KRTAP10-7 and SLC23A1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-7	SLC23A1
Gene Name		keratin associated protein 10-7	solute carrier family 23 (ascorbic acid transporter), member 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Cytoplasm Plasma Membrane Integral Component Of Plasma Membrane Brush Border Basal Plasma Membrane Membrane Apical Plasma Membrane Intracellular Organelle Extracellular Vesicular Exosome
	Molecular Function		Protein Binding L-ascorbate:sodium Symporter Activity Sodium Ion Transmembrane Transporter Activity Nucleobase Transmembrane Transporter Activity L-ascorbic Acid Transporter Activity Dehydroascorbic Acid Transporter Activity Sodium-dependent L-ascorbate Transmembrane Transporter Activity
	Biological Process		Nucleobase-containing Compound Metabolic Process Vitamin Metabolic Process Water-soluble Vitamin Metabolic Process Sodium Ion Transport Brain Development Response To Toxic Substance Nucleobase Transport L-ascorbic Acid Transport L-ascorbic Acid Metabolic Process Lung Development Vitamin Transmembrane Transport Sodium Ion Transmembrane Transport Small Molecule Metabolic Process Dehydroascorbic Acid Transport Transepithelial L-ascorbic Acid Transport
Pathways			Metabolism of vitamins and cofactors Defective CD320 causes methylmalonic aciduria Defective GIF causes intrinsic factor deficiency Defective LMBRD1 causes methylmalonic aciduria and homocystinuria type cblF Defective HLCS causes multiple carboxylase deficiency Defective MMAB causes methylmalonic aciduria type cblB Defective BTD causes biotidinase deficiency Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC Defective MTR causes methylmalonic aciduria and homocystinuria type cblG Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD Vitamin C (ascorbate) metabolism Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE Defective MMAA causes methylmalonic aciduria type cblA Defective CUBN causes hereditary megaloblastic anemia 1 Defective AMN causes hereditary megaloblastic anemia 1 Defective MUT causes methylmalonic aciduria mut type Metabolism of water-soluble vitamins and cofactors Defects in biotin (Btn) metabolism Defective TCN2 causes hereditary megaloblastic anemia Defects in cobalamin (B12) metabolism Defects in vitamin and cofactor metabolism
Drugs			Vitamin C
Diseases
GWAS
Protein-Protein Interactions		215 interactors: AEN AES ALDH3B1 ANKRD36BP1 AP1M1 APP AQP1 AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BUD31 BYSL C16orf59 C19orf57 C19orf66 C8orf33 C9orf9 CARHSP1 CARKD CATIP CBX2 CCDC185 CCDC26 CCNG1 CDCA7L CHIC2 CHRD CHRNG CLK1 CLK4 COL8A1 CRCT1 CREB5 CSNK1G1 CSNK1G2 CTNNBIP1 CTRC CXCL16 DAAM2 DERL2 DHX57 DMRT3 E2F6 E4F1 EHHADH FAM124B FAM161A FAM27E3 FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GEM GLIDR GLP1R GNE GOLGA8EP GRN GSTP1 GUCD1 HBZ HHEX HPCAL1 HSBP1 HSD3B7 IGSF8 ING5 INPP5D IQUB KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2A LCE3E LCE4A LIMS2 LINC00242 LMNA LMO2 LRCH4 MAPKBP1 MCM5 MOBP MRGBP MXD3 MXI1 NAA10 NOL12 NOTCH2NL NPBWR2 NPDC1 NUBP2 NUDCD3 NUFIP2 P2RY6 PCED1A PCSK5 PDIA5 PDLIM5 PFKL PIN1 POLL POM121L8P PPARD PRKAB2 PRM2 PRR13 PTGDS PTGER3 PTPMT1 PVR PVRL2 PVRL3 RNF175 RPF1 RPL11 RPL36AL RPS28 RPUSD3 RSPO2 RTN4RL1 RWDD2B SCNM1 SDCBP SLC23A1 SLC25A48 SLC6A20 SMCO4 SMCP SPATA3 SPATA8 SPG7 SPRY1 SSX2IP STK16 SUV39H1 TAPBPL TCEA2 TCEANC THAP1 THAP6 TMA16 TMEM8A TNP2 TNS2 TOR1A TREX1 TRIM42 TULP3 TXNDC5 TYRO3 UCP2 UXT VTI1B WDYHV1 WNT11 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF101 ZNF124 ZNF133 ZNF155 ZNF165 ZNF169 ZNF175 ZNF180 ZNF2 ZNF20 ZNF223 ZNF250 ZNF26 ZNF266 ZNF32 ZNF320 ZNF329 ZNF337 ZNF41 ZNF417 ZNF418 ZNF419 ZNF425 ZNF433 ZNF439 ZNF490 ZNF543 ZNF555 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF670 ZNF697 ZNF707 ZNF778 ZNF792 ZNF846 ZNHIT1 ZSCAN26	12 interactors: ADAMTSL4 AHCYL1 KRT31 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP4-2 MTUS2 NOTCH2NL
Entrez ID		386675	9963
HPRD ID		11193	04810
Ensembl ID		ENSG00000205441	ENSG00000170482
Uniprot IDs		P60409	Q9UHI7
PDB IDs
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Cellular Metabolic Process Cellular Process Regulation Of Metabolic Process Regulation Of Cellular Process Susceptibility To T Cell Mediated Cytotoxicity Transepithelial Transport Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Keratinization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Gene Expression Cellular Response To Oxygen Levels Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Penetration Of Zona Pellucida Negative Regulation Of Transcription From RNA Polymerase II Promoter Spinal Cord Dorsal/ventral Patterning Positive Regulation Of Immune Response To Tumor Cell Multicellular Organismal Development Spinal Cord Patterning Negative Regulation Of Cellular Metabolic Process Respiratory Tube Development
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