NOTCH2NL and GNMT

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		NOTCH2NL	GNMT
Gene Name		notch 2 N-terminal like	glycine N-methyltransferase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Cytoplasm	Cytoplasm
	Molecular Function	Calcium Ion Binding	Protein Binding Folic Acid Binding Glycine Binding Glycine N-methyltransferase Activity
	Biological Process	Notch Signaling Pathway Multicellular Organismal Development Cell Differentiation	Glycogen Metabolic Process Regulation Of Gluconeogenesis Cellular Protein Modification Process Methionine Metabolic Process One-carbon Metabolic Process Methylation S-adenosylmethionine Metabolic Process Protein Homotetramerization
Pathways
Drugs			S-Adenosylmethionine Glycine S-Adenosyl-L-Homocysteine Citric Acid
Diseases
GWAS
Protein-Protein Interactions		241 interactors: ACY3 ADAMTSL3 ADAMTSL5 ADCK5 AES ALDH3B1 ALPI AQP1 AQP5 ARID3A ASPSCR1 ATG9A BCL6B BLCAP BMP7 C11orf87 C16orf59 C19orf66 C5orf60 CA6 CARHSP1 CARKD CATSPER1 CCDC26 CCDC93 CCER1 CD164 CDK5R1 CERK CHCHD3 CHDH CHIC2 CHRD CHRNG CLDN2 CLEC18A COL8A1 CRACR2A CRCT1 CREB5 CSF1 CST2 CST9L CTSG CTSZ CXCL16 CXCL5 DGCR6 DHRS1 DMRT3 DNAL4 DOCK2 EFNA3 EIF4E2 ELANE EPHB6 ESR2 FAAH FAM124B FAM71C FAM71E2 FAM74A4 FARS2 FASLG FBXL18 FBXW5 FOXB1 FRS3 GABRD GATA2 GEM GFOD1 GIP GLP1R GLRX3 GLYAT GNAI2 GNE GNMT GSTP1 GTF3C5 HBZ HCK HIST1H2AK HOXA1 HPCAL1 HSBP1 HSD3B7 HSPA12B HSPBP1 HSPD1 ICAM4 IFI30 IL2RG INPP5D ITGB2 ITGB5 JOSD1 KCTD15 KIF1A KLHL38 KLK8 KRT20 KRT83 KRTAP10-1 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-4 KRTAP13-3 KRTAP26-1 KRTAP3-1 KRTAP4-11 KRTAP4-12 KRTAP4-2 KRTAP4-7 KRTAP5-6 KRTAP5-9 KRTAP9-2 KRTAP9-4 LCE1B LCE2D LCE3C LCE3E LIMS2 LIN7A LINC00526 LINC00656 LMO2 LNX1 LONRF3 LRCH4 LRFN4 MAPKBP1 MARK4 MATN3 MFI2 MRGBP MRPL40 MTA1 MVP MXD3 MXI1 NAB2 NEU2 NMU NMUR2 NPBWR2 NPDC1 NPPB NR1D2 NUBP2 P2RX4 PCED1A PCED1B PCSK5 PDE9A PGLS PID1 PIGS PLSCR4 POLR2G POM121L8P POMGNT2 PPAP2C PRKAA2 PRPF31 PRPS2 PSMA1 PSMG2 PTGER3 PTPMT1 PTPN23 PVR PVRL2 PVRL3 QPRT R3HDM2 RAB3IL1 RAMP3 RCHY1 RECK RET RGL2 RPS28 RTN4RL1 SCNM1 SDCBP SELM SEMA4C SLC22A23 SLC23A1 SLC25A10 SLC25A6 SLC6A20 SMARCD2 SMARCE1 SMCP SMOC1 SNAI1 SPATA8 SPG7 SPINK2 SPRY1 STK16 TBC1D10C TBC1D16 THAP7 THEMIS2 TINAGL1 TMEM150A TMEM231 TMEM41A TNIP3 TNK2 TNP2 TRIM27 TRIM42 TRPV6 TSPAN4 TXNDC5 UBQLN4 UTP23 UXT WDR25 WT1-AS XCL2 YIPF3 ZFYVE21 ZNF124 ZNF32 ZNF417 ZNF439 ZNF440 ZNF446 ZNF581 ZNF587	18 interactors: ADAMTSL4 ARR3 ARRB1 KRTAP10-3 KRTAP4-2 NIF3L1 NOTCH2NL NUDT18 PLEKHF2 POT1 PRKACA RPSA SDCBP TERF1 TERF2 TERF2IP TINF2 WDYHV1
Entrez ID		388677	27232
HPRD ID		14833	05970
Ensembl ID		ENSG00000213240	ENSG00000124713
Uniprot IDs		Q7Z3S9	Q14749
PDB IDs			1R74 2AZT
Enriched GO Terms of Interacting Partners?		Developmental Process Anatomical Structure Development Negative Regulation Of Cellular Metabolic Process Locomotion Negative Regulation Of Biosynthetic Process Multicellular Organismal Development Response To Lipid Cell Motility Cellular Response To Lipid Movement Of Cell Or Subcellular Component Response To Lipopolysaccharide Positive Regulation Of Immune Response To Tumor Cell RNA Biosynthetic Process Transcription, DNA-templated System Development Response To Molecule Of Bacterial Origin Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Response To External Stimulus Susceptibility To T Cell Mediated Cytotoxicity Formation Of Primary Germ Layer Cellular Response To Stimulus Cellular Process Negative Regulation