PSME3 and PRR13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		PSME3	PRR13
Description		proteasome activator subunit 3	proline rich 13
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytoplasm Cytosol Cilium Proteasome Activator Complex Membrane Ciliary Basal Body	Nucleus Nucleoplasm Cytosol
	Molecular Function	P53 Binding Protein Binding Identical Protein Binding Endopeptidase Activator Activity MDM2/MDM4 Family Protein Binding	Protein Binding
	Biological Process	Apoptotic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Proteasome assembly
Drugs
Diseases
GWAS			Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252)
Interacting Genes		63 interacting genes: ABCF3 ADAP1 AICDA ATN1 ATP5F1B BBS2 CASP3 CASP6 CASP7 CDC25B CDC42 CEBPA CHEK2 COIL CREBBP DEPTOR DIP2A DMRT3 DTNBP1 DVL3 EAF1 EAF2 FAM90A1 FBXL12 FMR1 FOXD4L1 FXR1 FXR2 GPATCH2L HSPA5 INPP5J ITPKB KANSL1 KBTBD7 KLF2 LNX1 MDM2 MEOX2 NCOA3 NTAQ1 NUDT18 PFDN5 PICK1 PRKAB2 PRR13 RDX RNF111 RPH3AL RPS27 SERF2 SIRT1 SMURF1 SPG7 TBXA2R THAP10 TNFAIP8L1 TP53 TXN2 UBE2H UBE2I WDR25 YWHAQ ZCCHC10	53 interacting genes: AP2M1 BAIAP2 CBLL2 CELF5 DAZAP2 DVL3 EWSR1 FAM133A FUBP1 FXR1 GPAA1 H2BC15 IL16 KHDC4 KLHL12 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP13-1 KRTAP15-1 KRTAP19-5 KRTAP19-7 KRTAP21-2 KRTAP4-12 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP7-1 KRTAP8-1 LGALS3 LNX1 MSX2 NKX1-2 OTX1 PEX5 PLSCR1 PPIA PSMA3 PSME3 RBM47 RP9P RTN4 SDCBP SDCBP2 SMUG1 SREK1IP1 SRI TIAL1 TNFAIP8 TRIP13 VAC14 YPEL3 ZCCHC10
Entrez ID		10197	54458
HPRD ID		05500	13211
Ensembl ID		ENSG00000131467	ENSG00000205352
Uniprot IDs		B3KQ25 P61289 V9HWJ8	Q9NZ81
PDB IDs		7YQC 7YQD
Enriched GO Terms of Interacting Partners?		Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Cellular Response To Staurosporine Response To Nutrient Levels Protein Binding Protein Domain Specific Binding Nucleus Positive Regulation Of Long-term Neuronal Synaptic Plasticity Cellular Response To Nutrient Levels Macromolecule Catabolic Process Cytosol Positive Regulation Of Protein Metabolic Process Cellular Response To Alkaloid Post-translational Protein Modification Response To Xenobiotic Stimulus Neuron Projection Response To Alkaloid Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Leukocyte Apoptotic Process Response To UV Proteolysis Regulation Of Protein Metabolic Process Signal Transduction By P53 Class Mediator Mononuclear Cell Differentiation Protein-containing Complex Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Translation Regulator Activity Cellular Response To Glucose Starvation Cellular Response To Actinomycin D Positive Regulation Of Catabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Cytoplasm Developmental Process Modification-dependent Protein Catabolic Process PML Body Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of RNA Metabolic Process Protein Destabilization Response To Actinomycin D HLH Domain Binding Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Protein Stability Leukocyte Differentiation Protein Catabolic Process Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of MiRNA-mediated Gene Silencing Disordered Domain Specific Binding Glial Cell Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process	Intermediate Filament Cytosol Keratin Filament Identical Protein Binding
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