CYTH4

Description		cytohesin 4
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytosol Plasma Membrane Membrane Centriolar Satellite Intercellular Bridge
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Lipid Binding
	Biological Process	Regulation Of ARF Protein Signal Transduction
Pathways		Intra-Golgi traffic
Drugs
Diseases
GWAS		Response to methotrexate in juvenile idiopathic arthritis ( 24709693) Uterine fibroids ( 28836065)
Novel Interacting Genes		1 novel interacting genes: AP1B1
Interacting Genes		23 interacting genes: AMOTL2 CBY2 CCDC197 CCDC6 CNKSR1 CTAG1A CTAG1B FOS FOSB HOOK2 KANK2 KIFC3 KRT15 KRT16 KRT34 KRT40 PCM1 PSMB1 SNAPC5 SNCA SYCE1L TRIM54 USHBP1
Entrez ID		27128
HPRD ID		07354
Ensembl ID		ENSG00000100055
Uniprot IDs		B4E2V8 Q9UIA0
PDB IDs
Enriched GO Terms of Interacting Partners?		Structural Constituent Of Skin Epidermis Supramolecular Fiber Organization Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Cytoskeleton Cytoskeleton Organization Organelle Organization Intermediate Filament Structural Molecule Activity Response To Corticosterone Behavioral Response To Cocaine TRNA Threonylcarbamoyladenosine Metabolic Process Identical Protein Binding Microtubule Binding Structural Constituent Of Cytoskeleton Response To Progesterone Response To Mineralocorticoid Medium-term Memory Cellular Response To Prolactin Epidermis Development Morphogenesis Of An Epithelium Epithelial Cell Migration Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Negative Regulation Of Supramolecular Fiber Organization Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Cytoskeleton Organization Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Response To Cocaine Cytoplasmic Vesicle Membrane Cellular Response To Metal Ion Negative Regulation Of Microtubule Polymerization Or Depolymerization
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