NIN and C14orf166

Number of citations of the paper that reports this interaction (PMID 15147888)
6

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		NIN	C14orf166
Gene Name		ninein (GSK3B interacting protein)	chromosome 14 open reading frame 166
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleolus Centrosome Centriole Microtubule	Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center Cytosol Perinuclear Region Of Cytoplasm TRNA-splicing Ligase Complex
	Molecular Function	Calcium Ion Binding Protein Binding GTP Binding	RNA Polymerase II Core Binding RNA Binding Protein Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Microtubule Anchoring At Centrosome Centrosome Localization Centrosome-templated Microtubule Nucleation	Transcription, DNA-templated TRNA Splicing, Via Endonucleolytic Cleavage And Ligation Viral Process Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Transport
Pathways
Drugs
Diseases
GWAS		Cognitive performance ( 20125193)
Protein-Protein Interactions		9 interactors: ABI1 AURKA BICD1 C14orf166 GSK3B PIAS1 PRKACA SUMO1 UBE2I	4 interactors: DISC1 FAM98A GLP1R NIN
Entrez ID		51199	51637
HPRD ID		09785	16615
Ensembl ID		ENSG00000100503	ENSG00000087302
Uniprot IDs		Q5XUU0 Q8N4C6	Q549M8 Q9Y224
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Proteasomal Protein Catabolic Process Peptidyl-amino Acid Modification Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Protein Sumoylation Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Binding Regulation Of Proteolysis Positive Regulation Of Proteolysis Innate Immune Response Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Binding Peptidyl-serine Phosphorylation Positive Regulation Of Protein Export From Nucleus Protein Localization To Cytoskeleton Regulation Of Protein Binding Regulation Of Cellular Protein Metabolic Process Protein Localization To Organelle Cellular Protein Modification Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Interferon-gamma-mediated Signaling Pathway Regulation Of Response To Interferon-gamma Regulation Of Metabolic Process Regulation Of Protein Metabolic Process Immune Response Regulation Of Immune System Process Regulation Of Cardiac Muscle Hypertrophy Regulation Of Protein Export From Nucleus Defense Response Negative Regulation Of Biosynthetic Process Response To Cytokine Histone Phosphorylation Peptidyl-lysine Modification Regulation Of Signal Transduction Cellular Protein Metabolic Process Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cell Differentiation Regulation Of Immune Response Negative Regulation Of Protein Binding Positive Regulation Of Protein Modification Process Nuclear Envelope Organization Regulation Of Signaling Organelle Organization	Centrosome-templated Microtubule Nucleation Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Microtubule Anchoring At Centrosome Microtubule Anchoring At Microtubule Organizing Center Cellular Metal Ion Homeostasis Microtubule Cytoskeleton Organization Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Ion Homeostasis Mitochondrial Calcium Ion Homeostasis Regulation Of Synapse Maturation Microtubule Nucleation Cellular Homeostasis TOR Signaling CAMP-mediated Signaling Microtubule-based Process Microtubule Polymerization Positive Regulation Of Neuroblast Proliferation Activation Of Adenylate Cyclase Activity Cyclic-nucleotide-mediated Signaling Chemical Homeostasis Centrosome Localization Positive Regulation Of Adenylate Cyclase Activity Cellular Response To Glucagon Stimulus Microtubule Polymerization Or Depolymerization Positive Regulation Of Lyase Activity Cell Proliferation In Forebrain Microtubule Anchoring Cytoskeleton Organization Response To Glucagon Regulation Of Neuroblast Proliferation Positive Regulation Of Neural Precursor Cell Proliferation Regulation Of Adenylate Cyclase Activity Positive Regulation Of CAMP Biosynthetic Process Cerebral Cortex Radially Oriented Cell Migration Regulation Of Cyclase Activity Positive Regulation Of CAMP Metabolic Process Positive Regulation Of Stem Cell Proliferation Cellular Protein Localization Homeostatic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Cyclic Nucleotide Metabolic Process Regulation Of CAMP Biosynthetic Process Regulation Of Synapse Organization Cerebral Cortex Cell Migration Regulation Of Synapse Structure Or Activity Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Tagcloud ?		3op amido arbuzov arhnp arnc carbamoyl carboxylation cnar dinickel dismantling ipr ipr2 isonitrile methacrylamide narh nhar nix ococh opr2 osime3 phosphinate pincer poc poch2 reactivities siloxide siloxido trinickel valent	arch archaea archease asw c22orf28 c2orf49 cgi cooperation d10wsu52e ddx1 dead eukaryotes faap fam98b guanylate helicase hspc117 implies interplay ligase ligases ligation multimeric orthologous rtcb splicing trna trnas zbtb8os
Tagcloud (Difference) ?		3op amido arbuzov arhnp arnc carbamoyl carboxylation cnar dinickel dismantling ipr ipr2 isonitrile methacrylamide narh nhar nix ococh opr2 osime3 phosphinate pincer poc poch2 reactivities siloxide siloxido trinickel valent	arch archaea archease asw c22orf28 c2orf49 cgi cooperation d10wsu52e ddx1 dead eukaryotes faap fam98b guanylate helicase hspc117 implies interplay ligase ligases ligation multimeric orthologous rtcb splicing trna trnas zbtb8os
Tagcloud (Intersection) ?