AIRIM and KRT76

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		AIRIM	KRT76
Description		AFG2 interacting ribosome maturation factor	keratin 76
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol	Nucleus Cytosol Intermediate Filament Keratin Filament Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Ribosome Biogenesis Ribosomal Large Subunit Biogenesis	Cytoskeleton Organization Epidermis Development Keratinization Pigmentation Intermediate Filament Organization Sebaceous Gland Development
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS
Interacting Genes		144 interacting genes: ABI2 ADD1 ANTKMT ATP23 AVPI1 BORCS6 C1orf94 C1QTNF2 CBY2 CCDC120 CCDC125 CCDC33 CCDC88B CCHCR1 CDCA4 CEP55 CINP CRX CSNK2A1 CT55 CTAG1A CTAG1B DISC1 ECM1 ECSIT FAM217B FAM86C1P FTO GET4 GIGYF1 GOLGA2 GOLGA6A GOLGA6L9 HESX1 HOOK2 HOXC8 IHO1 IKZF1 IKZF3 INKA1 KATNAL1 KIAA0753 KIFC3 KLF15 KRT13 KRT16 KRT18 KRT19 KRT24 KRT31 KRT35 KRT40 KRT75 KRT76 KRT80 KRTAP13-3 LDOC1 LMO2 LZTS2 MBD3L1 MDM4 MEI4 MEOX1 MEOX2 MIPOL1 MKRN2 MTFR1L MTUS2 NDUFB7 NECAB2 NFKBID NME4 NUP54 NUTM2F OOEP PAX5 PAX6 PAX7 PBX4 PDE4DIP PHC2 PLK4 PNMA1 POMC POU6F2 PPP1R12C PRDM6 PRMT5 PSMB4 PUDP REL RINT1 RNF20 RNF41 RPH3AL RUSC1 SAPCD2 SDCBP SERTAD1 SERTAD2 SLAIN1 SMARCD1 SOCS6 SORBS3 SPAG5 SPMIP6 STMN3 STN1 STX11 TADA2A TASOR2 TCF12 TCF4 TEKT4 TEPSIN TFIP11 TLE5 TNNI2 TRAF1 TRIM27 TRIM42 TRIM54 TSGA10IP TTC12 TTC23 TTC23L UHMK1 USH1G USHBP1 VBP1 VGLL1 VPS52 YPEL3 ZBED1 ZBTB42 ZMAT1 ZMAT5 ZMYND12 ZNF17 ZNF20 ZNF398 ZNF420 ZNF688 ZSCAN9	47 interacting genes: AIRIM C1orf216 CAMK2A CCDC57 CDC37 CFAP206 DPPA3 EXOC8 FOXR2 FRS3 HGS IPO11 IQUB KIFC3 KRT13 KRT15 KRT16 KRT19 KRT25 KRT26 KRT27 KRT28 KRT31 KRT32 KRT33B KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT75 KRT86 LCA5L LMO4 MID2 MTUS2 NFKBID POLR1C RSPH14 TNS2 TRIM23 TRIM27 TRIM54 TSGA10 WASHC1 ZNF655
Entrez ID		54955	51350
HPRD ID		07918	17123
Ensembl ID		ENSG00000116922	ENSG00000185069
Uniprot IDs		B4DRQ5 B7Z9X8 Q9NX04	Q01546
PDB IDs		8RHN
Enriched GO Terms of Interacting Partners?		Cytoskeleton Organization Protein Binding Structural Constituent Of Skin Epidermis Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Organization Cytoskeleton Supramolecular Fiber Organization Intermediate Filament Microtubule-based Process Organelle Organization Microtubule Cytoskeleton Organization Cytoplasmic Microtubule Organization Identical Protein Binding Regulation Of Transcription By RNA Polymerase II Structural Molecule Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Centrosome Nucleus Regulation Of Nucleobase-containing Compound Metabolic Process HMG Box Domain Binding Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity Transcription Coactivator Activity DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Primary Metabolic Process Microtubule Somite Specification	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Supramolecular Fiber Organization Morphogenesis Of An Epithelium Cytoskeleton Epithelial Cell Differentiation Tissue Morphogenesis Cytoskeleton Organization Organelle Organization Extracellular Exosome Anatomical Structure Morphogenesis Cell Differentiation Radial Spoke Hair Cycle Protein Binding Cellular Developmental Process Cytosol Hair Follicle Morphogenesis Phosphatidylinositol 3-kinase Inhibitor Activity Structural Constituent Of Cytoskeleton Regulation Of Autophagy Developmental Process Epidermis Development Negative Regulation Of Viral Transcription Exocyst Keratinization Suppression Of Viral Release By Host Arp2/3 Complex-mediated Actin Nucleation Hair Cycle Process Positive Regulation Of Autophagy Regulation Of Viral Transcription Actin Nucleation
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