RAB10 and EFR3B

		RAB10	EFR3B
Description		RAB10, member RAS oncogene family	EFR3 homolog B
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Exocyst Cytoplasm Lysosome Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Trans-Golgi Network Cytosol Cytoskeleton Plasma Membrane Adherens Junction Focal Adhesion Cilium Endosome Membrane Membrane Cytoplasmic Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Insulin-responsive Compartment Cell Projection Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Exosome Exocytic Vesicle Endoplasmic Reticulum Tubular Network Secretory Vesicle	Cytoplasm Cytosol Plasma Membrane Actin Cytoskeleton Membrane
	Molecular Function	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Myosin V Binding Cadherin Binding Involved In Cell-cell Adhesion	Protein Binding
	Biological Process	Exocytosis Golgi To Plasma Membrane Transport Axonogenesis Protein Transport Vesicle-mediated Transport Endosomal Transport Antigen Processing And Presentation Polarized Epithelial Cell Differentiation Cellular Response To Insulin Stimulus Golgi To Plasma Membrane Protein Transport Regulated Exocytosis Establishment Of Neuroblast Polarity Endoplasmic Reticulum Tubular Network Organization Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Cell-cell Adhesion Protein Localization To Basolateral Plasma Membrane	Transmission Of Nerve Impulse Social Behavior Phosphatidylinositol Phosphate Biosynthetic Process Protein Localization To Plasma Membrane
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Glycated hemoglobin levels ( 34059833) Immune response to smallpox vaccine (IL-6) ( 22542470) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular hemoglobin concentration ( 32888494) Mean corpuscular volume ( 27863252 32888494) Metabolite levels (HVA) ( 23319000) Metabolite levels (HVA-5-HIAA Factor score) ( 23319000) Metabolite levels (HVA/MHPG ratio) ( 23319000) Platelet distribution width ( 32888494)	A body shape index ( 34021172) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 26426971) Body mass index (age <50) ( 26426971) Body mass index (age>50) ( 26426971) Body mass index in non-asthmatics ( 23517042) Body mass index x sex x age interaction (4df test) ( 26426971) Crohn's disease ( 28067908) Daytime nap ( 33568662) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Inflammatory bowel disease ( 28067908) Type 1 diabetes ( 21980299) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		10 interacting genes: APP CEBPA ENOPH1 EVI5L MICAL1 MTNR1A PPBP RABIF RIMS1 SEPTIN9
Entrez ID		10890	22979
HPRD ID		06692	13824
Ensembl ID		ENSG00000084733	ENSG00000084710
Uniprot IDs		P61026	B3KT90 E7ESK9 Q9Y2G0
PDB IDs		5LPN 5SZJ
Enriched GO Terms of Interacting Partners?			Protein Localization To Basolateral Plasma Membrane Establishment Of Neuroblast Polarity Establishment Of Protein Localization To Endoplasmic Reticulum Membrane Hindgut Development Sperm Cytoplasmic Droplet Intraciliary Transport Particle Insulin-responsive Compartment Cilium Secretory Vesicle Neural Tube Formation Cadherin Binding Involved In Cell-cell Adhesion Endoplasmic Reticulum Tubular Network Organization Exocytic Vesicle Myosin V Binding Exocyst Endoplasmic Reticulum Tubular Network Polarized Epithelial Cell Differentiation Embryonic Epithelial Tube Formation Left/right Axis Specification Negative Regulation Of Keratinocyte Proliferation Intraciliary Transport Particle B Embryonic Eye Morphogenesis Embryonic Camera-type Eye Morphogenesis Spinal Cord Motor Neuron Differentiation Intraciliary Anterograde Transport Sperm Principal Piece Keratinocyte Proliferation Golgi To Plasma Membrane Protein Transport Cell Projection Organization Establishment Of Protein Localization To Endoplasmic Reticulum Epithelial Tube Formation Negative Regulation Of Smoothened Signaling Pathway Cell Differentiation In Spinal Cord Positive Regulation Of Smoothened Signaling Pathway Intracellular Transport Neural Tube Development Cell Projection Ciliary Tip Regulation Of Keratinocyte Proliferation Intraciliary Transport Sperm Midpiece Non-motile Cilium Assembly Digestive Tract Development Limb Development Endoplasmic Reticulum Organization Cellular Localization Anatomical Structure Morphogenesis Establishment Of Protein Localization To Plasma Membrane Establishment Of Localization In Cell Golgi To Plasma Membrane Transport
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?