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PSME3 and HSPA5
Number of citations of the paper that reports this interaction (PubMedID
16169070
)
0
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
PSME3
HSPA5
Description
proteasome activator subunit 3
heat shock protein family A (Hsp70) member 5
Image
GO Annotations
Cellular Component
Proteasome Complex
Nucleus
Nucleoplasm
Cytoplasm
Cytosol
Cilium
Proteasome Activator Complex
Membrane
Ciliary Basal Body
Nucleus
Cytoplasm
Mitochondrion
Endoplasmic Reticulum
Endoplasmic Reticulum Lumen
Endoplasmic Reticulum Membrane
Endoplasmic Reticulum-Golgi Intermediate Compartment
Cytosol
Plasma Membrane
Focal Adhesion
COP9 Signalosome
Cell Surface
Membrane
Midbody
Protein-containing Complex
Endoplasmic Reticulum Chaperone Complex
Melanosome
Intracellular Membrane-bounded Organelle
Extracellular Exosome
Molecular Function
P53 Binding
Protein Binding
Identical Protein Binding
Endopeptidase Activator Activity
MDM2/MDM4 Family Protein Binding
Nucleotide Binding
Calcium Ion Binding
Protein Binding
ATP Binding
Hydrolase Activity
ATP Hydrolysis Activity
Enzyme Binding
Protein Domain Specific Binding
Protein Serine/threonine Kinase Inhibitor Activity
Heat Shock Protein Binding
Ubiquitin Protein Ligase Binding
Ribosome Binding
Protein Folding Chaperone
Cadherin Binding
Unfolded Protein Binding
Protein-folding Chaperone Binding
Misfolded Protein Binding
ATP-dependent Protein Folding Chaperone
Biological Process
Apoptotic Process
Regulation Of Proteasomal Protein Catabolic Process
Regulation Of G1/S Transition Of Mitotic Cell Cycle
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Translational Initiation
Protein Folding
ER Overload Response
Cerebellum Structural Organization
Cerebellar Purkinje Cell Layer Development
Substantia Nigra Development
Positive Regulation Of Cell Migration
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Endoplasmic Reticulum Unfolded Protein Response
Post-translational Protein Targeting To Membrane, Translocation
Negative Regulation Of Protein-containing Complex Assembly
Positive Regulation Of Protein Ubiquitination
Protein Folding In Endoplasmic Reticulum
Response To Endoplasmic Reticulum Stress
Maintenance Of Protein Localization In Endoplasmic Reticulum
IRE1-mediated Unfolded Protein Response
PERK-mediated Unfolded Protein Response
ERAD Pathway
Protein Refolding
Cellular Response To Glucose Starvation
Negative Regulation Of Apoptotic Process
Positive Regulation Of Transcription By RNA Polymerase II
Proteolysis Involved In Protein Catabolic Process
Regulation Of Protein Folding In Endoplasmic Reticulum
Cellular Response To Interleukin-4
Regulation Of ATF6-mediated Unfolded Protein Response
Regulation Of IRE1-mediated Unfolded Protein Response
Negative Regulation Of IRE1-mediated Unfolded Protein Response
Regulation Of PERK-mediated Unfolded Protein Response
Negative Regulation Of PERK-mediated Unfolded Protein Response
Pathways
Proteasome assembly
Platelet degranulation
Regulation of HSF1-mediated heat shock response
ATF6 (ATF6-alpha) activates chaperones
PERK regulates gene expression
IRE1alpha activates chaperones
ATF6 (ATF6-alpha) activates chaperone genes
ATF6B (ATF6-beta) activates chaperones
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Antigen Presentation: Folding, assembly and peptide loading of class I MHC
Modulation of host responses by IFN-stimulated genes
Drugs
Antihemophilic factor, human recombinant
Acetylsalicylic acid
Copper
Lonoctocog alfa
Moroctocog alfa
Diseases
GWAS
Refractive error (
32231278
)
Smoking initiation (
33082346
)
Interacting Genes
63 interacting genes:
ABCF3
ADAP1
AICDA
ATN1
ATP5F1B
BBS2
CASP3
CASP6
CASP7
CDC25B
CDC42
CEBPA
CHEK2
COIL
CREBBP
DEPTOR
DIP2A
DMRT3
DTNBP1
DVL3
EAF1
EAF2
FAM90A1
FBXL12
FMR1
FOXD4L1
FXR1
FXR2
GPATCH2L
HSPA5
INPP5J
ITPKB
KANSL1
KBTBD7
KLF2
LNX1
MDM2
MEOX2
NCOA3
NTAQ1
NUDT18
PFDN5
PICK1
PRKAB2
PRR13
RDX
RNF111
RPH3AL
RPS27
SERF2
SIRT1
SMURF1
SPG7
TBXA2R
THAP10
TNFAIP8L1
TP53
TXN2
UBE2H
UBE2I
WDR25
YWHAQ
ZCCHC10
77 interacting genes:
A2M
AGO4
APC
APOB
BAG3
BCAR1
CASP7
CDK7
CPT1A
DDX24
DNAJC1
DNAJC10
DPH1
DPYSL5
EIF2AK3
ERBB2
ERCC6
ERN1
ERP29
