP-ribosylation Aspartic-type Endopeptidase Activity Neuron Apoptotic Process Peptidyl-threonine Phosphorylation Execution Phase Of Apoptosis Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Protein Localization To Site Of Double-strand Break Microtubule Cytoskeleton Organization Involved In Mitosis Apoptotic Process Programmed Cell Death Cell Death Mitotic Cell Cycle Phase Transition Mitotic G2 DNA Damage Checkpoint Signaling Phosphate-containing Compound Metabolic Process Cellular Response To Alkaloid ATP Binding Chromosome Condensation Cell Cycle Phase Transition
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