Of Transcription, DNA-templated Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Regulation Of Protein Metabolic Process Biosynthetic Process Endodermal Cell Differentiation Cell Migration Regulation Of Metabolic Process Regulation Of Cellular Process Response To Stimulus Gene Expression Nitrogen Compound Metabolic Process Organ Development Keratinization Anatomical Structure Morphogenesis Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Cellular Protein Metabolic Process Neutrophil Mediated Immunity Extracellular Matrix Organization Extracellular Structure Organization Susceptibility To Natural Killer Cell Mediated Cytotoxicity Carbon Dioxide Transport Gastrulation Cellular Macromolecule Biosynthetic Process Tissue Development Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin	Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Telomere Maintenance Via Telomere Lengthening Telomere Maintenance Via Telomerase Telomere Maintenance RNA-dependent DNA Replication Telomere Capping Negative Regulation Of Chromosome Organization Regulation Of Chromosome Organization Protein Localization To Chromosome, Telomeric Region Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Negative Regulation Of DNA Replication Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Organelle Organization Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Protein Localization To Chromosome Regulation Of Organelle Organization Telomeric Loop Formation Age-dependent Telomere Shortening Regulation Of DNA Replication Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Telomere Assembly Regulation Of Cellular Component Organization Replicative Cell Aging Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of Telomerase Activity DNA Replication Chromosome Organization Regulation Of Telomerase Activity Organelle Organization Negative Regulation Of DNA Biosynthetic Process Cellular Component Assembly Positive Regulation Of DNA Metabolic Process Protein Localization Homeostatic Process Negative Regulation Of Cellular Metabolic Process Protein Localization To Organelle Regulation Of DNA Biosynthetic Process DNA Metabolic Process Negative Regulation Of Protein ADP-ribosylation DGDP Catabolic Process DADP Catabolic Process Positive Regulation Of Dense Core Granule Biogenesis GDP Catabolic Process Positive Regulation Of DNA Strand Elongation Negative Regulation Of DNA Recombination At Telomere Positive Regulation Of Cellular Metabolic Process
Tagcloud ?		a3 a3s a465tmutation anaplastic astrocytoma atrx challenging diffuse distinguish exome gbm gbms glioblastoma gliomas grade idh1 illuminate landscape lethal multiforme oa2 oa3 oligoastrocytoma sequenced signatures	according classified dehydrogenase dfs differed glycine goal ihc luminal metabolism methyltransferase namely negativity null oxidase pipecolic pipox progesterone sarcosine sardh shorter showing stratified stromal subtype tnbc tumoral univariate varied
Tagcloud (Difference) ?		a3 a3s a465tmutation anaplastic astrocytoma atrx challenging diffuse distinguish exome gbm gbms glioblastoma gliomas grade idh1 illuminate landscape lethal multiforme oa2 oa3 oligoastrocytoma sequenced signatures	according classified dehydrogenase dfs differed glycine goal ihc luminal metabolism methyltransferase namely negativity null oxidase pipecolic pipox progesterone sarcosine sardh shorter showing stratified stromal subtype tnbc tumoral univariate varied
Tagcloud (Intersection) ?