CYTH4 and KRT16

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYTH4	KRT16
Description		cytohesin 4	keratin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Membrane Centriolar Satellite Intercellular Bridge	Cornified Envelope Nucleus Cytosol Cytoskeleton Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Regulation Of ARF Protein Signal Transduction	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Intermediate Filament Organization Keratinocyte Migration Establishment Of Skin Barrier
Pathways		Intra-Golgi traffic	Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex Non-epidermolytic palmoplantar keratoderma (NEPPK)
GWAS		Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Uterine fibroids ( 28836065)
Interacting Genes		23 interacting genes: AMOTL2 CBY2 CCDC197 CCDC6 CNKSR1 CTAG1A CTAG1B FOS FOSB HOOK2 KANK2 KIFC3 KRT15 KRT16 KRT34 KRT40 PCM1 PSMB1 SNAPC5 SNCA SYCE1L TRIM54 USHBP1	53 interacting genes: AIRIM AMOT ARFIP2 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 DRC4 EPM2AIP1 GNG10 HGS KIFC3 KLC4 KRT1 KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT77 KRT78 KRT79 KRT8 KRT80 KRT81 KRT82 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1
Entrez ID		27128	3868
HPRD ID		07354	01018
Ensembl ID		ENSG00000100055	ENSG00000186832
Uniprot IDs		B4E2V8 Q9UIA0	P08779
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Cytoskeleton Organization Organelle Organization Intermediate Filament Structural Molecule Activity Response To Corticosterone Behavioral Response To Cocaine TRNA Threonylcarbamoyladenosine Metabolic Process Identical Protein Binding Microtubule Binding Structural Constituent Of Cytoskeleton Response To Progesterone Response To Mineralocorticoid Medium-term Memory Cellular Response To Prolactin Epidermis Development Morphogenesis Of An Epithelium Epithelial Cell Migration Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Negative Regulation Of Supramolecular Fiber Organization Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Response To Cocaine Cytoplasmic Vesicle Membrane Cellular Response To Metal Ion Negative Regulation Of Microtubule Polymerization Or Depolymerization	Intermediate Filament Organization Keratin Filament Structural Constituent Of Skin Epidermis Keratinization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Intermediate Filament Supramolecular Fiber Organization Cytoskeleton Organization Organelle Organization Protein Binding Cytosol
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?