WDR1 and SKIV2L

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		WDR1	SKIV2L
Gene Name		WD repeat domain 1	superkiller viralicidic activity 2-like (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Podosome Extracellular Region Cytoplasm Cytosol Actin Filament Cell Junction Cell Projection Extracellular Vesicular Exosome	Nucleus Nucleoplasm Ski Complex
	Molecular Function	Actin Binding	RNA Binding ATP-dependent RNA Helicase Activity ATP Binding
	Biological Process	Platelet Degranulation Blood Coagulation Sensory Perception Of Sound Platelet Activation Regulation Of Oligodendrocyte Differentiation	Metabolic Process
Pathways		Response to elevated platelet cytosolic Ca2+ Platelet degranulation Platelet activation, signaling and aggregation	Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Cardiovascular disease risk factors ( 21943158) Urate levels ( 18179892) Uric acid levels ( 21294900 22229870)	Age-related macular degeneration ( 23577725 20861866) Prostate cancer ( 23535732)
Protein-Protein Interactions		5 interactors: CARD11 CFL1 CSNK2B GRB2 SKIV2L	11 interactors: CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA SNRPB TNRC17 TSSK2 WDR1 XRN1
Entrez ID		9948	6499
HPRD ID		09199	02724
Ensembl ID		ENSG00000071127	ENSG00000204351
Uniprot IDs		O75083	Q15477
PDB IDs
Enriched GO Terms of Interacting Partners?		Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Axon Guidance Immune Response-regulating Signaling Pathway Morphogenesis Of An Epithelium T Cell Costimulation Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Positive Regulation Of Immune Response Neuron Projection Morphogenesis Tissue Morphogenesis Cell Activation Cell Morphogenesis Involved In Differentiation Innate Immune Response Neuron Projection Development Cell Projection Morphogenesis Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cell Part Morphogenesis Regulation Of Immune Response Positive Regulation Of Immune System Process Neuron Development Platelet Activation Positive Regulation Of Cytoskeleton Organization Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Ras Protein Signal Transduction Cell Morphogenesis Epithelium Development Fc-epsilon Receptor Signaling Pathway Neuron Differentiation Positive Regulation Of Cell-cell Adhesion Cell Projection Organization Phagocytosis Locomotion Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of T Cell Activation Immune Response Regulation Of Immune System Process Positive Regulation Of Activin Receptor Signaling Pathway Positive Regulation Of Cell Activation Defense Response Adiponectin-activated Signaling Pathway	Histone MRNA Metabolic Process Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process RRNA Catabolic Process RRNA Metabolic Process Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process NcRNA Metabolic Process MRNA Catabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay MRNA Metabolic Process RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nucleic Acid Phosphodiester Bond Hydrolysis Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Aromatic Compound Catabolic Process RNA Phosphodiester Bond Hydrolysis Positive Regulation Of Cell Growth RRNA Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Growth Ribosome Biogenesis Cellular Metabolic Process Protein Autophosphorylation DNA Deamination Positive Regulation Of Growth Dosage Compensation By Inactivation Of X Chromosome Cellular Macromolecule Catabolic Process Intracellular MRNA Localization Dosage Compensation
Tagcloud ?		actb actr3 anxa2 anxa6 canine cope dedifferentiation grade histologically hspa9 interesting kit mast mct mcts mutational noteworthy observable oncology paradox pdia3 proliferating proteome reflected tcp1a tcp1e transferrin tryptase tumours
Tagcloud (Difference) ?		actb actr3 anxa2 anxa6 canine cope dedifferentiation grade histologically hspa9 interesting kit mast mct mcts mutational noteworthy observable oncology paradox pdia3 proliferating proteome reflected tcp1a tcp1e transferrin tryptase tumours
Tagcloud (Intersection) ?