F8
FCHSD2
FNDC3B
GRIA1
HLA-C
HMGB1
HSPBP1
HTR3A
IGHM
KRT14
KRT18
KRT8
LCT
LDLR
LINC01554
MATK
METTL21A
MTNR1A
MTNR1B
NDRG1
NEDD4L
NRIP1
OTUD3
PARK7
PAWR
PCSK7
PRDM14
PRNP
PSME3
PTPN11
PTPRF
RIPK4
RNF114
RNF26
RPN1
SEC61A1
SEC63
SERPINB5
SH3BP4
SIL1
SIRPA
SQSTM1
SREBF2
STMN1
SUMO2
SUMO4
TCERG1
TG
TMEM132A
TMEM62
TRA
TSHR
UBE3A
UBQLN4
VHL
VWF
XAF1
YWHAB
Entrez ID
10197
3309
HPRD ID
05500
00682
Ensembl ID
ENSG00000131467
ENSG00000044574
Uniprot IDs
B3KQ25
P61289
V9HWJ8
P11021
V9HWB4
PDB IDs
7YQC
7YQD
3IUC
3LDL
3LDN
3LDO
3LDP
5E84
5E85
5E86
5EVZ
5EX5
5EXW
5EY4
5F0X
5F1X
5F2R
6ASY
6CZ1
6DFM
6DFO
6DO2
6DWS
6ZMD
7N1R
Enriched GO Terms of Interacting Partners
?
Regulation Of Translation At Presynapse, Modulating Synaptic Transmission
Cellular Response To Staurosporine
Response To Nutrient Levels
Protein Binding
Protein Domain Specific Binding
Nucleus
Positive Regulation Of Long-term Neuronal Synaptic Plasticity
Cellular Response To Nutrient Levels
Macromolecule Catabolic Process
Cytosol
Positive Regulation Of Protein Metabolic Process
Cellular Response To Alkaloid
Post-translational Protein Modification
Response To Xenobiotic Stimulus
Neuron Projection
Response To Alkaloid
Positive Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Leukocyte Apoptotic Process
Response To UV
Proteolysis
Regulation Of Protein Metabolic Process
Signal Transduction By P53 Class Mediator
Mononuclear Cell Differentiation
Protein-containing Complex
Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Translation Regulator Activity
Cellular Response To Glucose Starvation
Cellular Response To Actinomycin D
Positive Regulation Of Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Cytoplasm
Developmental Process
Modification-dependent Protein Catabolic Process
PML Body
Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator
Regulation Of RNA Metabolic Process
Protein Destabilization
Response To Actinomycin D
HLH Domain Binding
Regulation Of Blood Vessel Endothelial Cell Migration
Regulation Of Protein Stability
Leukocyte Differentiation
Protein Catabolic Process
Regulation Of Long-term Neuronal Synaptic Plasticity
Regulation Of MiRNA-mediated Gene Silencing
Disordered Domain Specific Binding
Glial Cell Apoptotic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Macromolecule Catabolic Process
Regulation Of Protein Localization
Endoplasmic Reticulum
Protein Metabolic Process
Regulation Of Establishment Of Protein Localization
Positive Regulation Of Catabolic Process
Catabolic Process
Protein-folding Chaperone Binding
Protein Catabolic Process
Negative Regulation Of Macromolecule Metabolic Process
Positive Regulation Of Metabolic Process
Modification-dependent Protein Catabolic Process
Regulation Of Protein Catabolic Process
Proteolysis Involved In Protein Catabolic Process
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Autophagy
Negative Regulation Of Establishment Of Protein Localization
Adenyl-nucleotide Exchange Factor Activity
Cotranslational Protein Targeting To Membrane
Molecular Sequestering Activity
Proteolysis
Protein Modification Process
Negative Regulation Of Signaling
Regulation Of Protein Metabolic Process
Negative Regulation Of Metabolic Process
Melatonin Receptor Activity
Regulation Of Metabolic Process
Negative Regulation Of Transport
Response To Stress
Regulation Of Protein Transport
Regulation Of Apoptotic Process
Cellular Response To Stress
Regulation Of Signal Transduction
Signal Transduction
Immunoglobulin Binding
Cupric Ion Binding
Negative Regulation Of Protein Transport
Regulation Of Programmed Cell Death
Negative Regulation Of Cell Communication
Regulation Of Signaling
Negative Regulation Of Leukocyte Activation
Scaffold Protein Binding
Regulation Of Type I Interferon Production
Regulation Of Proteolysis
Protein Folding
Positive Regulation Of Transcription By RNA Polymerase I
Negative Regulation Of T Cell Proliferation
Positive Regulation Of Cholesterol Storage
Negative Regulation Of T Cell Activation
Ubiquitin-like Protein Conjugating Enzyme Binding
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Tagcloud (Intersection)
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