EMG1 and ANXA3

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		EMG1	ANXA3
Gene Name		EMG1 N1-specific pseudouridine methyltransferase	annexin A3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm	Cytoplasm Plasma Membrane Membrane Phagocytic Vesicle Membrane Specific Granule Extracellular Vesicular Exosome
	Molecular Function	RNA Binding RRNA Binding Poly(A) RNA Binding RRNA (pseudouridine) Methyltransferase Activity	Calcium Ion Binding Calcium-dependent Phospholipid Binding Phospholipase A2 Inhibitor Activity Calcium-dependent Protein Binding
	Biological Process	RRNA Processing RRNA Methylation Ribosomal Small Subunit Biogenesis	Phagocytosis Positive Regulation Of Endothelial Cell Migration Defense Response To Bacterium Negative Regulation Of Catalytic Activity Neutrophil Degranulation Positive Regulation Of Angiogenesis Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS			Non-albumin protein levels ( 22558069) Rheumatoid arthritis ( 22446963)
Protein-Protein Interactions		11 interactors: ANXA3 APP CTSE FAM74A4 HIVEP1 IL7R KHDRBS1 NAT6 PSMB7 PSME1 SLC25A38	6 interactors: EMG1 IGSF21 REG3A TP53 UBR1 UNC119
Entrez ID		10436	306
HPRD ID		12803	00111
Ensembl ID		ENSG00000126749	ENSG00000138772
Uniprot IDs		Q92979	P12429
PDB IDs			1AII 1AXN
Enriched GO Terms of Interacting Partners?		Immune System Process Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Process Antigen Processing And Presentation Of Peptide Antigen Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Antigen Processing And Presentation Negative Regulation Of Catalytic Activity Positive Regulation Of Proteolysis Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Cell Cycle Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity Regulation Of Cellular Amino Acid Metabolic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Mitotic Cell Cycle Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Signal Transduction In Response To DNA Damage Mitotic DNA Damage Checkpoint Negative Regulation Of Cell Cycle Regulation Of Cell Cycle Arrest Positive Regulation Of Cellular Protein Metabolic Process Mitotic DNA Integrity Checkpoint Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Ubiquitination Interleukin-7-mediated Signaling Pathway Positive Regulation Of RNA Export From Nucleus Synaptic Growth At Neuromuscular Junction Negative Regulation Of Cellular Metabolic Process Regulation Of Cell Cycle Process Regulation Of Cellular Ketone Metabolic Process Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Signal Transduction By P53 Class Mediator Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I	Negative Regulation Of Clathrin-mediated Endocytosis Negative Regulation Of Macromitophagy Cellular Response To Leucine Negative Regulation Of Caveolin-mediated Endocytosis Oligodendrocyte Apoptotic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Cytokinesis, Completion Of Separation Negative Regulation Of Helicase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Cell Aging Positive Regulation Of Thymocyte Apoptotic Process Negative Regulation Of Keratinocyte Differentiation Regulation Of Caveolin-mediated Endocytosis Mitochondrial DNA Repair Response To Leucine Positive Regulation Of Keratinocyte Proliferation Mitotic Cytokinetic Process Regulation Of Mitochondrion Degradation T Cell Proliferation Involved In Immune Response B Cell Lineage Commitment Glial Cell Apoptotic Process Oxidative Stress-induced Premature Senescence Response To Light Stimulus Negative Regulation Of Epidermal Cell Differentiation ER Overload Response Negative Regulation Of Macroautophagy Stress-induced Premature Senescence Regulation Of Clathrin-mediated Endocytosis Positive Regulation Of T Cell Apoptotic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator DNA Strand Renaturation Regulation Of Cellular Amino Acid Metabolic Process DNA Damage Response, Signal Transduction Resulting In Transcription Mitotic Cell Cycle Arrest Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Thymocyte Apoptotic Process RRNA Methylation Response To Radiation Replicative Senescence Positive Regulation Of Mitochondrial Membrane Permeability Determination Of Adult Lifespan Positive Regulation Of Lymphocyte Apoptotic Process Circadian Behavior RRNA Modification Mitochondrial DNA Metabolic Process Positive Regulation Of Histone Deacetylation Cell Separation After Cytokinesis Rhythmic Behavior Lipoprotein Transport Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Tagcloud ?			1e 3e 7e accessed adam28 adenocarcinomas cabig cadm1 ccne1 cd24 cdk1 cdkn2a com datasets demonstration ercc1 geo kmplot logrank online opn plot plotted rad51 repositories silico tcga uni www
Tagcloud (Difference) ?			1e 3e 7e accessed adam28 adenocarcinomas cabig cadm1 ccne1 cd24 cdk1 cdkn2a com datasets demonstration ercc1 geo kmplot logrank online opn plot plotted rad51 repositories silico tcga uni www
Tagcloud (Intersection) ?