NET1 and MAGI1

Number of citations of the paper that reports this interaction (PubMedID 11350080)
0

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		NET1	MAGI1
Description		neuroepithelial cell transforming 1	membrane associated guanylate kinase, WW and PDZ domain containing 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Plasma Membrane Cell-cell Junction Adherens Junction Bicellular Tight Junction Membrane Cell Junction Cell Projection Anchoring Junction Cell Periphery
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding	Nucleotide Binding Protein Binding ATP Binding Alpha-actinin Binding
	Biological Process	Regulation Of Cell Growth Signal Transduction Positive Regulation Of Rho Protein Signal Transduction Intracellular Signal Transduction Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction Myoblast Migration Cellular Response To Hydrogen Peroxide Cellular Response To Ionizing Radiation	Endothelial Cell Morphogenesis Cell Adhesion Signal Transduction Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell-cell Adhesion Protein-containing Complex Assembly
Pathways		NRAGE signals death through JNK G alpha (12/13) signalling events RHOA GTPase cycle RHOB GTPase cycle
Drugs
Diseases
GWAS			Adolescent idiopathic scoliosis ( 28334814) Asthma ( 27611488) Asthma (childhood onset) ( 27611488) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cirrhosis (alcohol related) ( 32853455) Cobalt levels ( 26025379) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Cortical surface area (MOSTest) ( 32665545) Crohn's disease-related phenotypes ( 25557950) Declining hemoglobin trajectory in blood donors ( 33491795) Homeostasis model assessment of beta-cell function (dietary factor interaction) ( 24204828) Knee osteoarthritis ( 28916551) Neurociticism ( 29500382) Neuroticism ( 25993607) Nicotine dependence symptom count ( 25555482) Ocular sarcoidosis ( 32141793) Ocular sarcoidosis in sarcoidosis ( 32141793) Post bronchodilator FEV1/FVC ratio ( 26634245) PR interval ( 23534349) Pre-treatment viral load in HIV-1 infection ( 31219150) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Tinnitus ( 33742053)
Interacting Genes		3 interacting genes: MAGI1 NCK2 RHOA	27 interacting genes: ACTN4 ADGRB1 AMOT ASIC3 ATF6 ATN1 CLCN5 CRHR1 CTNNB1 DAG1 GBP2 IGSF5 IL6R LPP LRP2 NET1 RAC1 RASA1 RASL11B RPS6KA1 RPS6KA2 RPS6KA3 SYNPO TFAP2A TP53BP2 WBP1 WBP2
Entrez ID		10276	9223
HPRD ID		07342	04020
Ensembl ID		ENSG00000173848	ENSG00000151276
Uniprot IDs		Q5SQI5 Q5SQI7 Q7Z628	Q96QZ7
PDB IDs		3EO2 4XH9	1WBP 2KPK 2KPL 2Q9V 2R4H 2YSD 2YSE 2ZAJ 3BPU 5N7D 5N7F 5N7G 6TWU 6TWX 6TWY 7P71
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Cell-cell Adhesion Regulation Of Cell Adhesion Cell Morphogenesis T Cell Selection Positive Regulation Of T Cell Activation Positive Regulation Of Leukocyte Cell-cell Adhesion Positive Regulation Of Lymphocyte Activation Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Leukocyte Cell-cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Cell Activation Angiotensin-mediated Vasoconstriction Involved In Regulation Of Systemic Arterial Blood Pressure Cell Periphery Cell Surface Receptor Signaling Pathway Mitotic Cleavage Furrow Formation Regulation Of Cellular Response To X-ray Negative Regulation Of Glial Cell-derived Neurotrophic Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Type IV Hypersensitivity Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Involved In Ureteric Bud Formation Negative Regulation Of Cell Proliferation Involved In Mesonephros Development Epithelial Tube Morphogenesis Positive Regulation Of T Cell Differentiation Regulation Of Alpha-beta T Cell Activation Positive Regulation Of Lymphocyte Differentiation Aortic Valve Formation Positive Regulation Of Vascular Associated Smooth Muscle Contraction Neuron Migration Endothelial Tube Lumen Extension Skeletal Muscle Satellite Cell Migration Pro-T Cell Differentiation Parathyroid Hormone Secretion Cell Migration Kidney Development Positive Regulation Of Supramolecular Fiber Organization Cell Fate Commitment Positive Regulation Of Immune System Process Beta Selection Positive Regulation Of Leukocyte Differentiation Positive Regulation Of Cytoskeleton Organization Regulation Of Endothelial Cell Migration Bone Trabecula Morphogenesis Cell Junction Regulation Of T Cell Differentiation Positive Regulation Of Protein-containing Complex Assembly Cell Motility Nephric Duct Formation Regulation Of Thyroid Hormone Generation	Anchoring Junction Ribosomal Protein S6 Kinase Activity Intracellular Signal Transduction Regulation Of Apoptotic Process Regulation Of Programmed Cell Death Stress Fiber Trans-synaptic Signaling Synaptic Signaling Positive Regulation Of Developmental Process Engulfment Of Apoptotic Cell Focal Adhesion Bicellular Tight Junction Regulation Of Cell Communication Regulation Of Signaling Synapse Regulation Of Synapse Organization Tube Morphogenesis Regulation Of Intracellular Signal Transduction Chemical Synaptic Transmission Positive Regulation Of Actin Filament Bundle Assembly TORC1 Signaling Signal Transduction Regulation Of Cellular Component Organization Midbrain Dopaminergic Neuron Differentiation Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Vasculogenesis Animal Organ Development Glutamatergic Synapse Lamellipodium Forebrain Development Cell Junction Regulation Of Signal Transduction Cell-cell Signaling TOR Signaling Gastrulation With Mouth Forming Second Regulation Of Cell-substrate Adhesion Apical Part Of Cell Enzyme Binding Cranial Skeletal System Development Anatomical Structure Arrangement Signaling Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Stress Fiber Assembly Cell Communication Epithelial Tube Branching Involved In Lung Morphogenesis Regulation Of Gliogenesis Blood Vessel Morphogenesis Regulation Of Translation In Response To Stress Cell-matrix Adhesion
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