EMG1 and FAM74A4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		EMG1	FAM74A4
Gene Name		EMG1 N1-specific pseudouridine methyltransferase	family with sequence similarity 74, member A4
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm
	Molecular Function	RNA Binding RRNA Binding Poly(A) RNA Binding RRNA (pseudouridine) Methyltransferase Activity
	Biological Process	RRNA Processing RRNA Methylation Ribosomal Small Subunit Biogenesis
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ANXA3 APP CTSE FAM74A4 HIVEP1 IL7R KHDRBS1 NAT6 PSMB7 PSME1 SLC25A38	26 interactors: CCDC85B CCNDBP1 CEP44 EFEMP2 EMG1 HMBOX1 IKZF1 KRT31 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 KRTAP5-9 LZTS2 MEOX2 MTUS2 NOTCH2NL PDE4DIP PHC2 RPGRIP1 STX11 TCF4 TMCC2
Entrez ID		10436	401508
HPRD ID		12803	16982
Ensembl ID		ENSG00000126749	ENSG00000229746
Uniprot IDs		Q92979
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune System Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Antigen Processing And Presentation Negative Regulation Of Catalytic Activity Positive Regulation Of Proteolysis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity Regulation Of Cellular Amino Acid Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Protein Metabolic Process Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Ubiquitination Interleukin-7-mediated Signaling Pathway Positive Regulation Of RNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Signal Transduction By P53 Class Mediator Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I
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