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ARPC5 and NR3C1
Number of citations of the paper that reports this interaction (PMID
10508170
)
70
Data Source:
BioGRID
(two hybrid)
ARPC5
NR3C1
Gene Name
actin related protein 2/3 complex, subunit 5, 16kDa
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Arp2/3 Protein Complex
Focal Adhesion
Actin Cytoskeleton
Cell Projection
Extracellular Vesicular Exosome
Nucleus
Nucleoplasm
Cytoplasm
Mitochondrial Matrix
Cytosol
Membrane
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
Actin Filament Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding
RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription
Sequence-specific DNA Binding Transcription Factor Activity
Glucocorticoid Receptor Activity
Steroid Binding
Protein Binding
Zinc Ion Binding
Glucocorticoid-activated RNA Polymerase II Transcription Factor Binding Transcription Factor Activity
Protein Dimerization Activity
Steroid Hormone Binding
Biological Process
Movement Of Cell Or Subcellular Component
Axon Guidance
Actin Cytoskeleton Organization
Arp2/3 Complex-mediated Actin Nucleation
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Innate Immune Response
Ephrin Receptor Signaling Pathway
Regulation Of Gluconeogenesis
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
Transcription Initiation From RNA Polymerase II Promoter
Signal Transduction
Glucocorticoid Metabolic Process
Gene Expression
Chromatin Modification
Adrenal Gland Development
Regulation Of Glucocorticoid Biosynthetic Process
Maternal Behavior
Glucocorticoid Receptor Signaling Pathway
Glucocorticoid Mediated Signaling Pathway
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Mammary Gland Duct Morphogenesis
Cellular Response To Steroid Hormone Stimulus
Negative Regulation Of Glucocorticoid Mediated Signaling Pathway
Pathways
EPHB-mediated forward signaling
Axon guidance
EPH-Ephrin signaling
Fcgamma receptor (FCGR) dependent phagocytosis
Regulation of actin dynamics for phagocytic cup formation
Innate Immune System
BMAL1:CLOCK,NPAS2 activates circadian gene expression
Drugs
Flunisolide
Diflorasone
Alclometasone
Medrysone
Amcinonide
Fluorometholone
Megestrol
Beclometasone dipropionate
Betamethasone
Desoximetasone
Fluticasone Propionate
Fluocinolone Acetonide
Halobetasol Propionate
Triamcinolone
Prednisone
Flumethasone Pivalate
Fludrocortisone
Hydrocortisone
Mometasone
Hydrocortamate
Mifepristone
Clocortolone
Flurandrenolide
Prednisolone
Loteprednol
Rimexolone
Methylprednisolone
Clobetasol
Fluocinonide
Prednicarbate
Fluoxymesterone
Budesonide
Dexamethasone
Desonide
Cortisone acetate
Paramethasone
Ciclesonide
Hexane-1,6-Diol
Difluprednate
Fluticasone furoate
Diseases
GWAS
Protein-Protein Interactions
6 interactors:
ACTR2
ACTR3
ARPC1B
ARPC4
MAPKAPK2
NR3C1
135 interactors:
ADA
AR
ARPC5
BAG1
CALM1
CALR
CEBPA
CEBPB
CENPB
CHD9
COPS6
CREB1
CREBBP
DAP3
DAXX
DCAF6
DDX54
ECD
ETS1
ETS2
FKBP4
FTH1
FYN
GNB1
GNB2
GNB2L1
GRIP1
HDAC6
HMGB1
HMGB2
HMOX2
HNRNPA1
HNRNPU
HSP90AA1
HSPA1A
HSPD1
IDE
IFNGR2
JUN
KAT5
KDM5A
KPNA2
LCK
LRIF1
MAFF
MAPK1
MAPK15
MAPK8
MDM2
MED1
MED14
MED25
MSX2
NCL
NCOA1
NCOA2
NCOA3
NCOA4
NCOA6
NCOR1
NCOR2
NEDD4L
NFKB1
NFKB2
NR0B1
NR1H3
NR2E3
NR2F2
NR2F6
NR3C2
NR4A1
NRIP1
ONECUT1
OSGEP
PBX1
PELP1
PIAS2
PML
POLR1D
POU1F1
POU2F1
POU2F2
PPARGC1A
PRKACA
PRKDC
PRPF6
PSMC3IP
PTGES3
PTMS
RAD54L2
RAD9A
RAF1
RAN
RARA
RBM14
RELA
RNF14
RXRB
SFN
SLC25A4
SMAD3
SMARCA2
SMARCA4
SMARCB1
SMARCC1
SMARCD1
SMARCE1
SRA1
SRC
STAT3
STAT5A
STAT5B
SUMO1
SUMO4
SVIL
SYT1
TADA2A
TBP
TDG
TGFB1I1
TMF1
TP53
TRIM24
TRIM28
TSG101
TXN
UBB
UBE2I
UBE2L3
YWHAH
ZBTB16
ZBTB20
ZBTB3
ZBTB9
ZNF496
Entrez ID
10092
2908
HPRD ID
11969
00679
Ensembl ID
ENSG00000162704
ENSG00000113580
Uniprot IDs
O15511
B7Z7I2
E5KQF5
E5KQF6
F1D8N4
P04150
PDB IDs
1M2Z
1NHZ
1P93
3BQD
3CLD
3E7C
3H52
3K22
3K23
4HN5
4HN6
Enriched GO Terms of Interacting Partners
?
