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CCNO and ITSN1
Number of citations of the paper that reports this interaction (PMID
18654987
)
7
Data Source:
BioGRID
(two hybrid)
CCNO
ITSN1
Gene Name
cyclin O
intersectin 1 (SH3 domain protein)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Cytoplasm
Cytosol
Plasma Membrane
Coated Pit
Lamellipodium
Cell Junction
Endocytic Vesicle
Neuron Projection
Synapse
Molecular Function
Uracil DNA N-glycosylase Activity
Guanyl-nucleotide Exchange Factor Activity
Rho Guanyl-nucleotide Exchange Factor Activity
Calcium Ion Binding
Protein Binding
Kinase Activator Activity
Protein Complex Scaffold
Proline-rich Region Binding
Biological Process
Base-excision Repair
Cell Cycle
Cilium Assembly
Response To Drug
Cell Division
Multi-ciliated Epithelial Cell Differentiation
Small GTPase Mediated Signal Transduction
Axon Guidance
Positive Regulation Of Rho GTPase Activity
Positive Regulation Of Phosphorylation
Positive Regulation Of Apoptotic Process
Negative Regulation Of Neuron Apoptotic Process
Positive Regulation Of GTPase Activity
Neurotrophin TRK Receptor Signaling Pathway
Ephrin Receptor Signaling Pathway
Synaptic Vesicle Endocytosis
Regulation Of Small GTPase Mediated Signal Transduction
Positive Regulation Of Protein Kinase B Signaling
Apoptotic Signaling Pathway
Pathways
Base Excision Repair
Depyrimidination
Resolution of AP sites via the multiple-nucleotide patch replacement pathway
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Removal of DNA patch containing abasic residue
Base-Excision Repair, AP Site Formation
Resolution of AP sites via the single-nucleotide replacement pathway
Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
Displacement of DNA glycosylase by APE1
Resolution of Abasic Sites (AP sites)
Signaling by GPCR
Signalling by NGF
Axon guidance
Cell death signalling via NRAGE, NRIF and NADE
p75 NTR receptor-mediated signalling
Rho GTPase cycle
EPHB-mediated forward signaling
GPCR downstream signaling
NRAGE signals death through JNK
Signaling by Rho GTPases
EPH-Ephrin signaling
G alpha (12/13) signalling events
Drugs
Diseases
GWAS
Protein-Protein Interactions
4 interactors:
ITSN1
PCNA
RPA2
VAV2
82 interactors:
AGFG1
AGFG2
AP2B1
ARF6
ARFIP2
ARHGAP31
ASAP2
CCNO
CDC42
CEP85L
CLIP2
CLTC
CSNK2B
CYTH1
DAB2
DES
DISC1
DLGAP1
DNM1
DNM2
EEF1A1
EPHB2
EPN2
EPS15
EPS15L1
FCHSD2
FNBP1
FNBP4
GAREML
GCC1
GOLGA5
HIP1
HRAS
ITSN2
KHDRBS1
KIF16B
KIF5A
LMO4
MAPK6
MAPK8IP2
MRPL20
MTUS2
PACSIN3
PDCD6IP
PFDN5
PICALM
PIK3AP1
PIK3C2B
PIK3R1
PLK1
PPFIA2
PPL
PREX1
RAB11FIP2
RAB5A
RABEP1
RAI14
RNF40
RPS6KA5
SCAMP1
SCOC
SF3B4
SH3GL2
SMARCC2
SNAP23
SNAP25
SNX5
SOS1
SPDL1
SPRY2
STON2
SYNJ1
SYNJ2
TK1
TRIM8
TSG101
UBE2K
UNC119
WASL
WBP11
ZAK
ZFPM2
Entrez ID
10309
6453
HPRD ID
06375
03898
Ensembl ID
ENSG00000152669
ENSG00000205726
Uniprot IDs
P22674
A7XZY7
F8W7U0
Q15811
Q6PD56
PDB IDs
1KI1
2KGR
2KHN
3FIA
3QBV
4IIM
Enriched GO Terms of Interacting Partners
?
