Diabetes - New-wiki

Novel	Symbols	Name 1	Name 2	Pathways 1 Hide	Pathways 2 Hide	Drugs 1 Hide	Drugs 2 Hide	Diseases 1 Hide	Diseases 2 Hide
Novel Novel	Symbols RSRC1 and LEKR1	Name 1 arginine and serine rich coiled-coil 1	Name2 leucine, glutamate and lysine rich 1	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols FLT3 and FMO1	Name 1 fms related receptor tyrosine kinase 3	Name2 flavin containing dimethylaniline monoxygenase 1	Pathway 1 PI3K Cascade PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling FLT3 Signaling FLT3 Signaling STAT5 Activation FLT3 mutants bind TKIs STAT5 activation downstream of FLT3 ITD mutants KW2449-resistant FLT3 mutants semaxanib-resistant FLT3 mutants crenolanib-resistant FLT3 mutants gilteritinib-resistant FLT3 mutants lestaurtinib-resistant FLT3 mutants midostaurin-resistant FLT3 mutants pexidartinib-resistant FLT3 mutants ponatinib-resistant FLT3 mutants quizartinib-resistant FLT3 mutants sorafenib-resistant FLT3 mutants sunitinib-resistant FLT3 mutants tandutinib-resistant FLT3 mutants linifanib-resistant FLT3 mutants tamatinib-resistant FLT3 mutants Signaling by FLT3 ITD and TKD mutants Signaling by FLT3 ITD and TKD mutants Negative regulation of FLT3 FLT3 signaling through SRC family kinases FLT3 signaling through SRC family kinases FLT3 signaling by CBL mutants	Pathway 2 Degradation of cysteine and homocysteine FMO oxidises nucleophiles	Drugs 1 Sorafenib Sunitinib XL999 Tandutinib Linifanib Lestaurtinib Midostaurin Ponatinib Nintedanib Pacritinib Tivozanib Fostamatinib Gilteritinib Brigatinib Fedratinib Amuvatinib Quizartinib Pexidartinib Pralsetinib	Drugs 2	Diseases 1 Acute myeloid leukemia (AML)	Diseases 2
Novel Novel	Symbols TRIM31 and BTNL2	Name 1 tripartite motif containing 31	Name2 butyrophilin like 2	Pathway 1 Interferon gamma signaling	Pathway 2 Butyrophilin (BTN) family interactions	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols IFT172 and DNAJC27	Name 1 intraflagellar transport 172	Name2 DnaJ heat shock protein family (Hsp40) member C27	Pathway 1 Hedgehog 'off' state Intraflagellar transport Intraflagellar transport	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols CIT and ABCB9	Name 1 citron rho-interacting serine/threonine kinase	Name2 ATP binding cassette subfamily B member 9	Pathway 1 RHO GTPases activate CIT RHO GTPases activate CIT RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RAC1 GTPase cycle	Pathway 2 ABC-family proteins mediated transport	Drugs 1 Fostamatinib	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols BDNF and MPPED2	Name 1 brain derived neurotrophic factor	Name2 metallophosphoesterase domain containing 2	Pathway 1 PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling MECP2 regulates transcription of neuronal ligands BDNF activates NTRK2 (TRKB) signaling Activated NTRK2 signals through RAS Activated NTRK2 signals through PLCG1 Activated NTRK2 signals through PLCG1 Activated NTRK2 signals through PI3K Activated NTRK2 signals through FRS2 and FRS3 Activated NTRK2 signals through FRS2 and FRS3 Activated NTRK2 signals through FYN NTRK2 activates RAC1 NTRK2 activates RAC1 Activated NTRK2 signals through CDK5 NPAS4 regulates expression of target genes	Pathway 2	Drugs 1 CX-717 Copper Chondroitin sulfate Esketamine	Drugs 2	Diseases 1 Congenital central hypoventilation syndrome (CCHS)	Diseases 2
Novel Novel	Symbols RAB10 and EFR3B	Name 1 RAB10, member RAS oncogene family	Name2 EFR3 homolog B	Pathway 1 Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols BBS1 and PEPD	Name 1 Bardet-Biedl syndrome 1	Name2 peptidase D	Pathway 1 BBSome-mediated cargo-targeting to cilium	Pathway 2	Drugs 1	Drugs 2	Diseases 1 Bardet-Biedl syndrome (BBS)	Diseases 2
Novel Novel	Symbols POFUT2 and CLDN14	Name 1 protein O-fucosyltransferase 2	Name2 claudin 14	Pathway 1 O-glycosylation of TSR domain-containing proteins	Pathway 2 Tight junction interactions	Drugs 1	Drugs 2	Diseases 1	Diseases 2 Deafness, autosomal recessive
Novel Novel	Symbols TRIM38 and TSBP1	Name 1 tripartite motif containing 38	Name2 testis expressed basic protein 1	Pathway 1 Interferon gamma signaling	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols AGPS and KCNH7	Name 1 alkylglycerone phosphate synthase	Name2 potassium voltage-gated channel subfamily H member 7	Pathway 1 Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Pathway 2 Voltage gated Potassium channels	Drugs 1	Drugs 2 Enflurane Ibutilide Amitriptyline Doxazosin Promethazine Miconazole Amiodarone Terazosin Vanoxerine Silodosin	Diseases 1 Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)	Diseases 2
