NOTCH2NLA and TRPV6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		NOTCH2NLA	TRPV6
Description		notch 2 N-terminal like A	transient receptor potential cation channel subfamily V member 6
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm	Plasma Membrane Membrane Calcium Channel Complex
	Molecular Function	Notch Binding Calcium Ion Binding Protein Binding	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Notch Signaling Pathway Cerebral Cortex Development Cell Differentiation Positive Regulation Of Notch Signaling Pathway	Monoatomic Ion Transport Calcium Ion Transport Regulation Of Calcium Ion-dependent Exocytosis Monoatomic Ion Transmembrane Transport Parathyroid Hormone Secretion Response To Calcium Ion Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane
Pathways		NOTCH2 Activation and Transmission of Signal to the Nucleus NOTCH2 Activation and Transmission of Signal to the Nucleus Expression of NOTCH2NL genes	TRP channels
Drugs
Diseases
GWAS			Alcoholic chronic pancreatitis ( 28754779) Anxiety ( 31906708) Cancer ( 29299148) Mastocytosis ( 32752121)
Interacting Genes		361 interacting genes: ACY3 ADAM12 ADAMTSL3 ADAMTSL4 ADAMTSL5 ADCK5 AGXT ALDH16A1 ALDH3B1 ALPI ALPP ANKS1A AQP1 AQP5 ARID3A ASPSCR1 ATG9A ATP5F1D BCAM BCL6B BLCAP BMP7 BRME1 C11orf87 CA6 CARHSP1 CATSPER1 CCDC26 CCDC93 CCER1 CD164 CDK5R1 CELF5 CERK CHCHD3 CHDH CHIC2 CHRD CHRNG CLDN2 CLEC18A CNNM3 COL8A1 CRACR2A CRCT1 CREB5 CRH CRY2 CSF1 CST2 CST9L CTNNBIP1 CTSG CTSZ CXCL16 CXCL5 CYP21A2 CYSRT1 DAGLB DALRD3 DBH DGCR6 DGKQ DHRS1 DMRT3 DNAL4 DOCK2 DRD5 EFNA3 EIF4E2 ELANE EMC7 EPHB6 ESR2 F10 FAAH FADS2 FAM124B FAM221A FAM74A4 FAM90A1 FARS2 FASLG FBXL18 FBXW5 FOXB1 FRS3 FTHL17 FZD10 GABRD GARIN5B GARIN6 GATA2 GEM GFOD1 GIP GLP1R GLRX3 GLYAT GNAI2 GNE GNMT GSTP1 GTF3C5 H2AC15 HAPLN2 HBA1 HBA2 HBZ HCK HHEX HOXA1 HOXB9 HOXC8 HPCAL1 HSBP1 HSD3B7 HSPA12B HSPBP1 HSPD1 ICAM4 IFI30 IGSF8 IL10 IL2RG INO80B INPP5D INS ITGB2 ITGB4 ITGB5 JOSD1 KCNS2 KCTD15 KIF1A KLHL38 KLK8 KPRP KRT20 KRT83 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP12-4 KRTAP13-2 KRTAP13-3 KRTAP13-4 KRTAP2-3 KRTAP2-4 KRTAP26-1 KRTAP3-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-4 KRTAP4-5 KRTAP4-7 KRTAP5-11 KRTAP5-3 KRTAP5-4 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-3 KRTAP9-4 KRTAP9-8 LCE1A LCE1B LCE1D LCE1E LCE1F LCE2A LCE2B LCE2C LCE2D LCE3A LCE3C LCE3D LCE3E LCE4A LCE5A LIMS2 LIN7A LINC00526 LINC00656 LMNTD2 LMO2 LNX1 LONRF3 LRCH4 LRFN4 LYVE1 MACO1 MAPKBP1 MARK4 MATN3 MELTF MOS MRGBP MRPL40 MTA1 MVP MXD3 MXI1 MYO15B MYPOP NAB2 NAXD NECTIN2 NECTIN3 NEDD9 NEU2 NMU NMUR2 NPBWR2 NPDC1 NPPB NR1D2 NTM NTN4 NUBP2 NUFIP2 OLFM2 OTX1 P2RX4 P2RX7 P2RY6 PCED1A PCED1B PCSK5 PDE9A PGAP6 PGLS PHLDA1 PID1 PIGS PLEKHN1 PLPP2 PLSCR4 POLR2G POM121L8P POMGNT2 PRF1 PRKAA2 PRPF31 