NR1I3 and MAP4

Number of citations of the paper that reports this interaction (PubMedID 15604093)
0

Data Source:
HPRD (two hybrid)

		NR1I3	MAP4
Description		nuclear receptor subfamily 1 group I member 3	microtubule associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton	Cytoplasm Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Microtubule Associated Complex Plasma Membrane Cilium Axoneme Microtubule Cytoskeleton Axon Ciliary Basal Body Neuron Projection Mitotic Spindle
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Structural Molecule Activity Protein Binding Microtubule Binding Tubulin Binding Microtubule Stabilizing Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Osteoblast Differentiation Regulation Of DNA-templated Transcription Signal Transduction Cell Differentiation Intracellular Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Neuron Projection Development Microtubule Polymerization Microtubule Sliding Establishment Of Spindle Orientation Cell Division Cilium Disassembly Negative Regulation Of Non-motile Cilium Assembly
Pathways
Drugs		Doxylamine Meclizine Ketoconazole Atorvastatin Pheniramine Prasterone 16,17-Androstene-3-Ol Resveratrol Cholesterol Phenolphthalein 3,20-Pregnanedione Hexestrol Triclosan	Paclitaxel Docetaxel Artenimol
Diseases
GWAS			Blood pressure ( 21909110) Body mass index and systole blood pressure (pairwise) ( 33619380) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Diastolic blood pressure ( 27618452 27841878 28739976) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Liver enzyme levels (alkaline phosphatase) ( 33972514) Mean arterial pressure ( 27618448) Medication use (calcium channel blockers) ( 31015401) Pulse pressure ( 27841878) Systolic blood pressure ( 27618452 27841878 28739976 30578418)
Interacting Genes		18 interacting genes: CHD9 DNMT3L FTH1 HNF4A IGH MAP4 MED1 NCOA1 NCOA3 NR0B2 POU1F1 PPARGC1A PSMC4 PSMC5 RXRA SNRPD3 SNX13 SRC	26 interacting genes: CCNB1 CDC42 CDK1 CEBPA CLASP1 ENO2 ERBIN GSK3B IL7R LDLR MARK1 MARK4 NEIL3 NOP58 NR1I3 POT1 RNF10 RXRB RXRG SNTA1 SRPK2 STRBP SUMO2 TERF1 TUBB UBC
Entrez ID		9970	4134
HPRD ID		04858	01141
Ensembl ID		ENSG00000143257	ENSG00000047849
Uniprot IDs		F1DAL4 Q14994	A0A804HKE7 E7EVA0 P27816
PDB IDs		1XV9 1XVP
Enriched GO Terms of Interacting Partners?		Nuclear Receptor Binding Nuclear Receptor-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Peroxisome Proliferator Activated Receptor Signaling Pathway Hormone-mediated Signaling Pathway Nuclear Retinoic Acid Receptor Binding Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Steroid Hormone Receptor Signaling Pathway Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nuclear Thyroid Hormone Receptor Binding Negative Regulation Of RNA Metabolic Process Chromatin Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process MRNA Transcription By RNA Polymerase II Proteasome-activating Activity Regulation Of Thyroid Hormone Receptor Signaling Pathway LBD Domain Binding Nuclear Protein Quality Control By The Ubiquitin-proteasome System Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleus MRNA Transcription Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Peroxisome Proliferator Activated Receptor Binding Regulation Of Vitamin D Receptor Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of RNA Metabolic Process General Transcription Initiation Factor Binding Proteasome Regulatory Particle, Base Subcomplex Progesterone Receptor Signaling Pathway Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Vitamin D Receptor Binding Proteasomal Protein Catabolic Process Rhythmic Process Proteasome Accessory Complex Nuclear Retinoid X Receptor Binding Positive Regulation Of Keratinocyte Differentiation Branching Involved In Mammary Gland Duct Morphogenesis Monocyte Differentiation Nucleoplasm	Positive Regulation Of Macromolecule Metabolic Process Regulation Of Attachment Of Spindle Microtubules To Kinetochore Cyclin B1-CDK1 Complex Positive Regulation Of Organelle Organization Tau-protein Kinase Activity Positive Regulation Of Mitochondrial ATP Synthesis Coupled Electron Transport Organelle Organization Positive Regulation Of Metabolic Process Cytoskeleton Intracellular Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Postsynapse Shelterin Complex Microtubule Cytoskeleton Organization Cell Division Positive Regulation Of Biosynthetic Process Tau Protein Binding Positive Regulation Of Protein Localization To Centrosome Retinoic Acid-responsive Element Binding Mitotic Spindle Mitotic Cell Cycle Phase Transition Cytoskeleton Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nuclear Receptor Activity Nuclear Telomere Cap Complex Telomeric D-loop Disassembly Ventricular Cardiac Muscle Cell Development Cell Cycle Phase Transition Establishment Or Maintenance Of Cell Polarity G-rich Strand Telomeric DNA Binding Regulation Of Cell Cycle Positive Regulation Of Cell Cycle Cilium Disassembly Telomeric Loop Disassembly Nucleoplasm Response To Lipid Microtubule-based Process Regulation Of Protein Localization To Centrosome Telomere Capping Protein Phosphorylation Glutamatergic Synapse Protein Serine Kinase Activity Positive Regulation Of Protein-containing Complex Assembly Protein Tag Activity Phosphorylation G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Organization Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Cell Cycle G1/S Phase Transition
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