Nucleotide-excision Repair, DNA Gap Filling
Telomere Maintenance Via Semi-conservative Replication
Nuclear DNA Replication
Telomere Maintenance Via Recombination
Mitotic Recombination
DNA Strand Elongation Involved In DNA Replication
DNA Strand Elongation
Telomere Maintenance Via Telomere Lengthening
Transcription-coupled Nucleotide-excision Repair
Mismatch Repair
Base-excision Repair
Telomere Maintenance
Nucleotide-excision Repair
Ephrin Receptor Signaling Pathway
DNA-dependent DNA Replication
Positive Regulation Of Deoxyribonuclease Activity
G1/S Transition Of Mitotic Cell Cycle
Leading Strand Elongation
Positive Regulation Of Hydrolase Activity
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
DNA Recombination
Positive Regulation Of Rho GTPase Activity
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
DNA Recombinase Assembly
Regulation Of Rho GTPase Activity
DNA Replication
Positive Regulation Of Catalytic Activity
Regulation Of Rho Protein Signal Transduction
Apoptotic Signaling Pathway
Axon Guidance
Translesion Synthesis
Positive Regulation Of Ras GTPase Activity
Regulation Of DNA Damage Checkpoint
Regulation Of Double-strand Break Repair Via Homologous Recombination
Axonogenesis
Regulation Of Ras GTPase Activity
Nucleotide-excision Repair, DNA Damage Removal
Axon Development
Cellular Response To Growth Factor Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Positive Regulation Of Apoptotic Process
Postreplication Repair
Positive Regulation Of Programmed Cell Death
DNA Repair
Chemotaxis
Response To Growth Factor
Regulation Of Transcription Involved In G1/S Transition Of Mitotic Cell Cycle
Regulation Of Catalytic Activity
Vesicle-mediated Transport
Endocytosis
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Regulation Of Endocytosis
Vesicle Organization
Cellular Localization
Establishment Of Localization In Cell
Regulation Of Vesicle-mediated Transport
Signaling
Synaptic Transmission
Regulation Of Cellular Component Organization
Establishment Of Organelle Localization
Cell Communication
Regulation Of Signaling
Organelle Organization
Protein Localization
Cell Differentiation
Synaptic Vesicle Transport
Cell-cell Signaling
Membrane Budding
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Organelle Localization
Regulation Of ERBB Signaling Pathway
Positive Regulation Of Metabolic Process
Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Neuron Projection Morphogenesis
Negative Regulation Of ERBB Signaling Pathway
Post-Golgi Vesicle-mediated Transport
Establishment Of Vesicle Localization
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Vesicle Localization
Transport
Cell Morphogenesis Involved In Neuron Differentiation
Axon Guidance
Generation Of Neurons
Cell Morphogenesis Involved In Differentiation
Membrane Organization
Cell Projection Morphogenesis
Cell Part Morphogenesis
Establishment Of Protein Localization
Cell Projection Organization
Synaptic Vesicle Recycling
Axonogenesis
Cellular Protein Complex Assembly
Neurogenesis
Regulation Of Catalytic Activity
Regulation Of Signal Transduction
Intracellular Transport
Cell Morphogenesis
Tagcloud
?
cbr1
david
degs
downloaded
dyrk1a
egr1
encyclopedia
geo
gse
hmgn1
hypergeometric
interrogate
kegg
kyoto
macromolecular
multiarray
mycmax
mzf1
nfe2
nfy
olf1
ominibus
pax5
rma
rp58
son
srebp1
tmem50b
ttc3
Tagcloud (Difference)
?
cbr1
david
degs
downloaded
dyrk1a
egr1
encyclopedia
geo
gse
hmgn1
hypergeometric
interrogate
kegg
kyoto
macromolecular
multiarray
mycmax
mzf1
nfe2
nfy
olf1
ominibus
pax5
rma
rp58
son
srebp1
tmem50b
ttc3
Tagcloud (Intersection)
?