Novel Novel	Symbols AFF3 and DPP8	Name 1 ALF transcription elongation factor 3	Name2 dipeptidyl peptidase 8	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols REEP5 and LGR5	Name 1 receptor accessory protein 5	Name2 leucine rich repeat containing G protein-coupled receptor 5	Pathway 1	Pathway 2 Regulation of FZD by ubiquitination	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols TMA16 and FSTL5	Name 1 translation machinery associated 16 homolog	Name2 follistatin like 5	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols NAT1 and CSMD1	Name 1 N-acetyltransferase 1	Name2 CUB and Sushi multiple domains 1	Pathway 1 Acetylation Paracetamol ADME	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols BZW2 and AGMO	Name 1 basic leucine zipper and W2 domains 2	Name2 alkylglycerol monooxygenase	Pathway 1	Pathway 2 Triglyceride biosynthesis	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols AASS and FSCN3	Name 1 aminoadipate-semialdehyde synthase	Name2 fascin actin-bundling protein 3	Pathway 1 Lysine catabolism	Pathway 2	Drugs 1 Glutamic acid NADH NADPH L-Saccharopine	Drugs 2	Diseases 1 Hyperlysinemia	Diseases 2
Novel Novel	Symbols ZDHHC8 and MICAL3	Name 1 zDHHC palmitoyltransferase 8	Name2 microtubule associated monooxygenase, calponin and LIM domain containing 3	Pathway 1 HDL assembly Maturation of spike protein	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols TYW5 and SATB2-AS1	Name 1 tRNA-yW synthesizing protein 5	Name2 SATB2 antisense RNA 1	Pathway 1 Synthesis of wybutosine at G37 of tRNA(Phe)	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel Novel	Symbols COLEC10 and ALG5	Name 1 collectin subfamily member 10	Name2 ALG5 dolichyl-phosphate beta-glucosyltransferase	Pathway 1 Lectin pathway of complement activation Initial triggering of complement	Pathway 2 Synthesis of dolichyl-phosphate-glucose	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols RSRC1 and LEKR1	Name 1 arginine and serine rich coiled-coil 1	Name2 leucine, glutamate and lysine rich 1	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols FLT3 and FMO1	Name 1 fms related receptor tyrosine kinase 3	Name2 flavin containing dimethylaniline monoxygenase 1	Pathway 1 PI3K Cascade PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer RAF/MAP kinase cascade PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling FLT3 Signaling FLT3 Signaling STAT5 Activation FLT3 mutants bind TKIs STAT5 activation downstream of FLT3 ITD mutants KW2449-resistant FLT3 mutants semaxanib-resistant FLT3 mutants crenolanib-resistant FLT3 mutants gilteritinib-resistant FLT3 mutants lestaurtinib-resistant FLT3 mutants midostaurin-resistant FLT3 mutants pexidartinib-resistant FLT3 mutants ponatinib-resistant FLT3 mutants quizartinib-resistant FLT3 mutants sorafenib-resistant FLT3 mutants sunitinib-resistant FLT3 mutants tandutinib-resistant FLT3 mutants linifanib-resistant FLT3 mutants tamatinib-resistant FLT3 mutants Signaling by FLT3 ITD and TKD mutants Signaling by FLT3 ITD and TKD mutants Negative regulation of FLT3 FLT3 signaling through SRC family kinases FLT3 signaling through SRC family kinases FLT3 signaling by CBL mutants	Pathway 2 Degradation of cysteine and homocysteine FMO oxidises nucleophiles	Drugs 1 Sorafenib Sunitinib XL999 Tandutinib Linifanib Lestaurtinib Midostaurin Ponatinib Nintedanib Pacritinib Tivozanib Fostamatinib Gilteritinib Brigatinib Fedratinib Amuvatinib Quizartinib Pexidartinib Pralsetinib	Drugs 2	Diseases 1 Acute myeloid leukemia (AML)	Diseases 2
Novel	Symbols TRIM31 and BTNL2	Name 1 tripartite motif containing 31	Name2 butyrophilin like 2	Pathway 1 Interferon gamma signaling	Pathway 2 Butyrophilin (BTN) family interactions	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols IFT172 and DNAJC27	Name 1 intraflagellar transport 172	Name2 DnaJ heat shock protein family (Hsp40) member C27	Pathway 1 Hedgehog 'off' state Intraflagellar transport Intraflagellar transport	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols CIT and ABCB9	Name 1 citron rho-interacting serine/threonine kinase	Name2 ATP binding cassette subfamily B member 9	Pathway 1 RHO GTPases activate CIT RHO GTPases activate CIT RHOA GTPase cycle RHOB GTPase cycle RHOC GTPase cycle