SH2D3A and CENPB

Number of citations of the paper that reports this interaction (PubMedID 25814554)
62

Data Source:
BioGRID (two hybrid)

		SH2D3A	CENPB
Description		SH2 domain containing 3A	centromere protein B
Image		No pdb structure
GO Annotations	Cellular Component		Chromosome, Centromeric Region Condensed Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Pericentric Heterochromatin Nuclear Body
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Protein Binding	Nucleic Acid Binding DNA Binding Chromatin Binding Satellite DNA Binding Protein Binding Centromeric DNA Binding Sequence-specific DNA Binding
	Biological Process	JNK Cascade Small GTPase-mediated Signal Transduction
Pathways
Drugs
Diseases
GWAS
Interacting Genes		7 interacting genes: BCAR1 CENPB EGFR ERBB2 ERBB3 GAB1 NXF1	20 interacting genes: ADRB2 ANXA7 APP CDKN1A CENPW FBXO25 GADD45A GFI1B GSK3B HAND2 NR3C1 PARP1 PARP2 PIN1 RPS6KA6 SH2D3A SMN1 TAC1 TADA3 TK1
Entrez ID		10045	1059
HPRD ID		05283	00314
Ensembl ID		ENSG00000125731	ENSG00000125817
Uniprot IDs		A8K2M8 Q9BRG2	P07199
PDB IDs			1BW6 1HLV 1UFI 6KDR
Enriched GO Terms of Interacting Partners?		Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Enzyme-linked Receptor Protein Signaling Pathway ERBB2 Signaling Pathway ERBB3:ERBB2 Complex Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway ErbB-3 Class Receptor Binding Basal Plasma Membrane ERBB2-EGFR Signaling Pathway ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Protein Tyrosine Kinase Activator Activity Protein Tyrosine Kinase Activity Schwann Cell Development Peripheral Nervous System Development Receptor Complex Positive Regulation Of Epithelial Cell Proliferation Cell Surface Receptor Signaling Pathway Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Transmembrane Signaling Receptor Activity Basolateral Plasma Membrane Growth Factor Binding Cellular Response To Epidermal Growth Factor Stimulus Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Activity Response To Epidermal Growth Factor Cellular Response To Growth Factor Stimulus Animal Organ Development Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cell Cycle G1/S Phase Transition Response To Growth Factor Multivesicular Body, Internal Vesicle Lumen Regulation Of Angiogenesis Glial Cell Development Ribonucleoside-diphosphate Reductase Activity Regulation Of Vasculature Development Wound Healing Neuron Differentiation Cell Migration Insulin Receptor Signaling Pathway Regulation Of Epithelial Cell Proliferation Positive Regulation Of Mitotic Cell Cycle Phase Transition Regulation Of Cell Growth Ruffle Membrane Focal Adhesion Shc-EGFR Complex Myelination Axon Ensheathment Positive Regulation Of Cardiac Muscle Tissue Development	Cellular Response To Amyloid-beta Response To Amyloid-beta NAD+-protein-serine ADP-ribosyltransferase Activity Neuronal Dense Core Vesicle DNA ADP-ribosylation NAD DNA ADP-ribosyltransferase Activity Nucleus Positive Regulation Of Cardiac Muscle Hypertrophy Cellular Response To Nerve Growth Factor Stimulus Response To Nerve Growth Factor Chromatin Organization Regulation Of Developmental Process Positive Regulation Of Programmed Cell Death Regulation Of System Process Regulation Of Protein Localization To Nucleus Regulation Of Multicellular Organismal Process Regulation Of Developmental Growth Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Protein Auto-ADP-ribosylation Negative Regulation Of Macromolecule Metabolic Process Signal Transduction Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Neuron Apoptotic Process Antifungal Humoral Response Positive Regulation Of Reactive Oxygen Species Metabolic Process Negative Regulation Of Developmental Process Regulation Of Cardiac Muscle Hypertrophy NAD+-protein-glutamate ADP-ribosyltransferase Activity Regulation Of MAPK Cascade Negative Regulation Of Macromolecule Biosynthetic Process NAD+-protein-aspartate ADP-ribosyltransferase Activity Negative Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Intracellular Signal Transduction Regulation Of Membrane Potential Response To Yeast Positive Regulation Of CAMP/PKA Signal Transduction Regulation Of Cell Cycle Regulation Of Muscle System Process Protein Poly-ADP-ribosylation Regulation Of Neuron Apoptotic Process Regulation Of Transcription By RNA Polymerase II Response To Lipid NAD+-protein Mono-ADP-ribosyltransferase Activity Regulation Of Mitotic Cell Cycle Negative Regulation Of Systemic Arterial Blood Pressure
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?