CPNE2 and MEI4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CPNE2	MEI4
Description		copine 2	meiotic double-stranded break formation protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Plasma Membrane Membrane Extracellular Exosome	Lateral Element Chromosome
	Molecular Function	Protein Binding Calcium-dependent Phospholipid Binding Metal Ion Binding	Protein Binding
	Biological Process	Cellular Response To Calcium Ion	DNA Recombination Homologous Chromosome Pairing At Meiosis Spermatogenesis Meiotic DNA Double-strand Break Formation Oogenesis Meiotic Cell Cycle
Pathways
Drugs
Diseases
GWAS			Brain volume in infants (white matter) ( 28763065) Cadmium levels ( 26025379) Daytime nap ( 33568662) HDL cholesterol levels in HIV infection ( 33109212) Macular thickness ( 30535121)
Interacting Genes		28 interacting genes: ACTB ANXA7 BCOR CDKN1A CT55 EFHC2 GBP7 IKBKG KATNBL1 LNX1 MEI4 MEOX2 MYCBP NCKIPSD PDCD6 PICK1 PPP5C RDX REL SKIL SORBS3 TCF4 TERF2IP THAP4 TRIM27 UBA3 UBE2M UBE2O	36 interacting genes: AFMID AIRIM BAG4 C19orf25 CABP5 CDKN2D CHAF1A CPNE2 CST9L CTTNBP2 DNTT EIF5A FKBP6 GRB2 HSD3B7 IQGAP1 LGALS14 MACO1 METTL21A MLX MTMR9 MYO5B NGB NME7 OSGIN1 PAFAH1B3 PHYHIPL PLEKHA4 POLR1C R3HDM2 TRAPPC2L TRIM59 TSEN15 TSSK3 USHBP1 VPS26C
Entrez ID		221184	101928601
HPRD ID		05015
Ensembl ID		ENSG00000140848	ENSG00000269964
Uniprot IDs		Q96FN4	A8MW99
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytoplasm Nucleus Identical Protein Binding Negative Regulation Of Type I Interferon Production Ubiquitin-protein Transferase Activity NEDD8 Transferase Activity Nucleoplasm Regulation Of Canonical NF-kappaB Signal Transduction Regulation Of Cellular Component Organization Apical Protein Localization Arp2/3 Complex Binding Positive Regulation Of Canonical NF-kappaB Signal Transduction Protein Domain Specific Binding Protein Neddylation
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