RAC1 GTPase cycle	Pathway 2 ABC-family proteins mediated transport	Drugs 1 Fostamatinib	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols BDNF and MPPED2	Name 1 brain derived neurotrophic factor	Name2 metallophosphoesterase domain containing 2	Pathway 1 PIP3 activates AKT signaling Constitutive Signaling by Aberrant PI3K in Cancer PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling MECP2 regulates transcription of neuronal ligands BDNF activates NTRK2 (TRKB) signaling Activated NTRK2 signals through RAS Activated NTRK2 signals through PLCG1 Activated NTRK2 signals through PLCG1 Activated NTRK2 signals through PI3K Activated NTRK2 signals through FRS2 and FRS3 Activated NTRK2 signals through FRS2 and FRS3 Activated NTRK2 signals through FYN NTRK2 activates RAC1 NTRK2 activates RAC1 Activated NTRK2 signals through CDK5 NPAS4 regulates expression of target genes	Pathway 2	Drugs 1 CX-717 Copper Chondroitin sulfate Esketamine	Drugs 2	Diseases 1 Congenital central hypoventilation syndrome (CCHS)	Diseases 2
Novel	Symbols RAB10 and EFR3B	Name 1 RAB10, member RAS oncogene family	Name2 EFR3 homolog B	Pathway 1 Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols BBS1 and PEPD	Name 1 Bardet-Biedl syndrome 1	Name2 peptidase D	Pathway 1 BBSome-mediated cargo-targeting to cilium	Pathway 2	Drugs 1	Drugs 2	Diseases 1 Bardet-Biedl syndrome (BBS)	Diseases 2
Novel	Symbols POFUT2 and CLDN14	Name 1 protein O-fucosyltransferase 2	Name2 claudin 14	Pathway 1 O-glycosylation of TSR domain-containing proteins	Pathway 2 Tight junction interactions	Drugs 1	Drugs 2	Diseases 1	Diseases 2 Deafness, autosomal recessive
Novel	Symbols TRIM38 and TSBP1	Name 1 tripartite motif containing 38	Name2 testis expressed basic protein 1	Pathway 1 Interferon gamma signaling	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols AGPS and KCNH7	Name 1 alkylglycerone phosphate synthase	Name2 potassium voltage-gated channel subfamily H member 7	Pathway 1 Plasmalogen biosynthesis Peroxisomal protein import Peroxisomal protein import TYSND1 cleaves peroxisomal proteins	Pathway 2 Voltage gated Potassium channels	Drugs 1	Drugs 2 Enflurane Ibutilide Amitriptyline Doxazosin Promethazine Miconazole Amiodarone Terazosin Vanoxerine Silodosin	Diseases 1 Rhizomelic chondrodysplasia punctata, including: Rhizomelic chondrodysplasia punctata, type I (RCDP1); Rhizomelic chondrodysplasia punctata, type II (RCDP2); Rhizomelic chondrodysplasia punctata, type III (RCDP3)	Diseases 2
Novel	Symbols AFF3 and DPP8	Name 1 ALF transcription elongation factor 3	Name2 dipeptidyl peptidase 8	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols REEP5 and LGR5	Name 1 receptor accessory protein 5	Name2 leucine rich repeat containing G protein-coupled receptor 5	Pathway 1	Pathway 2 Regulation of FZD by ubiquitination	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols TMA16 and FSTL5	Name 1 translation machinery associated 16 homolog	Name2 follistatin like 5	Pathway 1	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols NAT1 and CSMD1	Name 1 N-acetyltransferase 1	Name2 CUB and Sushi multiple domains 1	Pathway 1 Acetylation Paracetamol ADME	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols BZW2 and AGMO	Name 1 basic leucine zipper and W2 domains 2	Name2 alkylglycerol monooxygenase	Pathway 1	Pathway 2 Triglyceride biosynthesis	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols AASS and FSCN3	Name 1 aminoadipate-semialdehyde synthase	Name2 fascin actin-bundling protein 3	Pathway 1 Lysine catabolism	Pathway 2	Drugs 1 Glutamic acid NADH NADPH L-Saccharopine	Drugs 2	Diseases 1 Hyperlysinemia	Diseases 2
Novel	Symbols ZDHHC8 and MICAL3	Name 1 zDHHC palmitoyltransferase 8	Name2 microtubule associated monooxygenase, calponin and LIM domain containing 3	Pathway 1 HDL assembly Maturation of spike protein	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols TYW5 and SATB2-AS1	Name 1 tRNA-yW synthesizing protein 5	Name2 SATB2 antisense RNA 1	Pathway 1 Synthesis of wybutosine at G37 of tRNA(Phe)	Pathway 2	Drugs 1	Drugs 2	Diseases 1	Diseases 2
Novel	Symbols COLEC10 and ALG5	Name 1 collectin subfamily member 10	Name2 ALG5 dolichyl-phosphate beta-glucosyltransferase	Pathway 1 Lectin pathway of complement activation Initial triggering of complement	Pathway 2 Synthesis of dolichyl-phosphate-glucose	Drugs 1	Drugs 2	Diseases 1	Diseases 2

Page 3 out of 58 pages

Search Results : Diabetes