CYTH4 and SYCE1L

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CYTH4	SYCE1L
Description		cytohesin 4	synaptonemal complex central element protein 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Membrane Centriolar Satellite Intercellular Bridge	Synaptonemal Complex Intermediate Filament Cytoskeleton
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction	Synaptonemal Complex Assembly Meiotic Cell Cycle Synaptonemal Complex Organization
Pathways		Intra-Golgi traffic
Drugs
Diseases
GWAS		Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Uterine fibroids ( 28836065)	Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Type 2 diabetes (age of onset) ( 28060188)
Interacting Genes		23 interacting genes: AMOTL2 CBY2 CCDC197 CCDC6 CNKSR1 CTAG1A CTAG1B FOS FOSB HOOK2 KANK2 KIFC3 KRT15 KRT16 KRT34 KRT40 PCM1 PSMB1 SNAPC5 SNCA SYCE1L TRIM54 USHBP1	36 interacting genes: ALDH18A1 ANKRD36 ATF5 BFSP2 BOLL C1orf216 C22orf39 CALN1 CCDC146 CCDC196 CCHCR1 CENPP CST1 CYTH4 DPPA3 EPC1 FGA HSF2BP KCNIP2 KIAA1328 LCA5L LNX1 MED10 NOL4 NTAQ1 ODF1 OIP5 PFDN5 SCHIP1 SLC7A8 SMARCD1 SPHKAP SRSF10 TNNI1 TRAPPC13 ZNF526
Entrez ID		27128	100130958
HPRD ID		07354
Ensembl ID		ENSG00000100055	ENSG00000205078
Uniprot IDs		B4E2V8 Q9UIA0	A8MT33
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Cytoskeleton Organization Organelle Organization Intermediate Filament Structural Molecule Activity Response To Corticosterone Behavioral Response To Cocaine TRNA Threonylcarbamoyladenosine Metabolic Process Identical Protein Binding Microtubule Binding Structural Constituent Of Cytoskeleton Response To Progesterone Response To Mineralocorticoid Medium-term Memory Cellular Response To Prolactin Epidermis Development Morphogenesis Of An Epithelium Epithelial Cell Migration Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Negative Regulation Of Supramolecular Fiber Organization Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Response To Cocaine Cytoplasmic Vesicle Membrane Cellular Response To Metal Ion Negative Regulation Of Microtubule Polymerization Or Depolymerization
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