PRPS2 PRR19 PRR35 PSMA1 PSMG2 PTGER3 PTK7 PTPMT1 PTPN23 PVR QPRT R3HDM2 RAB3IL1 RAMP3 RASD1 RCHY1 RECK RET RGL2 RNF111 RPS19BP1 RPS28 RTN4RL1 SCNM1 SDCBP SELENOM SEMA3B SEMA4C SHANK3 SHFL SLC22A23 SLC22A5 SLC23A1 SLC25A10 SLC25A6 SLC43A2 SLC5A5 SLC68A1 SLC6A20 SMARCD2 SMARCE1 SMCP SMOC1 SNAI1 SPATA24 SPATA31J1 SPATA8 SPG7 SPINK2 SPPL2C SPRY1 STAC STK16 TAPBPL TBC1D10C TBC1D16 TEDC2 THAP7 THEMIS2 TINAGL1 TLE5 TMEFF2 TMEM150A TMEM231 TMEM41A TMIE TNIP3 TNK2 TNP2 TNS2 TRAPPC14 TRIM27 TRIM42 TROAP TRPV6 TSPAN4 TTPA TXNDC5 UBQLN4 UTP23 UXT VASN WDR25 WT1-AS XCL2 YIPF3 ZDHHC1 ZFTRAF1 ZFYVE21 ZNF124 ZNF319 ZNF32 ZNF330 ZNF408 ZNF414 ZNF417 ZNF439 ZNF440 ZNF446 ZNF497 ZNF580 ZNF581 ZNF587 ZNF648 ZNF672 ZNF688 ZNF786 ZNF837	17 interacting genes: CALB1 CALM1 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-8 MDFI MID2 NEDD4 NOTCH2NLA PDE9A PNMA1 PRKCA PTPN1 S100A10 SNCA TRAF1
Entrez ID		388677	55503
HPRD ID		14833	05982
Ensembl ID		ENSG00000264343	ENSG00000165125
Uniprot IDs		A0A8I5KR58 Q7Z3S9	Q9H1D0
PDB IDs			6BO8 6BO9 6BOA 6D7S 6D7T 6E2F 7K4A 7K4B 7K4C 7K4D 7K4E 7K4F 7S88 7S89 7S8B 7S8C 8FOA 8FOB 8SP8 9CUH 9CUI 9CUJ 9CUK
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratin Filament Protein Binding Keratinization Epidermis Development Hair Cycle Identical Protein Binding Carbon Dioxide Transport Nitric Oxide Transport Purinergic Nucleotide Receptor Signaling Pathway	Keratin Filament Intermediate Filament Regulation Of Synaptic Plasticity Regulation Of Cell Communication Regulation Of Signaling Enzyme Binding Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Exocytosis Regulation Of Cell Junction Assembly Positive Regulation Of Cell Communication Positive Regulation Of Signaling Calyx Of Held Regulation Of Signal Transduction Regulation Of Synapse Organization Calcium Ion Binding Presynaptic Cytosol Postsynaptic Cytosol Transmembrane Transporter Binding Regulation Of Intracellular Signal Transduction Positive Regulation Of Synaptic Transmission Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Metanephric Connecting Tubule Development Terminal Bouton Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Presynaptic Endocytosis Protein-containing Complex Identical Protein Binding Protein Sequestering Activity Receptor Metabolic Process Formation Of Structure Involved In A Symbiotic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Synapse Assembly Regulation Of Exocytosis Response To Fibroblast Growth Factor Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Phosphoprotein Binding Cytosol Modulation Of Chemical Synaptic Transmission Long-term Synaptic Potentiation Postsynapse Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Muscle System Process Regulation Of System Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?