TMA16 and FSTL5

		TMA16	FSTL5
Description		translation machinery associated 16 homolog	follistatin like 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus	Extracellular Region
	Molecular Function	Protein Binding Preribosome Binding	Calcium Ion Binding Protein Binding Metal Ion Binding
	Biological Process	Ribosome Biogenesis Ribosomal Large Subunit Biogenesis	Cell Differentiation Regulation Of BMP Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Small cell lung carcinoma ( 28604730)	Adult body size ( 32376654) Bipolar disorder ( 31043756) Cerebral amyloid angiopathy x APOEe4 status interaction in Alzheimer’s disease ( 34020725) Chronotype ( 30696823) Colorectal cancer ( 25023989) Coronary artery calcified atherosclerotic plaque score in type 2 diabetes ( 29221444) Diverticular disease ( 30177863) Femur bone mineral density x serum urate levels interaction ( 34046847) Heel bone mineral density x serum urate levels interaction ( 34046847) Height ( 20966902) HOMA-B (corrected for HOMA-IR) ( 30369944) Longevity ( 30294719) Nicotine dependence and major depression (severity of comorbidity) ( 30287806) Retinal detachment or retinal break ( 31816047) Retinitis pigmentosa ( 33514863) Serum immune biomarker levels ( 32066700) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Uterine fibroid number (single vs multiple) ( 30196971)
Interacting Genes		9 interacting genes: AP2M1 APP CASTOR1 CEBPA IKBKG KLHL2 KRTAP10-7 NEDD4L TSPYL2
Entrez ID		55319	56884
HPRD ID		07739	10998
Ensembl ID		ENSG00000198498	ENSG00000168843
Uniprot IDs		Q96EY4	Q8N475
PDB IDs		6LSS 6LU8 8FLA 8FLB 8FLC 8IDT 8IDY 8INE 8INF
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Proteolysis Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Catabolic Process Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Protein Catabolic Process Negative Regulation Of Protein Localization Positive Regulation Of Endocytosis Positive Regulation Of Receptor Internalization Identical Protein Binding Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Protein Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Regulation Of Protein Metabolic Process Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Receptor-mediated Endocytosis Clathrin-coated Pit Regulation Of Protein Catabolic Process Protein Heterodimerization Activity Lipoprotein Particle Regulation Of Receptor Internalization Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Regulation Of Endocytosis CHOP-C/EBP Complex Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Response To Vitamin B2 C/EBP Complex Receptor Internalization Linear Polyubiquitin Binding Negative Regulation Of Sodium Ion Import Across Plasma Membrane Molecular Sensor Activity Cellular Response To L-arginine Endocytosis Notch Signaling Pathway Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway	Double-stranded RNA Binding Single-stranded RNA Binding RNA Helicase Activity Helicase Activity Positive Regulation Of MDA-5 Signaling Pathway MHC Protein Binding Defense Response To Virus Preribosome Binding ATP Hydrolysis Activity Positive Regulation Of RIG-I Signaling Pathway Response To Virus Regulation Of RIG-I Signaling Pathway
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