Arp2/3 Complex-mediated Actin Nucleation
Actin Nucleation
Positive Regulation Of Actin Filament Polymerization
Positive Regulation Of Protein Polymerization
Positive Regulation Of Protein Complex Assembly
Regulation Of Actin Filament Polymerization
Positive Regulation Of Cytoskeleton Organization
Regulation Of Actin Polymerization Or Depolymerization
Regulation Of Actin Filament Length
Meiotic Chromosome Movement Towards Spindle Pole
Actin Filament Organization
Positive Regulation Of Cellular Component Biogenesis
Regulation Of Cellular Component Size
Regulation Of Protein Complex Assembly
Asymmetric Cell Division
Regulation Of Actin Cytoskeleton Organization
Positive Regulation Of Organelle Organization
Regulation Of Actin Filament-based Process
Meiotic Cytokinesis
Ephrin Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Regulation Of Cytoskeleton Organization
Actin Cytoskeleton Organization
Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis
Fc-gamma Receptor Signaling Pathway
Fc Receptor Mediated Stimulatory Signaling Pathway
Actin Filament-based Process
Positive Regulation Of Immune Response
Endocytosis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Innate Immune Response
Regulation Of Immune Response
Phagocytosis
Fc Receptor Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Immune System Process
Regulation Of Organelle Organization
Immune Response-activating Cell Surface Receptor Signaling Pathway
Establishment Of Chromosome Localization
Cytoskeleton Organization
Spindle Localization
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Axon Guidance
Immune Response
Regulation Of Immune System Process
Defense Response
Meiotic Chromosome Segregation
Vesicle-mediated Transport
Axonogenesis
Movement Of Cell Or Subcellular Component
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Gene Expression
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of RNA Metabolic Process
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Transcription From RNA Polymerase II Promoter
RNA Biosynthetic Process
Intracellular Receptor Signaling Pathway
Gene Expression
RNA Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter
Nucleobase-containing Compound Metabolic Process
Positive Regulation Of Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Regulation Of Metabolic Process
Nitrogen Compound Metabolic Process
Cellular Macromolecule Biosynthetic Process
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of Gene Expression
Negative Regulation Of RNA Biosynthetic Process
Macromolecule Biosynthetic Process
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Biosynthetic Process
Intracellular Steroid Hormone Receptor Signaling Pathway
Response To Hormone
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Response To Organic Substance
Cellular Metabolic Process
Cellular Response To Hormone Stimulus
Biosynthetic Process
Regulation Of Cellular Process
Cellular Response To Organic Substance
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Androgen Receptor Signaling Pathway
Response To Steroid Hormone
Response To Organic Cyclic Compound
Transcription Initiation From RNA Polymerase II Promoter
Response To Lipid
DNA-templated Transcription, Initiation
Cell Differentiation
Tagcloud
?
2xglucocorticoid
2xgre
agonism
agonists
beas
bronchial
budesonide
cdkn1c
ciclesonide
combat
dexamethasone
dusp1
fluticasone
formoterol
furoate
glucocorticoid
glucocorticoids
gre
gsk9027
gw870086x
ikk2
phosphoinositide
propionate
reporter
rgs2
ru24858
suboptimal
tsc22d3
viii
Tagcloud (Difference)
?
2xglucocorticoid
2xgre
agonism
agonists
beas
bronchial
budesonide
cdkn1c
ciclesonide
combat
dexamethasone
dusp1
fluticasone
formoterol
furoate
glucocorticoid
glucocorticoids
gre
gsk9027
gw870086x
ikk2
phosphoinositide
propionate
reporter
rgs2
ru24858
suboptimal
tsc22d3
viii
Tagcloud (Intersection)
?