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PSME3 and PFDN5
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid, two hybrid)
PSME3
PFDN5
Description
proteasome activator subunit 3
prefoldin subunit 5
Image
GO Annotations
Cellular Component
Proteasome Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cilium
Proteasome Activator Complex
Membrane
Ciliary Basal Body
Nucleus
Cytoplasm
Cytosol
Prefoldin Complex
Protein-containing Complex
Intermediate Filament Cytoskeleton
Molecular Function
P53 Binding
Protein Binding
Identical Protein Binding
Endopeptidase Activator Activity
MDM2/MDM4 Family Protein Binding
Amyloid-beta Binding
Transcription Corepressor Activity
Protein Binding
Unfolded Protein Binding
Biological Process
Apoptotic Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Regulation Of DNA-templated Transcription
Protein Folding
Negative Regulation Of DNA-templated Transcription
Retina Development In Camera-type Eye
Negative Regulation Of Canonical Wnt Signaling Pathway
Negative Regulation Of Amyloid Fibril Formation
RNA Polymerase I Assembly
RNA Polymerase II Core Complex Assembly
RNA Polymerase III Assembly
Pathways
Proteasome assembly
Prefoldin mediated transfer of substrate to CCT/TriC
Drugs
Diseases
GWAS
Interacting Genes
63 interacting genes:
ABCF3
ADAP1
AICDA
ATN1
ATP5F1B
BBS2
CASP3
CASP6
CASP7
CDC25B
CDC42
CEBPA
CHEK2
COIL
CREBBP
DEPTOR
DIP2A
DMRT3
DTNBP1
DVL3
EAF1
EAF2
FAM90A1
FBXL12
FMR1
FOXD4L1
FXR1
FXR2
GPATCH2L
HSPA5
INPP5J
ITPKB
KANSL1
KBTBD7
KLF2
LNX1
MDM2
MEOX2
NCOA3
NTAQ1
NUDT18
PFDN5
PICK1
PRKAB2
PRR13
RDX
RNF111
RPH3AL
RPS27
SERF2
SIRT1
SMURF1
SPG7
TBXA2R
THAP10
TNFAIP8L1
TP53
TXN2
UBE2H
UBE2I
WDR25
YWHAQ
ZCCHC10
113 interacting genes:
ABI2
ANKRD55
ATOSB
BCAS2
BCL6
BHLHE40
BRMS1
C10orf55
C10orf62
C22orf39
CALCOCO2
CCDC198
CEBPA
CIMIP1
CSPP1
DMRT3
DOK4
DOK5
EEIG1
ELK3
ESPNL
FAAP20
FAM110A
FAM221A
FAM222B
FAM90A1
GLRX3
GLYCTK
GPANK1
GSTO2
GUCD1
HAPLN2
HHEX
HOXB9
HOXC8
IKBKG
IKZF3
IL16
INCA1
IRX2
IRX6
ITSN1
KCTD9
KDM1A
KLHL38
KLHL42
LARP4
LNX1
MAP2K5
METTL21A
MISP
MRPL45
MYC
MYOT
MYOZ1
NEUROG2
NOXA1
NTAQ1
PATZ1
PAX9
PFDN6
PHF1
PHF24
PILRA
PITX1
PITX2
POGZ
PRKAB2
PRPF18
PRR35
PSMB4
PSMB8
PSME3
RIBC1
RIPPLY1
RSRC2
RUSC1
SAXO1
SAXO4
SCNM1
SDCBP
SHISA6
SLAIN1
SMAP1
SMG9
SNAI1
SNRNP25
SNRPB
SOHLH1
SPAG8
SPG21
SPMIP2
SPMIP4
SYCE1L
SYT17
TAF6L
TBX3
TCF19
TFG
TLE5
TP73
TRAPPC6A
TRIM28
TUBA1B
TUBA3C
VAX2
VEZF1
VGLL1
WDR25
WHR1
YPEL5
ZC2HC1C
ZNF148
Entrez ID
10197
5204
HPRD ID
05500
05359
Ensembl ID
ENSG00000131467
ENSG00000123349
Uniprot IDs
B3KQ25
P61289
V9HWJ8
Q99471
PDB IDs
7YQC
7YQD
6NR8
6NR9
6NRB
6NRC
6NRD
7WU7
Enriched GO Terms of Interacting Partners
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Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
Cellular Response To Staurosporine
Response To Nutrient Levels
Protein Binding
Protein Domain Specific Binding
Nucleus
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Cellular Response To Nutrient Levels
Macromolecule Catabolic Process
Cytosol
Positive Regulation Of Protein Metabolic Process
Cellular Response To Alkaloid
Post-translational Protein Modification
Response To Xenobiotic Stimulus
Neuron Projection
Response To Alkaloid
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Leukocyte Apoptotic Process
Response To UV
Proteolysis
Regulation Of Protein Metabolic Process
Signal Transduction By P53 Class Mediator
Mononuclear Cell Differentiation
Protein-containing Complex
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Translation Regulator Activity
Cellular Response To Glucose Starvation
Cellular Response To Actinomycin D
Positive Regulation Of Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cytoplasm
Developmental Process
Modification-dependent Protein Catabolic Process
PML Body
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of RNA Metabolic Process
Protein Destabilization
Response To Actinomycin D
HLH Domain Binding
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Protein Stability
Leukocyte Differentiation
Protein Catabolic Process
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of MiRNA-mediated Gene Silencing
Disordered Domain Specific Binding
Glial Cell Apoptotic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Protein Binding
Negative Regulation Of Transcription By RNA Polymerase II
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of Transcription By RNA Polymerase II
Chromatin
Negative Regulation Of RNA Metabolic Process
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Nucleus
DNA-binding Transcription Factor Activity
Sequence-specific DNA Binding
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
DNA Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
Sequence-specific Double-stranded DNA Binding
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
DNA-binding Transcription Factor Binding
Positive Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II-specific DNA-binding Transcription Factor Binding
Positive Regulation Of RNA Metabolic Process
Pattern Specification Process
MRF Binding
Regionalization
Regulation Of RNA Metabolic Process
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
E-box Binding
Axonemal A Tubule Inner Sheath
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