NADSYN1 and MYO15B

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid, two hybrid)

		NADSYN1	MYO15B
Gene Name		NAD synthetase 1	myosin XVB pseudogene
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	NAD+ Synthase (glutamine-hydrolyzing) Activity ATP Binding Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds
	Biological Process	Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process NAD Biosynthetic Process NAD Metabolic Process Small Molecule Metabolic Process
Pathways		Metabolism of vitamins and cofactors Defective GIF causes intrinsic factor deficiency Defective CD320 causes methylmalonic aciduria Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMAA causes methylmalonic aciduria type cblA Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Nicotinate metabolism Defects in vitamin and cofactor metabolism Defects in cobalamin (B12) metabolism
Drugs
Diseases
GWAS		Vitamin D insufficiency ( 20541252) Vitamin D levels ( 20418485)
Protein-Protein Interactions		3 interactors: CUTC MYO15B UPF1	14 interactors: AES CCDC36 CEP57L1 DNAJA3 FAM9B GFAP NADSYN1 NUP62 PNMA5 RAD54B RUNDC3A SSSCA1 TRIM29 ZBTB8A
Entrez ID		55191	80022
HPRD ID		16309
Ensembl ID		ENSG00000172890	ENSG00000266714
Uniprot IDs		B3KUU4 Q6IA69
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone MRNA Catabolic Process Dosage Compensation By Inactivation Of X Chromosome Regulation Of Translational Termination Dosage Compensation Histone MRNA Metabolic Process Copper Ion Homeostasis Copper Ion Transport
Tagcloud ?		asip atm casp8 ccnd1 color cyp2r1 dark eye firstly gwas irf4 kaspar lately lentigines mc1r mx2 oca2 parp1 penetrance pigmentation predisposition rs12203592 rs1485993 rs1801516 rs3219090 slc45a2 spanish try works
Tagcloud (Difference) ?		asip atm casp8 ccnd1 color cyp2r1 dark eye firstly gwas irf4 kaspar lately lentigines mc1r mx2 oca2 parp1 penetrance pigmentation predisposition rs12203592 rs1485993 rs1801516 rs3219090 slc45a2 spanish try works
Tagcloud (Intersection) ?