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EMG1 and KHDRBS1
Number of citations of the paper that reports this interaction (PMID
16169070
)
531
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
EMG1
KHDRBS1
Gene Name
EMG1 N1-specific pseudouridine methyltransferase
KH domain containing, RNA binding, signal transduction associated 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleolus
Cytoplasm
Nucleus
Nucleoplasm
Cytoplasm
Membrane
Grb2-Sos Complex
Molecular Function
RNA Binding
RRNA Binding
Poly(A) RNA Binding
RRNA (pseudouridine) Methyltransferase Activity
DNA Binding
RNA Binding
SH3/SH2 Adaptor Activity
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
SH3 Domain Binding
Protein Complex Binding
Identical Protein Binding
Poly(A) RNA Binding
Biological Process
RRNA Processing
RRNA Methylation
Ribosomal Small Subunit Biogenesis
G2/M Transition Of Mitotic Cell Cycle
Transcription, DNA-templated
MRNA Processing
Cell Cycle Arrest
Signal Transduction
Cell Surface Receptor Signaling Pathway
Cell Proliferation
Positive Regulation Of Signal Transduction
Regulation Of Protein Stability
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Translational Initiation
Regulation Of RNA Export From Nucleus
Positive Regulation Of RNA Export From Nucleus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
11 interactors:
ANXA3
APP
CTSE
FAM74A4
HIVEP1
IL7R
KHDRBS1
NAT6
PSMB7
PSME1
SLC25A38
109 interactors:
ABI2
ACTB
AGO1
AHI1
AMPH
APBB1
ARHGEF4
ARHGEF9
AZIN1
BAIAP2L1
BTK
BZRAP1
CBL
CD2AP
CDK1
CIRBP
CREB3L3
CREBBP
CRK
CRKL
CSK
DDX5
DHX9
DLG1
DLG2
DLG3
DLG4
DNMBP
DOCK2
DOCK3
EFEMP1
EMG1
FGR
FNBP4
FRK
FYN
GAS7
GPHN
GRAP
GRAP2
GRB2
HCK
HNRNPK
INSR
ITK
ITSN1
ITSN2
JAK3
KHDRBS3
LCK
LYN
MAPK1
MIA2
MPP6
MYO1C
MYO7A
NCF1
NCK1
NCK2
NCKIPSD
NPHP1
OSTF1
PACSIN1
PIK3R1
PIK3R3
PLCG1
PLCG2
POT1
PPP1R13B
PRMT1
PSTPIP1
PTBP2
PTK6
PTPN6
RALY
RAPSN
RASA1
RBFOX2
RBM7
RBMX
RUSC2
SASH1
SCG5
SH3PXD2A
SH3YL1
SKAP2
SMAD2
SMARCA2
SNX30
SNX9
SORBS1
SPATA13
SRC
SSFA2
STAT3
STUB1
TBL1X
TJP1
TNFSF11
TUBB3
U2AF2
UBA52
UBASH3B
VAV1
WBP4
YES1
YTHDC1
ZBTB7A
ZDHHC6
Entrez ID
10436
10657
HPRD ID
12803
03926
Ensembl ID
ENSG00000126749
ENSG00000121774
Uniprot IDs
Q92979
Q07666
PDB IDs
2XA6
3QHE
Enriched GO Terms of Interacting Partners
?
Immune System Process
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Process
Antigen Processing And Presentation Of Peptide Antigen
Regulation Of Cell Cycle Phase Transition
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle
Antigen Processing And Presentation
Negative Regulation Of Catalytic Activity
Positive Regulation Of Proteolysis
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest
Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Signal Transduction Involved In DNA Damage Checkpoint
Signal Transduction Involved In Cell Cycle Checkpoint
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Cell Cycle
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Mitotic G1 DNA Damage Checkpoint
Positive Regulation Of Ubiquitin-protein Transferase Activity
Mitotic G1/S Transition Checkpoint
G1 DNA Damage Checkpoint
Positive Regulation Of Cell Cycle Arrest
Positive Regulation Of Ligase Activity
Regulation Of Cellular Amino Acid Metabolic Process
DNA Damage Response, Signal Transduction By P53 Class Mediator
Regulation Of Mitotic Cell Cycle
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Ubiquitin-protein Transferase Activity
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Signal Transduction In Response To DNA Damage
Mitotic DNA Damage Checkpoint
Negative Regulation Of Cell Cycle
Regulation Of Cell Cycle Arrest
Positive Regulation Of Cellular Protein Metabolic Process
Mitotic DNA Integrity Checkpoint
Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Protein Ubiquitination
Interleukin-7-mediated Signaling Pathway
Positive Regulation Of RNA Export From Nucleus
Synaptic Growth At Neuromuscular Junction
Negative Regulation Of Cellular Metabolic Process
Regulation Of Cell Cycle Process
Regulation Of Cellular Ketone Metabolic Process
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Signal Transduction By P53 Class Mediator
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Fc Receptor Signaling Pathway
Signaling
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Cell Communication
Peptidyl-tyrosine Autophosphorylation
Innate Immune Response
Signal Transduction
Immune Response-regulating Signaling Pathway
Immune Response
Endocytosis
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc Receptor Mediated Stimulatory Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Locomotion
Movement Of Cell Or Subcellular Component
Cellular Response To Stimulus
Positive Regulation Of Metabolic Process
Cell Surface Receptor Signaling Pathway
Defense Response
Positive Regulation Of Immune Response
Regulation Of Immune System Process
Cellular Response To Peptide Hormone Stimulus
Neurotrophin TRK Receptor Signaling Pathway
Phagocytosis
Cellular Response To Peptide
Positive Regulation Of Immune System Process
Neurotrophin Signaling Pathway
Positive Regulation Of Signal Transduction
Cellular Response To Growth Factor Stimulus
Regulation Of Immune Response
Epidermal Growth Factor Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Response To Growth Factor
Antigen Receptor-mediated Signaling Pathway
Cell Differentiation
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Peptidyl-tyrosine Phosphorylation
Regulation Of Cellular Component Organization
Immune System Process
Response To Stimulus
Regulation Of Signaling
Cell Projection Organization
Intracellular Signal Transduction
Cellular Response To Organic Substance
Regulation Of Metabolic Process
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