KRTAP10-7 and PVRL2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KRTAP10-7	PVRL2
Gene Name		keratin associated protein 10-7	poliovirus receptor-related 2 (herpesvirus entry mediator B)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Keratin Filament	Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Cell Surface Integral Component Of Membrane Extracellular Vesicular Exosome
	Molecular Function		Virus Receptor Activity Protein Binding Coreceptor Activity Identical Protein Binding Protein Homodimerization Activity Cell Adhesion Molecule Binding
	Biological Process		Acrosome Assembly Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immunoglobulin Mediated Immune Response Cytoskeleton Organization Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Spermatid Development Spermatid Nucleus Differentiation Fertilization Response To Virus Fusion Of Virus Membrane With Host Plasma Membrane Sperm Mitochondrion Organization Cell Part Morphogenesis Positive Regulation Of Mast Cell Activation Cell Junction Assembly Adherens Junction Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Adhesion Of Symbiont To Host Cilium Organization Cell-cell Junction Organization Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Coreceptor-mediated Virion Attachment To Host Cell Regulation Of Immune Response Establishment Of Mitochondrion Localization Susceptibility To T Cell Mediated Cytotoxicity
Pathways			Nectin/Necl trans heterodimerization Cell junction organization Cell-cell junction organization Adherens junctions interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS			Age-related macular degeneration ( 23326517) Alzheimer's disease ( 18823527 22159054) Alzheimer's disease (age of onset) ( 22005931) Alzheimer's disease (late onset) ( 20885792 23565137) Alzheimer's disease biomarkers ( 23419831) HDL cholesterol ( 21909109) Waist-to-hip circumference ratio (interaction) ( 23192594)
Protein-Protein Interactions		215 interactors: AEN AES ALDH3B1 ANKRD36BP1 AP1M1 APP AQP1 AVPI1 B4GALT7 BAHD1 BCL6B BMP7 BUD31 BYSL C16orf59 C19orf57 C19orf66 C8orf33 C9orf9 CARHSP1 CARKD CATIP CBX2 CCDC185 CCDC26 CCNG1 CDCA7L CHIC2 CHRD CHRNG CLK1 CLK4 COL8A1 CRCT1 CREB5 CSNK1G1 CSNK1G2 CTNNBIP1 CTRC CXCL16 DAAM2 DERL2 DHX57 DMRT3 E2F6 E4F1 EHHADH FAM124B FAM161A FAM27E3 FAM74A4 FAM76B FARS2 GABARAPL1 GABARAPL2 GEM GLIDR GLP1R GNE GOLGA8EP GRN GSTP1 GUCD1 HBZ HHEX HPCAL1 HSBP1 HSD3B7 IGSF8 ING5 INPP5D IQUB KLHL38 KRT20 KRT83 KRTAP10-3 KRTAP10-5 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP4-2 KRTAP5-6 KRTAP5-9 KRTAP9-2 LCE1B LCE2A LCE3E LCE4A LIMS2 LINC00242 LMNA LMO2 LRCH4 MAPKBP1 MCM5 MOBP MRGBP MXD3 MXI1 NAA10 NOL12 NOTCH2NL NPBWR2 NPDC1 NUBP2 NUDCD3 NUFIP2 P2RY6 PCED1A PCSK5 PDIA5 PDLIM5 PFKL PIN1 POLL POM121L8P PPARD PRKAB2 PRM2 PRR13 PTGDS PTGER3 PTPMT1 PVR PVRL2 PVRL3 RNF175 RPF1 RPL11 RPL36AL RPS28 RPUSD3 RSPO2 RTN4RL1 RWDD2B SCNM1 SDCBP SLC23A1 SLC25A48 SLC6A20 SMCO4 SMCP SPATA3 SPATA8 SPG7 SPRY1 SSX2IP STK16 SUV39H1 TAPBPL TCEA2 TCEANC THAP1 THAP6 TMA16 TMEM8A TNP2 TNS2 TOR1A TREX1 TRIM42 TULP3 TXNDC5 TYRO3 UCP2 UXT VTI1B WDYHV1 WNT11 ZBTB24 ZBTB38 ZBTB9 ZFYVE26 ZNF101 ZNF124 ZNF133 ZNF155 ZNF165 ZNF169 ZNF175 ZNF180 ZNF2 ZNF20 ZNF223 ZNF250 ZNF26 ZNF266 ZNF32 ZNF320 ZNF329 ZNF337 ZNF41 ZNF417 ZNF418 ZNF419 ZNF425 ZNF433 ZNF439 ZNF490 ZNF543 ZNF555 ZNF564 ZNF572 ZNF578 ZNF581 ZNF587 ZNF625 ZNF670 ZNF697 ZNF707 ZNF778 ZNF792 ZNF846 ZNHIT1 ZSCAN26	20 interactors: ATP5J2 CD226 DUS2 KRTAP10-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP5-9 LYRM4 MAPK6 MDFI MLLT4 NOTCH2NL PICK1 PVRL3 PVRL4 SIAH1 TIGIT TNFRSF12A USP53
Entrez ID		386675	5819
HPRD ID		11193	02879
Ensembl ID		ENSG00000205441	ENSG00000130202
Uniprot IDs		P60409	Q92692
PDB IDs			3R0N 4DFH 4DFI 4HZA
Enriched GO Terms of Interacting Partners?		RNA Biosynthetic Process Transcription, DNA-templated RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Cellular Metabolic Process Cellular Process Regulation Of Metabolic Process Regulation Of Cellular Process Susceptibility To T Cell Mediated Cytotoxicity Transepithelial Transport Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Metabolic Process Keratinization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Developmental Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Negative Regulation Of Mesenchymal Cell Proliferation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of Gene Expression Cellular Response To Oxygen Levels Cellular Response To Topologically Incorrect Protein Cellular Response To Stress Penetration Of Zona Pellucida Negative Regulation Of Transcription From RNA Polymerase II Promoter Spinal Cord Dorsal/ventral Patterning Positive Regulation Of Immune Response To Tumor Cell Multicellular Organismal Development Spinal Cord Patterning Negative Regulation Of Cellular Metabolic Process Respiratory Tube Development	Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Organization
Tagcloud ?			adarb2 asymptomatic carriers carrying ceacam6 cntnap2 col19a1 commonest consider def4 dopaminergic draxin fcer2 functionally g2019s hbg1 idiopathic initiating lrrk2 merit ncapg2 never parkinson pd seq slc2a14 snca tcl1b variations
Tagcloud (Difference) ?			adarb2 asymptomatic carriers carrying ceacam6 cntnap2 col19a1 commonest consider def4 dopaminergic draxin fcer2 functionally g2019s hbg1 idiopathic initiating lrrk2 merit ncapg2 never parkinson pd seq slc2a14 snca tcl1b variations
Tagcloud (Intersection) ?