CDC5L and SMARCD1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		CDC5L	SMARCD1
Gene Name		cell division cycle 5-like	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm DNA Replication Factor A Complex Nucleolus Cytoplasm Membrane Nuclear Speck Catalytic Step 2 Spliceosome	SWI/SNF Complex NpBAF Complex NBAF Complex
	Molecular Function	DNA Binding Chromatin Binding Protein Binding Poly(A) RNA Binding WD40-repeat Domain Binding	Transcription Coactivator Activity Protein Binding Protein Complex Scaffold
	Biological Process	MRNA Splicing, Via Spliceosome DNA Repair Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Splicing Gene Expression Signal Transduction Involved In DNA Damage Checkpoint	Nucleosome Disassembly Chromatin Remodeling Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Chromatin-mediated Maintenance Of Transcription
Pathways		Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway	Chromatin modifying enzymes Chromatin organization RMTs methylate histone arginines
Drugs
Diseases
GWAS		Osteoarthritis ( 22763110) Stroke (ischemic) ( 22941190)
Protein-Protein Interactions		69 interactors: AKAP6 AKAP9 BCAS2 CALM1 CCDC136 CDK2 CDKN1A CDKN2A CDT1 CTNNBL1 DISC1 DIXDC1 DST EMID1 ERG EXOC1 EXOC7 GLTSCR1L GOLGA2 GOLGA8EP GOLGA8F GRB14 GSE1 HOOK1 KALRN KANSL1 KDM1A KIF3C KIF5B KRT18 LMO2 MACF1 MCM10 MCM3 MCM4 MCM5 MELK MYT1L ORC1 ORC2 ORC5 PCBD2 PDE4DIP PLRG1 PPFIA2 PPP1CA PPP1R13B PPP1R8 PRPF19 PRPF3 RPA1 RPA2 RPA3 SFR1 SH3BP5 SMARCD1 SPTBN1 SYNE1 TRAF3IP1 TRAK1 TRIO TTF2 WWC1 YWHAG YWHAQ YWHAZ ZNF35 ZNF451 ZSCAN1	44 interactors: ANP32B APOA5 AR C4BPA CALCOCO2 CCDC85B CDC5L CDX2 CORO1A DPF3 EGFL7 ESR1 FEZ1 FOS GATA1 GCC1 HNRNPC HSPB1 IGKC JUN KDM1A KLF1 KRT15 KRT18 LDOC1 MED4 NME1 NONO NR1H4 NR3C1 NUCB2 PAICS PCBD1 PGR PRDX1 PRMT6 RIF1 RPS29 SUV420H1 TNIP2 TP53 USHBP1 VPS37B YWHAG
Entrez ID		988	6602
HPRD ID		04184	03438
Ensembl ID		ENSG00000096401	ENSG00000066117
Uniprot IDs		Q99459	Q96GM5
PDB IDs		2DIM 2DIN
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition G1/S Transition Of Mitotic Cell Cycle Cell Cycle Mitotic Cell Cycle Cell Cycle Process Mitotic Cell Cycle Process DNA Replication DNA-dependent DNA Replication DNA Strand Elongation Involved In DNA Replication DNA Strand Elongation DNA Replication Initiation Organelle Organization Cellular Process DNA Recombinase Assembly Apoptotic Signaling Pathway DNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Potassium Ion Transport Cellular Localization Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Regulation Of Cell Cycle Intracellular Signal Transduction Nitrogen Compound Metabolic Process Positive Regulation Of Cell Death Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Cellular Metabolic Process Establishment Of Localization In Cell Intrinsic Apoptotic Signaling Pathway Nucleotide-excision Repair, DNA Gap Filling Positive Regulation Of Potassium Ion Transmembrane Transport G2/M Transition Of Mitotic Cell Cycle Nucleotide-excision Repair, DNA Damage Removal Regulation Of Intracellular Transport Negative Regulation Of Cell Cycle Positive Regulation Of Apoptotic Process Telomere Maintenance Via Semi-conservative Replication Regulation Of Potassium Ion Transport Cellular Response To Heat Regulation Of Membrane Repolarization Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Regulation Of Cell Cycle Phase Transition RNA Splicing Telomere Maintenance Via Recombination Nuclear DNA Replication Golgi To Plasma Membrane Protein Transport	RNA Biosynthetic Process Gene Expression Transcription, DNA-templated RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Apoptotic Process Positive Regulation Of Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Cell Death Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Chromatin Organization Regulation Of Gene Expression Cellular Response To Organic Substance Response To Organic Substance Developmental Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of RNA Metabolic Process Anatomical Structure Development Transcription From RNA Polymerase II Promoter System Development Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Transcription Initiation From RNA Polymerase II Promoter Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Cell Death Chromosome Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Intracellular Receptor Signaling Pathway Positive Regulation Of Metabolic Process Multicellular Organismal Development DNA-templated Transcription, Initiation Hormone-mediated Signaling Pathway Regulation Of Cell Proliferation Cellular Response To Hormone Stimulus Regulation Of Cellular Process Chromatin Modification
Tagcloud ?		adjuvant adolescents analyse barcodes cdk4 determining digital encoded helicase histopathologic inactivator malignancy mdm2 nanostring neo networks operative osteosarcoma osteosarcomas paediatric panel quantify rb1 recql4 responded runx2 sporadic tp53 unfavourable
Tagcloud (Difference) ?		adjuvant adolescents analyse barcodes cdk4 determining digital encoded helicase histopathologic inactivator malignancy mdm2 nanostring neo networks operative osteosarcoma osteosarcomas paediatric panel quantify rb1 recql4 responded runx2 sporadic tp53 unfavourable
Tagcloud (Intersection) ?