SKIV2L and CDK11A

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
BioGRID (two hybrid)

		SKIV2L	CDK11A
Gene Name		superkiller viralicidic activity 2-like (S. cerevisiae)	cyclin-dependent kinase 11A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Ski Complex	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Binding ATP-dependent RNA Helicase Activity ATP Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Cyclin-dependent Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Metabolic Process	Regulation Of Cell Growth Regulation Of Transcription, DNA-templated Protein Phosphorylation Apoptotic Process Mitotic Nuclear Division Regulation Of MRNA Processing Regulation Of Cell Cycle
Pathways		Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis	G2/M Transition Centrosome maturation Mitotic G2-G2/M phases Cell Cycle, Mitotic Recruitment of mitotic centrosome proteins and complexes
Drugs
Diseases
GWAS		Age-related macular degeneration ( 23577725 20861866) Prostate cancer ( 23535732)
Protein-Protein Interactions		11 interactors: CDK11A CDKL5 EXOSC10 EXOSC4 GALNT13 PMPCA SNRPB TNRC17 TSSK2 WDR1 XRN1	6 interactors: B4GALT1 CCNL1 EIF3F GADD45A PIN1 SKIV2L
Entrez ID		6499	728642
HPRD ID		02724
Ensembl ID		ENSG00000204351	ENSG00000008128
Uniprot IDs		Q15477	Q4VBY6 Q5QPR3 Q9UQ88
PDB IDs
Enriched GO Terms of Interacting Partners?		Histone MRNA Metabolic Process Nuclear MRNA Surveillance RNA Surveillance Histone MRNA Catabolic Process RRNA Catabolic Process RRNA Metabolic Process Maturation Of 5.8S RRNA Nuclear-transcribed MRNA Catabolic Process NcRNA Metabolic Process MRNA Catabolic Process Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay MRNA Metabolic Process RNA Catabolic Process Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic RNA Phosphodiester Bond Hydrolysis, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nucleic Acid Phosphodiester Bond Hydrolysis Ribonucleoprotein Complex Biogenesis Regulation Of Cell Growth Nuclear Retention Of Unspliced Pre-mRNA At The Site Of Transcription Aromatic Compound Catabolic Process RNA Phosphodiester Bond Hydrolysis Positive Regulation Of Cell Growth RRNA Processing Nuclear Polyadenylation-dependent RRNA Catabolic Process CUT Catabolic Process Regulation Of Growth Ribosome Biogenesis Cellular Metabolic Process Protein Autophosphorylation DNA Deamination Positive Regulation Of Growth Dosage Compensation By Inactivation Of X Chromosome Cellular Macromolecule Catabolic Process Intracellular MRNA Localization Dosage Compensation	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Regulation Of Cellular Protein Metabolic Process Lactose Biosynthetic Process Regulation Of Protein Metabolic Process Regulation Of Cell Cycle Disaccharide Metabolic Process Regulation Of Protein Phosphorylation Penetration Of Zona Pellucida Positive Regulation Of Epithelial Cell Proliferation Involved In Wound Healing Activation Of MAPKKK Activity Positive Regulation Of Apoptotic Process Involved In Mammary Gland Involution Positive Regulation Of P38MAPK Cascade Regulation Of Acrosome Reaction Regulation Of Phosphorylation Cell Cycle DNA Unwinding Involved In DNA Replication Development Of Secondary Sexual Characteristics Regulation Of P38MAPK Cascade Negative Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Oligosaccharide Biosynthetic Process
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