NET1

Gene Name		neuroepithelial cell transforming 1
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Gene Ontology Annotations	Cellular Component	Nucleus Cytosol Plasma Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Rho Guanyl-nucleotide Exchange Factor Activity GTP-Rho Binding
	Biological Process	Regulation Of Cell Growth Signal Transduction Small GTPase Mediated Signal Transduction Positive Regulation Of Rho GTPase Activity Positive Regulation Of Apoptotic Process Neurotrophin TRK Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction Myoblast Migration Cellular Response To Hydrogen Peroxide Cellular Response To Ionizing Radiation Apoptotic Signaling Pathway Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Pathways		Rho GTPase cycle Signaling by GPCR GPCR downstream signaling Signalling by NGF Cell death signalling via NRAGE, NRIF and NADE Signaling by Rho GTPases NRAGE signals death through JNK G alpha (12/13) signalling events p75 NTR receptor-mediated signalling
Drugs
Diseases
GWAS
Protein-protein Interactions		2 interactors: MAGI1 RHOA
Entrez ID		10276
HPRD ID		07342
Ensembl ID		ENSG00000173848
Uniprot IDs		Q5SQI5 Q5SQI7 Q7Z628
PDB IDs		3EO2
Enriched GO Terms of Interacting Partners?		Skeletal Muscle Satellite Cell Migration Apolipoprotein A-I-mediated Signaling Pathway Cleavage Furrow Formation Positive Regulation Of Transport Ossification Involved In Bone Maturation Bone Maturation Negative Chemotaxis Mitotic Spindle Assembly Positive Regulation Of NF-kappaB Import Into Nucleus Protein Complex Assembly Regulation Of Osteoblast Proliferation Negative Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of Sodium Ion Transport Substantia Nigra Development Wound Healing, Spreading Of Cells Positive Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Cytokinesis Regulation Of NF-kappaB Import Into Nucleus Mitotic Spindle Organization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Actin Filament Bundle Assembly Trabecula Morphogenesis Neural Nucleus Development Negative Regulation Of ERK1 And ERK2 Cascade Regulation Of Cytokinesis Rho Protein Signal Transduction Morphogenesis Of An Epithelial Sheet Negative Regulation Of Axonogenesis Regulation Of Stress Fiber Assembly Neuron Death Regulation Of Sodium Ion Transport Regulation Of Intracellular Signal Transduction Apical Junction Assembly Positive Regulation Of Axonogenesis Cellular Component Assembly Spindle Assembly Midbrain Development Regulation Of Transcription Factor Import Into Nucleus Positive Regulation Of Protein Import Into Nucleus Ephrin Receptor Signaling Pathway Negative Regulation Of Cell Morphogenesis Involved In Differentiation Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Peptidyl-serine Phosphorylation Cytokinesis Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Cell-cell Junction Assembly Negative Regulation Of Neuron Projection Development Spindle Organization Positive Regulation Of Cell Division
Tagcloud ?		alleviation bivalent cdc14 condensin copurified csm1 demethylase demethylates distinctly fork hypercondensed jarid1 jhd2 lrs4 lys36 lys4 lys79 mislocalized nts nts1 nucleolar periphery rdna rent rfb silencing sir2 telophase tof2