KIF14 and SVIL

Number of citations of the paper that reports this interaction (PMID 20309963)
11

Data Source:
BioGRID (two hybrid)

		KIF14	SVIL
Gene Name		kinesin family member 14	supervillin
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Kinesin Complex Microtubule Plasma Membrane Membrane Midbody Spindle Midzone	Podosome Nucleus Cytoplasm Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Costamere Invadopodium
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Plus-end-directed Tubulin Binding ATPase Activity Protein Kinase Binding PDZ Domain Binding	Protein Binding Actin Filament Binding
	Biological Process	Regulation Of Cell Growth Microtubule-based Movement Microtubule Depolymerization Mitotic Metaphase Plate Congression Positive Regulation Of Cell Proliferation Regulation Of G2/M Transition Of Mitotic Cell Cycle Cerebellar Granular Layer Structural Organization Cerebellar Purkinje Cell Layer Structural Organization Cerebellar Cortex Development Hippocampus Development Olfactory Bulb Development Cell Proliferation In Forebrain Cerebral Cortex Development Regulation Of Cell Adhesion Regulation Of Cell Migration Cytoskeleton-dependent Intracellular Transport SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Myelination Activation Of Protein Kinase Activity Positive Regulation Of Cytokinesis Regulation Of Rap Protein Signal Transduction Negative Regulation Of Integrin Activation Substrate Adhesion-dependent Cell Spreading Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Neuron Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Establishment Of Protein Localization Response To Docetaxel Trihydrate Mitotic Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle	Cytoskeleton Organization Skeletal Muscle Tissue Development Positive Regulation Of Cytokinesis
Pathways
Drugs
Diseases
GWAS			Normalized brain volume ( 19010793)
Protein-Protein Interactions		1 interactors: SVIL	37 interactors: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF14 KIF22 KIFC3 KMT2A KRT18 LIMA1 LMNA LMNB2 LUC7L2 MIF4GD MKL2 MPHOSPH9 NME2 NR3C1 ODF2 P2RX7 PAN3 PCNXL3 PPARG SH3PXD2A STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		9928	6840
HPRD ID		06605	04992
Ensembl ID		ENSG00000118193	ENSG00000197321
Uniprot IDs		Q15058	O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cytokinesis Regulation Of Cytokinesis Positive Regulation Of Cell Division Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Positive Regulation Of Cell Cycle Process Regulation Of Cell Division Muscle Organ Development Positive Regulation Of Cell Cycle Striated Muscle Tissue Development Muscle Tissue Development Regulation Of Cell Cycle Process Muscle Structure Development	Organelle Organization Regulation Of Cellular Component Organization Mitotic Cell Cycle Process Regulation Of Organelle Organization Mitotic Cell Cycle Cell Cycle Process Cell Cycle Regulation Of Apoptotic Process Regulation Of Cell Death Positive Regulation Of Cellular Biosynthetic Process Intracellular Receptor Signaling Pathway Mitotic Nuclear Division Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Cellular Component Assembly Positive Regulation Of Transcription From RNA Polymerase II Promoter Protein Complex Assembly Positive Regulation Of Transcription, DNA-templated Anatomical Structure Development Nitrogen Compound Metabolic Process Regulation Of Signal Transduction Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Metabolic Process Multicellular Organismal Development Positive Regulation Of Gene Expression Establishment Of Organelle Localization Apoptotic Process Transcription, DNA-templated Programmed Cell Death Regulation Of Signaling Microtubule-based Process Steroid Hormone Mediated Signaling Pathway Developmental Process Cell Death Death Establishment Of Localization In Cell RNA Biosynthetic Process Metaphase Plate Congression Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Positive Regulation Of Organelle Organization Transcription From RNA Polymerase II Promoter Response To Organic Substance G2/M Transition Of Mitotic Cell Cycle Organelle Localization Heterocycle Metabolic Process Establishment Of Protein Localization Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process
Tagcloud ?		affymetrix annotations apdf aurka bicarbonate blpdf bpdf buffered ccnb1 ccne2 cdk1 containingpdf cpdf diamond diluted genechip icodextrin insufficiently ipdf kif11 lpdf mesothelial omentum pdf pmc repressors smc4 u133plus2 uremic	10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Difference) ?		affymetrix annotations apdf aurka bicarbonate blpdf bpdf buffered ccnb1 ccne2 cdk1 containingpdf cpdf diamond diluted genechip icodextrin insufficiently ipdf kif11 lpdf mesothelial omentum pdf pmc repressors smc4 u133plus2 uremic	10p11 a549 abundant actin bipartite bovine bu cdnas comparatively conservation cooh cytoskeleton deleted filaments gland headpiece hela identity message microvilli nh2 originally s3 salivary supervillin sw480 terminus tightly villin
Tagcloud (Intersection) ?