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MYOT and TRIM55
Number of citations of the paper that reports this interaction (PMID
18157088
)
41
Data Source:
BioGRID
(two hybrid)
MYOT
TRIM55
Gene Name
myotilin
tripartite motif containing 55
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Actin Cytoskeleton
Z Disc
Sarcolemma
Nucleus
Cytoplasm
Microtubule
Molecular Function
Actin Binding
Protein Binding
Structural Constituent Of Muscle
Alpha-actinin Binding
Signal Transducer Activity
Zinc Ion Binding
Identical Protein Binding
Biological Process
Muscle Contraction
Signal Transduction
Pathways
Drugs
Diseases
GWAS
Heart rate (
23583979
)
Response to statin therapy (
22666496
)
Protein-Protein Interactions
12 interactors:
ACTN1
APP
AXIN1
FLNA
FLNC
GPRASP2
LRP12
NME7
ST7
TFG
TRIM55
TRIM63
61 interactors:
ACTA1
ANKRD1
ATP5B
ATXN3
ATXN3L
BRAP
CKM
DCAF6
DES
EEF1G
EHHADH
EIF3E
ESPL1
FHL2
FLNA
FLNB
FLNC
GFM1
GMEB1
LMCD1
MDM4
MRPL19
MRPL41
MYBPC1
MYBPC3
MYOT
MYOZ1
NDUFA1
NEB
NEBL
NOMO1
OTUB1
OTUB2
PCGF1
PIAS1
PIAS2
PIAS3
RNF114
SQSTM1
STAM
TCAP
TNNI1
TNNI2
TNNI3
TRIM27
TRIM54
TRIM63
TTN
UBE2D1
UBE2D2
UBE2D3
UCHL3
UCHL5
USP13
USP28
USP4
USP5
USP7
USP8
UXT
YOD1
Entrez ID
9499
84675
HPRD ID
04981
05927
Ensembl ID
ENSG00000120729
ENSG00000147573
Uniprot IDs
B4DT68
Q9UBF9
Q9BYV6
PDB IDs
2KDG
2KKQ
Enriched GO Terms of Interacting Partners
?
Platelet Degranulation
Actin Crosslink Formation
Signal Transduction
Signaling
Platelet Activation
Cell Junction Assembly
Cell Communication
Response To Stimulus
Receptor Clustering
Vesicle-mediated Transport
Microtubule-based Process
Cellular Response To Stimulus
Exocytosis
Wnt-activated Signaling Pathway Involved In Forebrain Neuron Fate Commitment
Canonical Wnt Signaling Pathway Involved In Neural Plate Anterior/posterior Pattern Formation
Blood Coagulation
Hemostasis
Synaptic Growth At Neuromuscular Junction
Cellular Component Assembly
Determination Of Left/right Symmetry
Establishment Of Localization In Cell
Determination Of Bilateral Symmetry
Collateral Sprouting In Absence Of Injury
Axial Mesoderm Formation
Secretion By Cell
Microtubule-based Transport
Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation
Protein Localization To Tight Junction
Cytoskeleton-dependent Intracellular Transport
Regulation Of Body Fluid Levels
Neural Plate Anterior/posterior Regionalization
Ciliary Receptor Clustering Involved In Smoothened Signaling Pathway
Collateral Sprouting
Axon Midline Choice Point Recognition
Wound Healing
Regulation Of Growth
Transport
Secretion
Skeletal Muscle Atrophy
Smooth Endoplasmic Reticulum Calcium Ion Homeostasis
Axial Mesoderm Morphogenesis
Olfactory Placode Formation
Regulation Of Protein Import Into Nucleus
Muscle Cell Development
Cellular Localization
Endocytosis
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Striated Muscle Atrophy
Axon Choice Point Recognition
Cell Activation
Actin-myosin Filament Sliding
Muscle Filament Sliding
Actin-mediated Cell Contraction
Protein Deubiquitination
Protein Modification By Small Protein Removal
Actin Filament-based Movement
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Muscle Contraction
Actin Filament-based Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Muscle System Process
Protein K48-linked Deubiquitination
Cellular Macromolecule Catabolic Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of Protein Catabolic Process
Striated Muscle Cell Development
Cellular Protein Metabolic Process
Muscle Structure Development
Muscle Cell Development
Protein K63-linked Deubiquitination
Myofibril Assembly
Proteolysis
Cellular Protein Modification Process
Striated Muscle Tissue Development
Cardiac Muscle Tissue Morphogenesis
Striated Muscle Cell Differentiation
Muscle Tissue Development
Muscle Tissue Morphogenesis
Actomyosin Structure Organization
Muscle Organ Morphogenesis
Cardiac Muscle Tissue Development
Protein Metabolic Process
Muscle Organ Development
Protein Modification By Small Protein Conjugation
Muscle Cell Differentiation
Myosin Filament Assembly
Catabolic Process
Actin Cytoskeleton Organization
Skeletal Muscle Thin Filament Assembly
Cytoskeleton Organization
Skeletal Myofibril Assembly
Response To Muscle Stretch
Heart Morphogenesis
Striated Muscle Contraction
Cellular Process
Tagcloud
?
bag3
causative
cryab
desmin
disorganizations
dnajb6
encode
fhl1
flnc
focal
hereditary
hmerf
hyaline
inclusions
mfm
muscles
myofibril
myofibrillar
myopathy
name
pathologically
pathomechanisms
quite
spheroid
summarized
ttn
unexpectedly
vcp
zasp
Tagcloud (Difference)
?
bag3
causative
cryab
desmin
disorganizations
dnajb6
encode
fhl1
flnc
focal
hereditary
hmerf
hyaline
inclusions
mfm
muscles
myofibril
myofibrillar
myopathy
name
pathologically
pathomechanisms
quite
spheroid
summarized
ttn
unexpectedly
vcp
zasp
Tagcloud (Intersection)
?